Detalhe da pesquisa
1.
PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFß signaling.
Cell Mol Life Sci
; 81(1): 173, 2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38597967
2.
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.
Nucleic Acids Res
; 50(17): 9948-9965, 2022 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36099415
3.
E2F transcription regulation: an orphan cyclin enters the stage.
EMBO J
; 38(20): e103421, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566762
4.
A catalog of curated breast cancer genes.
Breast Cancer Res Treat
; 191(2): 431-441, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755241
5.
Acute hydroxyurea-induced replication blockade results in replisome components disengagement from nascent DNA without causing fork collapse.
Cell Mol Life Sci
; 77(4): 735-749, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31297568
6.
Topokaryotyping demonstrates single cell variability and stress dependent variations in nuclear envelope associated domains.
Nucleic Acids Res
; 46(22): e135, 2018 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30215776
7.
The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.
Nucleic Acids Res
; 44(7): 3176-89, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26792895
8.
DNA replication and cancer: From dysfunctional replication origin activities to therapeutic opportunities.
Semin Cancer Biol
; 37-38: 16-25, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26805514
9.
Chromatin Dynamics in Genome Stability: Roles in Suppressing Endogenous DNA Damage and Facilitating DNA Repair.
Int J Mol Sci
; 18(7)2017 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698521
10.
Damage-induced DNA replication stalling relies on MAPK-activated protein kinase 2 activity.
Proc Natl Acad Sci U S A
; 110(42): 16856-61, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24082115
11.
Histone H4 lysine 20 methylation: key player in epigenetic regulation of genomic integrity.
Nucleic Acids Res
; 41(5): 2797-806, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23345616
12.
Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication.
Nucleic Acids Res
; 40(2): 477-86, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21937510
13.
A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance.
EMBO Rep
; 12(7): 705-12, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21637299
14.
Temporal phosphoproteomics reveals WEE1-dependent control of 53BP1 pathway.
iScience
; 26(1): 105806, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36632060
15.
Synthetic lethal interaction between WEE1 and PKMYT1 is a target for multiple low-dose treatment of high-grade serous ovarian carcinoma.
NAR Cancer
; 5(3): zcad029, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37325550
16.
ADAM12 expression is upregulated in cancer cells upon radiation and constitutes a prognostic factor in rectal cancer patients following radiotherapy.
Cancer Gene Ther
; 30(10): 1369-1381, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37495855
17.
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
Nat Metab
; 5(4): 642-659, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37012496
18.
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair.
Nat Cell Biol
; 7(2): 195-201, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15665856
19.
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
Cancer Cell
; 3(3): 247-58, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12676583
20.
WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity.
Cell Rep
; 38(3): 110261, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045293