Detalhe da pesquisa
1.
Human leukocytes selectively convert 4S,5S-epoxy-resolvin to resolvin D3, resolvin D4, and a cys-resolvin isomer.
Proc Natl Acad Sci U S A
; 118(51)2021 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911767
2.
Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells.
Proc Natl Acad Sci U S A
; 117(15): 8573-8583, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32220961
3.
Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A4 Hydrolase.
Int J Mol Sci
; 24(8)2023 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108702
4.
Modulation of microRNA processing by 5-lipoxygenase.
FASEB J
; 35(2): e21193, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205517
5.
Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm.
Proc Natl Acad Sci U S A
; 115(8): 1907-1912, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29432192
6.
Capturing LTA4 hydrolase in action: Insights to the chemistry and dynamics of chemotactic LTB4 synthesis.
Proc Natl Acad Sci U S A
; 114(36): 9689-9694, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827365
7.
A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase.
Proc Natl Acad Sci U S A
; 113(4): 972-7, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26755582
8.
GM-CSF- and M-CSF-primed macrophages present similar resolving but distinct inflammatory lipid mediator signatures.
FASEB J
; 31(10): 4370-4381, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637652
9.
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Proc Natl Acad Sci U S A
; 111(31): 11371-6, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25034252
10.
Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor.
Proc Natl Acad Sci U S A
; 111(11): 4227-32, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591641
11.
Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.
J Lipid Res
; 57(9): 1659-69, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27436590
12.
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease.
Biochim Biophys Acta
; 1851(4): 331-9, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152163
13.
Pillars Article: Leukotriene C: A Slow-Reacting Substance from Murine Mastocytoma Cells. Proc. Natl. Acad. Sci. USA. 1979. 76: 4275-4279.
J Immunol
; 200(5): 1538-1542, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463690
14.
Pedro Brugada and Peter Schwartz share the Lefoulon-Delalande Foundation Scientific Prize 2019.
Eur Heart J
; 40(32): 2670, 2019 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31433852
15.
A mutation interfering with 5-lipoxygenase domain interaction leads to increased enzyme activity.
Arch Biochem Biophys
; 545: 179-85, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24480307
16.
Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development.
Proc Natl Acad Sci U S A
; 108(51): 20479-84, 2011 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22143766
17.
Role of basic science in the development of new medicines: examples from the eicosanoid field.
J Biol Chem
; 287(13): 10070-10080, 2012 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22318727
18.
Increased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm.
Proc Natl Acad Sci U S A
; 107(49): 21093-7, 2010 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21078989
19.
Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors.
FASEB J
; 25(4): 1417-27, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228223
20.
Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells.
Proc Natl Acad Sci U S A
; 106(44): 18757-62, 2009 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19846775