Associations of Physical Activity and Sedentary Behavior With Survival Time in Older Adults: Path Analysis.

This study investigated the direct and indirect associations of physical activity and sedentary behavior with survival time in older adults. Prospective population-based cohort study used exploratory survey-type methods and physical performance tests in 319 adults aged ≥60 years. Trajectory diagrams were used to represent the initial hypothetical and final models with the relationships of independent, mediating, and dependent variables. Physical activity was indirectly associated with survival time and was mediated by instrumental activities of daily living and functional performance. In contrast, instrumental activities of daily living, functional performance, the number of hospitalizations, and medications mediated the association between duration of sedentary behavior and survival time. The explanatory power of the final model was 19%. Future efforts should focus on increasing the participation and adherence of older adults to exercise programs to improve their physical functions and general health, which may increase their health period and, consequently, their survival time.

Positive Implicit Associations for Physical Activity Predict Physical Activity and Affective Responses During Exercise.

The purpose of this study was to investigate the relationships of implicit associations and explicit evaluations with affective responses during an aerobic exercise session, physical activity, and sedentary behavior in adults. Fifty adults (70% women; median age = 31 years; 25th, 75th percentiles: 24.50, 40.50 years old; body mass index = 25.29 ± 4.97 kg/m2) not engaged in regular physical activity completed an implicit association test and a questionnaire of explicit evaluations and wore an accelerometer for 7 days. After the 7-day period, the participants performed 30 min of moderate-intensity aerobic exercise. Every 5 min, the affective response and the perception of effort were recorded. Participants who had more positive implicit associations toward physical activity (vs. sedentary behavior) reported higher affective responses during exercise and engaged in more moderate to vigorous physical activity. Encouraging pleasant physical activity may act to partially improve future physical activity through automatic motivational processes.

Effects of aerobic exercise combined with resistance training on health-related physical fitness in adolescents: A randomized controlled trial.

Background: /Objective: This study aimed to compare the effects of two combined training methods on health-related physical fitness components in adolescents. Methods: Seventy-six adolescents (16.1 ± 1.1 years, n = 44 female) were randomized into groups of moderate-intensity continuous training combined with resistance training (MICT + RT), high-intensity interval training combined with resistance training (HIIT + RT), or Control. The training sessions were performed twice weekly for 12 weeks. The health-related physical fitness components evaluated were: body composition, muscular and cardiorespiratory fitness. Results: The intervention groups had a significant reduction in body fat percentage and improvement in abdominal repetitions and VO2peak after 12 weeks of combined exercise program (p < 0.001). Intervention effects were found to significantly reduce body fat percentage for the MICT + RT and HIIT + RT groups compared to the control group (mean difference: -3.8; 95% CI: -6.2; -1 0.3; mean difference: -4.7; 95%CI: -7.1; -2.3, respectively). For muscle fitness, significant effects of the intervention were found in increasing the number of abdominal repetitions favoring the MICT + RT group compared to the control group (mean difference: 9.5; 95% CI: 4.4; 14.7) and HIIT + RT compared to the control group (mean difference: 14.1; 95% CI 9; 19.3). For cardiorespiratory fitness, significant effects of the intervention on improving VO2peak were found in the experimental groups (MICT + RT vs Control group: mean difference: 4.4; 95% CI: 2.2; 6.6; and HIIT + RT vs. Control group: mean difference: 5.5, 95% CI: 3.3; 7.7). Conclusion: The results suggest that 12 weeks of training using MCIT + RT or HIIT + RT showed a similar effect for health-related physical fitness components in adolescents.

Exercise training ameliorates adrenergic control in spontaneously hypertensive rats.

The goal of this study was to examine vascular control after sympathetic stimulation by tyramine infusion in hypertensive rats submitted to swimming training. To this end, male rats were assigned to the following groups: sedentary (SN) and trained normotensive (TN), sedentary (SH) and trained hypertensive (TH). Arterial pressure (AP), heart rate (HR), HR variability (HRV), AP variability (APV), and cardiac autonomic function were recorded. Following, infusion of tyramine was administrated. The TN and TH showed a lower resting HR compared with their respective sedentary groups (p < .05). Pressure levels were less in TH than SH (p < .05). The TH showed a higher HRV together with a lower APV in comparison to SH (p < .05). The sympathetic modulation of HRV and APV was lower in TH than in SH (p < .05). Both trained groups presented an increased parasympathetic modulation of HRV compared with their respective sedentary groups (p < .05). The TN and TH groups had a higher vagal effect in comparison with their respective sedentary groups (p < .001). The sympathetic effect was lower in TH than in SH (p < .001). Pressor and HR responses to tyramine in different doses were attenuated in TH (p < .001). Further analysis showed a significant association between infusion of tyramine and normalized LF component of HRV (r = 0.84, p < .001), systolic APV (r = 0.58, p < .001) and diastolic APV (r = 0.49, p < .001). In conclusion, exercise training provokes less pressor response variation by tyramine infusion in hypertensive animals suggesting sympathetic nerve endings adjustments and decrease of the vasoconstrictor effect attenuates injury caused by hypertension improving cardiovascular autonomic dysfunction, which can be associated with sympathetic attenuation.

Association between frailty and the combination of physical activity level and sedentary behavior in older adults.

BACKGROUND: The combined association of physical activity and sedentary behavior with adverse health factors is not yet clear in the literature. A combined analysis of physical activity level and sedentary behavior may provide evidence of the interrelation between these behavioral variables and the frailty syndrome. Thus, the aim of this study was to examine the relationship between physical activity level, sedentary behavior and frailty in older adults. METHODS: In this study, we evaluated 457 older adults (age range = 60 to 96 years old) from the Longitudinal Study of the Elderly Health of Alcobaça, Bahia. The frailty condition was defined by the presence of three or more of the following criteria: unintentional weight loss, slow walking speed measured over a 4.57 m test, a reduction of manual grip strength and exhaustion. Based upon these criteria, participants were classified as non-frail or frail. Physical activity level and time spent in sedentary behavior were assessed with the International Questionnaire of Physical Activity. Descriptive statistics were used to characterize the sample. To examine the combined association of physical activity and sedentary behavior with frailty, chi-square and Poisson regression tests were used. Statistical significance was defined as p ≤ 0.05. RESULTS: The prevalence of frailty was 8.8% (n = 40), with higher prevalence observed with increasing age. Low physical activity level combined with excessive time spent in sedentary behavior (physical activity level < 150 min/wk. and sedentary behavior ≥540 min/day) was associated with frailty, resulting in a prevalence ratio of 2.83 (95% CI, 1.23 to 6.52). CONCLUSION: Frailty is more prevalent among older adults who exhibit insufficient levels of physical activity combined with a great amount of time spent in sedentary behavior, even when adjusted for sociodemographic factors.

Validity of the Marshall Sitting Questionnaire in people with multiple sclerosis.

This study examines the validity of the Marshall Sitting Questionnaire (MSQ) in people with multiple sclerosis (MS) and presents a prediction model to improve the accuracy of the MSQ estimates. Participants (n = 63 [15M and 48F], age: 56.6 ± 7.3 years) wore an accelerometer on the hip for a 7-day period and completed the MSQ. Sedentary behaviour (SB) estimates were computed as min/day for both the MSQ and accelerometer. Associations between the two methods were examined using the Pearson correlation and agreement was assessed using a Bland-Altman plot. A linear prediction model was developed to improve the accuracy of the MSQ estimates using a selection of predictor variables routinely collected in MS research. There was a moderate correlation between MSQ and accelerometer SB estimates (r = 0.34, p < 0.01). The Bland-Altman plot indicated that the MSQ overestimated SB (mean bias: 80.54 min/day, 95% limits of agreement: -410.5 to 571.5 min/day). The prediction model improved the MSQ estimates by 39% and virtually eliminated measurement bias (mean bias:-0.21 min/day; 95% limits of agreement:-109.8 to 109.4 min/day). The results indicate preliminary evidence for the validity of the MSQ in people with MS, and support the application of an alternative prediction model to improve the accuracy of the MSQ estimates. Abbreviations: SB = sedentary behaviour; MS = multiple sclerosis; MSQ = Marshall Sitting Questionnaire; PA = physical activity; EDSS = Expanded Disability Status Scale; LPA = light physical activity; MVPA = moderate-to-vigorous physical activity; GLTEQ = Godin Leisure Time Exercise Questionnaire; PDDS = Patient-Determined Disease Steps; RMSE = root mean square error.

A Systematic Review With Meta-Analysis of Mindful Exercises on Rehabilitative Outcomes Among Poststroke Patients.

OBJECTIVE: To critically evaluate the rehabilitative effects of mindful exercises for poststroke patients. DATA SOURCES: Six databases (PubMed, Physiotherapy Evidence Database, Cochrane Library, Web of Science, Wanfang, Chinese National Knowledge Infrastructure) and reference lists of relevant articles were searched. STUDY SELECTION: Randomized controlled trials on the effects of mindful exercises on rehabilitative outcomes such as sensorimotor function, gait speed, leg strength, aerobic endurance, cognitive function, and overall motor function. DATA EXTRACTION: Two investigators independently screened eligible studies according to the eligible criteria, extracted data, and assessed risk of bias. DATA SYNTHESIS: A total of 20 studies that satisfied the eligibility criteria were finally included. The sum scores of 5-9 points in the adapted Physiotherapy Evidence Database scale indicates low-to-medium risk of bias. The study results of meta-analysis indicate that mindful exercise intervention was significantly associated with improved sensorimotor function on both lower limb (standardized mean difference=0.79; 95% confidence interval, 0.43-1.15; P<.001; I2=62.67%) and upper limb (standardized mean difference=0.7; 95% confidence interval, 0.39-1.01; P<.001; I2=32.36%). CONCLUSIONS: This review suggests that mindful exercises are effective in improving sensorimotor function of lower and upper limbs in poststroke patients. The effects on gait speed, leg strength, aerobic endurance, overall motor function, and other outcomes (eg, cognitive function, gait parameters) require further investigation for allowing evidence-based conclusions.

Number of days required for reliably estimating physical activity and sedentary behaviour from accelerometer data in older adults.

The purpose of the study was to examine the minimum number of monitoring days for reliably estimating physical activity (PA) and sedentary behaviour (SB) from accelerometer data in older adults. Forty-two older adults from a local senior centre participated in this study. Participants wore an ActiGraph wGT3X-BT on the right hip for 7 consecutive days. Accelerometer data were downloaded to a computer and converted to activity count data in 60s epochs. Time spent in SB and different PA intensity categories were estimated with commonly used activity count cut-points. Participants with at least 7 valid days of monitoring (≥10 h.day-1) were included in the analysis. Intraclass correlation coefficients (ICC) were calculated for determining single-day monitoring reliability. The Spearman-Brown prophecy formula was used to estimate the minimum number of monitoring days required for achieving an ICC of 0.80. Single-day ICC values for time spent in SB and PA intensity categories ranged from 0.45 to 0.61. Minimum number of monitoring days required for achieving an ICC of 0.80 ranged from 2.5 to 4.9 days. In this study, a minimum of 5 consecutive days of monitoring was required for reliably estimating SB and PA from accelerometer data in older adults.

A Cross-Sectional Study of the Relationship of Physical Activity with Depression and Cognitive Deficit in Older Adults.

The aim of this study was to examine the association of physical activity with depression and cognition deficit, separately and combined, in Brazilian older adults. We analyzed data from 622 older adults. Physical activity was assessed using the International Physical Activity Questionnaire. Depressive symptoms were assessed using the Geriatric Depression Scale, while cognitive deficit was assessed using the Mini-Mental State Examination. Multinomial logistic regressions were used to assess associations of depression and cognitive deficit with sociodemographic, health, and behavioral variables. Prevalence of physical inactivity (< 150 min of moderate-to-vigorous physical activity/ week), depression, and cognitive deficit were 35.7%, 37.4%, and 16.7%. Physical inactivity was associated with depression (OR: 1.83, 95% CI: 1.14-2.94) and with depression and cognitive deficit combined (OR: 4.23, 95% CI: 2.01-8.91). Physically inactive participants were also more likely to present limitations in orientation and language functions. Physical inactivity was associated with depression and also with depression and cognitive deficit combined in older adults.

Socio-demographic, clinical and health behavior correlates of sitting time in older adults.

BACKGROUND: Identifying correlates of sedentary behavior in older adults is of major importance to healthcare. To our knowledge, there are no population studies in Latin America examining which factors are associated to high sitting time in older adults. Thus, the purpose of this study is to identify socio-demographic, clinical, and health behavior correlates of sitting time in a representative sample of older adults living in Southeastern Brazil. METHODS: A cross-sectional study was conducted in twenty-four municipalities of the Triangulo Mineiro region in the State of Minas Gerais, Southeastern Brazil. A structured questionnaire was applied to obtain information on socio-demographic, clinical, and health behavior factors. Overall sitting time was assessed using a self-report instrument. A Multiple Correspondence Analysis was used to verify the association of sitting time with socio-demographic, clinical, and health behavior factors. RESULTS: 3,296 older adults (61.5% women and 38.5% men) were included in the analysis. The overall median was 240.0 minutes of sitting time/day. The Multiple Correspondence Analysis showed that the group with the highest sitting time presented the following characteristics: women, age greater than 70 years, unschooled status, arterial hypertension, diabetes mellitus, use of medication, poor self-rated health, dependence in basic activities of daily living, and absence of regular physical activity. CONCLUSION: This study reveals that socio-demographic, clinical, and health behavior factors are associated with high sitting time in older adults from Southeastern Brazil. The results may help to identify older adults that should be targeted in interventions aiming at reducing sitting time.

The use of wearable resistance and weighted vest for sprint performance and kinematics: a systematic review and meta-analysis.

Wearable resistance (WR) and weighted vests (WV) can be used in almost all training conditions to enhance sprint performance; however, positioning and additional mass are different in WV and WR strategies, affecting performance and kinematics differently. We aimed to systematically review the literature, searching for intervention studies that reported the acute or chronic kinematic and performance impact of WV and WR and comparing them. We analyzed Pubmed, Embase, Scopus, and SPORTDiscuss databases for longitudinal and cross-over studies investigating sprint performance or kinematics using an inverse-variance with a random-effect method for meta-analysis. After the eligibility assessment, 25 studies were included in the meta-analysis. Cross-over WR and WV studies found significantly higher sprint times and higher ground contact times (CT) compared to unloaded (UL) conditions. However, WR presented a lower step frequency (SF) compared to UL, whereas WV presented a lower step length (SL). Only one study investigated the chronic adaptations for WR, indicating a superiority of the WR group on sprint time compared to the control group. However, no difference was found chronically for WV regarding sprint time, CT, and flight time (FT). Our findings suggest that using WV and WR in field sports demonstrates overload sprint gesture through kinematic changes, however, WR can be more suitable for SF-reliant athletes and WV for SL-reliant athletes. Although promising for chronic performance improvement, coaches and athletes should carefully consider WV and WR use since there is no supporting evidence that WV or WR will impact sprint performance, CT, and FT.

The Influence of L-menthol on Time Trial Running Performance in Recreational Runners.

Purpose: This study investigated the effects of combined mouth rinse and topical application of L-menthol on perceptual responses and running performance under thermoneutral conditions (22 ± 2°C and 30-60% relative humidity). Methods: Twelve recreational male runners (age: 31.7 ± 3.8 years; age range: 27-39 years) completed a familiarization, a control test (CON) and two maximal 10-km time trials (counterbalanced randomized crossover design) performed in different days with a non-thermal cooling intervention (combined application of a L-menthol mouth rinse and topical L-menthol gel - MEN) or placebo (PLA). Performance and perceptual measures (thermal sensation, thermal comfort, ratings of perceived exertion and affective response) were recorded for every km completed in the 10-km test. Results: Performance time was lower in MEN (P = 0.03) and PLA (P = 0.003) compared to CON, but no differences were found between MEN vs PLA (P = 1.00). All perceptual responses increased over time in all conditions (P < 0.0001), but only the thermal sensation was lower (P = 0.01) in the MEN compared to CON. Conclusion: L-menthol strategies promote fresh sensations and may improve running performance in 10-km time trial in recreational runners, but the performance improvement could mainly be due to a placebo effect.

Effects of a Physical Exercise Program and Health Advice on Sedentary Behavior of Adolescents.

Sedentary behavior (SB) is a risk factor for chronic non-communicable diseases. This study aimed to assess the effects of an extracurricular physical exercise program and health advice on SB in adolescents. This was a non-randomized experimental study involving 19 adolescents divided into an intervention group (IG) and a control group (CG), aged 13-16 years from a public school in a Brazilian municipality. SB was measured using self-reports and accelerometers. The intervention included physical exercise and health advice. Repeated measures analysis of variance with a significance level of α = 5% was used. There was a time*group interaction for the subscapular fold ((pre IG = 16.30 mm vs. CG = 13.44 mm, post IG = 14.00 mm vs. CG = 15.89 mm) p = 0.001), and VO2MAX ((pre IG = 32.75 mL/kg/min vs. CG = 30.66 mL/kg/min, post IG = 35.76 mL/kg/min vs. CG = 29.28 mL/kg/min) p = 0.008). The accelerometer showed significant differences between groups in the total SB ((pre IG = 647.49 min/day vs. CG = 535.24 min/day, post IG = 614.02 min/day vs. CG = 586.97 min/day) p = 0.045), with a significant decrease in the IG. In conclusion, an extracurricular physical exercise program and health advice was effective in reducing SB in adolescents.

Time Reallocations From Sedentary Behavior to Physical Activity and Cardiovascular Risk Factors in Children and Adolescents: A Systematic Review.

BACKGROUND: Recent statistical approaches have allowed consideration of the integrated relationships between sedentary behavior (SB) and physical activity (PA) with different health outcomes. The present paper aimed to systematically review the literature and synthesize evidence about associations between hypothetical reallocations from SB to different PA intensities and cardiovascular risk factors in youth. METHODS: A systematic search of 8 databases was performed. Observational studies with a population of children and/or adolescents and based on statistical analysis that investigated the associations between time reallocations from SB to PA and cardiovascular risk factors were included. RESULTS: Twenty-eight studies met the inclusion criteria. Level of evidence (derived from cross-sectional studies) indicated that the reallocation from SB to moderate to vigorous PA was beneficially associated with adiposity, cardiorespiratory fitness, and cardiometabolic biomarkers in youth. Reallocation from SB to light PA was not associated with the analyzed outcomes. Associations derived from longitudinal studies were mostly inconclusive. CONCLUSION: Cardiovascular risk factors could be improved by increasing moderate to vigorous PA at the expense of time spent in SB in pediatric populations. Prospective studies or studies investigating the effects of reallocating sedentary bouts to PA are needed.

Ischemic Preconditioning Improves the Bench-Press Maximal Strength in Resistance-Trained Men.

We investigated whether acute ischemic preconditioning (IPC) would affect upper limb maximal strength performance in resistance-trained men. Using a counterbalanced randomized crossover design, fifteen men (29.9 ± 5.9 yrs.; 86.3 ± 9.6 kg; 8.0 ± 5.0 yrs. resistance training experience) performed one-repetition maximum (1-RM) bench press tests on three different occasions: control, 10 min post-IPC or 10 min post-placebo (SHAM). One-way analysis of variance showed that the post-IPC condition increased (P < 0.0001) 1-RM loads compared to both control and post-SHAM (control 113.3 ± 15.9 kg vs. SHAM 113.9 ± 15.8 kg vs. IPC 115.7 ± 15.6 kg), while control and SHAM did not differ (P > 0.05). Individual results showed that 13 participants (~87%) improved their performance post-IPC compared to control, and 11 participants (~73%) performed better post-IPC compared to post-SHAM. Reported session rating of perceived exertion (RPE) was lower (P < 0.0001) post-IPC (8.5 ± 0.6 arb.u) compared to control (9.3 ± 0.5 arb.u) and post-SHAM (9.3 ± 0.5 arb.u). Therefore, we conclude that IPC acutely improves upper limb maximal strength performance and reduces session-RPE in resistance-trained men. These results suggest an acute ergogenic effect of IPC for strength and power sports such as powerlifting.

Current Perspectives of Cross-Country Mountain Biking: Physiological and Mechanical Aspects, Evolution of Bikes, Accidents and Injuries.

Mountain biking (MTB) is a cycling modality performed on a variety of unpaved terrain. Although the cross-country Olympic race is the most popular cross-country (XC) format, other XC events have gained increased attention. XC-MTB has repeatedly modified its rules and race format. Moreover, bikes have been modified throughout the years in order to improve riding performance. Therefore, the aim of this review was to present the most relevant studies and discuss the main results on the XC-MTB. Limited evidence on the topic suggests that the XC-MTB events present a variation in exercise intensity, demanding cardiovascular fitness and high power output. Nonetheless, these responses and demands seem to change according to each event. The characteristics of the cyclists differ according to the performance level, suggesting that these parameters may be important to achieve superior performance in XC-MTB. Moreover, factors such as pacing and ability to perform technical sections of the circuit might influence general performance. Bicycles equipped with front and rear suspension (i.e., full suspension) and 29″ wheels have been shown to be effective on the XC circuit. Lastly, strategies such as protective equipment, bike fit, resistance training and accident prevention measures can reduce the severity and the number of injuries.

Pedometers and Accelerometers in Multiple Sclerosis: Current and New Applications.

Pedometers and accelerometers have become commonplace for the assessment of physical behaviors (e.g., physical activity and sedentary behavior) in multiple sclerosis (MS) research. Current common applications include the measurement of steps taken and the classification of physical activity intensity, as well as sedentary behavior, using cut-points methods. The existing knowledge and applications, coupled with technological advances, have spawned new opportunities for using those motion sensors in persons with MS, and these include the utilization of the data as biomarkers of disease severity and progression, perhaps in clinical practice. Herein, we discuss the current state of knowledge on the validity and applications of pedometers and accelerometers in MS, as well as new opportunities and strategies for the improved assessment of physical behaviors and disease progression, and consequently, personalized care.

Time-use movement behaviors are associated with scores of depression/anxiety among adolescents: A compositional data analysis.

Movement behaviors have been associated with mental health. The purposes of this study were to examine the association between movement behaviors and scores of depression/anxiety among adolescents and to determine the difference in depression/anxiety associated with reallocating time between different movement behaviors. This cross-sectional study included 217 Brazilian adolescents (15 to 18 years old, 49.3% female). Adolescents wore an accelerometer for one week to assess the four-movement behaviors which include sleep, sedentary behavior (SB), light physical activity (LPA), and moderate-to-vigorous physical activity (MVPA). The depression/anxiety score was calculated by factor analysis using the 12-item General Health Questionnaire. Compositional data analyses were used to examine the association between movement behavior and the depression/anxiety score. Compositional isotemporal substitution models estimated the change in depression/anxiety score associated with reallocating 10, 30, and 60 min between movement behaviors. The composition of movement behaviors was significantly associated with depression/anxiety scores (p < 0.05). Replacing time from SB to LPA was associated with improvement in the depression/anxiety score, while the inverse was associated with an increase in this score. Replacing time of LPA with MVPA was associated with worsening in the depression/anxiety score. The 24-h time distribution of the day may play a crucial role in mental health. Compositions with more time spent in LPA at the expense of less SB are associated with improvement in the scores of depression/anxiety. The type of MVPA may moderate its effects on depression/anxiety in adolescents. Holistic interventions including the full range of movement behaviors may be a gateway to reduce the levels of depression/anxiety in adolescence.

Physical activity, sedentary behavior and functionality in older adults: A cross-sectional path analysis.

Disability is negatively associated with the health of older adults, and it can be mediated by healthy lifestyles and behaviors throughout one's life. In this context, understanding the interrelationships between sedentary behavior, physical activity and functionality may assist in the implementation of effective public health actions. Thus, the aim of the present study was to investigate the relationships between both physical activity and sedentary behavior and functionality in older adults and the possible mediators. The variables analyzed were selected according to the content analysis of International Classification of Functioning, Disability and Health model, and included activity, participation, health conditions, body functions and structures, environmental factors and personal factors. 419 individuals participated in the study. Physical activity was directly associated with disability in instrumental activities of daily living (IADL), and the association was mediated by self-esteem, aerobic endurance, and agility/balance. Sedentary behavior was indirectly associated with IADL disability, and the association was mediated by aerobic resistance, nutritional status, and agility/balance. Regarding the basic activities of daily living (BADL), physical activity showed an indirect association mediated by aerobic resistance and IADL. The association of sedentary behavior with BADL was mediated by aerobic resistance and lower limb flexibility. These results reinforce the idea that functionality is multidimensional, and the mediating factors must be considered when strategies for promoting physical activity and reducing sedentary behavior are designed.

Physical Activity, Sport Practice and Cardiovascular Risk Factors in Workers From a Public Hospital: A Trajectory Analysis.

Background: Studies have demonstrated the positive effects of physical activity on cardiovascular risk factors. Longitudinal studies using modeled trajectories are necessary to understand patterns of physical activity and association with cardiovascular risk factors. Objective: To analyze the association between sports practice in young people and current physical activity with the trajectory of cardiovascular risk factors in workers at a public hospital. Methods: Four hundred and seventeen workers was followed for four years reporting Physical Activity, health status, lifestyle behaviors and socio-demographic characteristics. Group-based trajectory modeling identified the trajectories of PA and associations with time-stable and time-varying covariates. We considered a range of sociodemographic and health and lifestyle factors as potential covariates. Results: The results shows the association between participation in sports activities in youth and current physical activity and trajectories of cardiovascular risk, adjusted for sex and age (p < 0.05). Adults who reported having played sports in their youth and are currently active have a lower risk of having a history of obesity and low HDL-c than workers who did not play sports in their youth and are currently sedentary 0.690 (0.565-0.844) obesity, 0.647 (0.500-0.837) low HDL-c. Conclusion: The practice of sports in youth and current physical activity is a protective factor against the trajectory of obesity and low HDL-c, mainly in female workers. Programs to encourage the practice of physical activity should be carried out in order to reduce cardiovascular risk factors and prevent chronic diseases in workers.