Detalhe da pesquisa
1.
Classic Galactosemia: Clinical and Computational Characterization of a Novel GALT Missense Variant (p.A303D) and a Literature Review.
Int J Mol Sci
; 24(24)2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139222
2.
Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Chembiochem
; 22(9): 1597-1608, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400854
3.
Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with APC mutation at the extreme 3'-end.
J Med Genet
; 57(5): 356-360, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591141
4.
The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.
Nucleic Acids Res
; 46(11): 5587-5600, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29733381
5.
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.
J Cell Physiol
; 230(10): 2447-2460, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728514
6.
The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.
J Exp Clin Cancer Res
; 43(1): 151, 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38812026
7.
Histone and DNA Methylation as Epigenetic Regulators of DNA Damage Repair in Gastric Cancer and Emerging Therapeutic Opportunities.
Cancers (Basel)
; 15(20)2023 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894343
8.
Uncoupling p38α nuclear and cytoplasmic functions and identification of two p38α phosphorylation sites on ß-catenin: implications for the Wnt signaling pathway in CRC models.
Cell Biosci
; 13(1): 223, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38041178
9.
The chromatin remodeling factors EP300 and TRRAP are novel SMYD3 interactors involved in the emerging 'nonmutational epigenetic reprogramming' cancer hallmark.
Comput Struct Biotechnol J
; 21: 5240-5248, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37954147
10.
SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage.
Cells
; 12(22)2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37998381
11.
SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer.
Cells
; 12(20)2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37887325
12.
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort.
Cancers (Basel)
; 15(20)2023 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894428
13.
Understanding the Genetic Landscape of Pancreatic Ductal Adenocarcinoma to Support Personalized Medicine: A Systematic Review.
Cancers (Basel)
; 16(1)2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38201484
14.
Identifying novel SMYD3 interactors on the trail of cancer hallmarks.
Comput Struct Biotechnol J
; 20: 1860-1875, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35495117
15.
Identification and Somatic Characterization of the Germline PTEN Promoter Variant rs34149102 in a Family with Gastrointestinal and Breast Tumors.
Genes (Basel)
; 13(4)2022 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35456450
16.
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype.
J Exp Clin Cancer Res
; 41(1): 65, 2022 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35172861
17.
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer.
Cancers (Basel)
; 14(19)2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36230763
18.
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3.
Eur J Med Chem
; 243: 114683, 2022 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36116234
19.
Playing on the Dark Side: SMYD3 Acts as a Cancer Genome Keeper in Gastrointestinal Malignancies.
Cancers (Basel)
; 13(17)2021 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503239
20.
APC Splicing Mutations Leading to In-Frame Exon 12 or Exon 13 Skipping Are Rare Events in FAP Pathogenesis and Define the Clinical Outcome.
Genes (Basel)
; 12(3)2021 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33670833