Detalhe da pesquisa
1.
Once-daily oral small-molecule glucagon-like peptide-1 receptor agonist lotiglipron (PF-07081532) for type 2 diabetes and obesity: Two randomized, placebo-controlled, multiple-ascending-dose Phase 1 studies.
Diabetes Obes Metab
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751362
2.
A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of danuglipron (PF-06882961), an oral small-molecule glucagon-like peptide-1 receptor agonist, in Japanese adults with type 2 diabetes mellitus.
Diabetes Obes Metab
; 25(3): 805-814, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36433713
3.
A phase 2a, randomized, double-blind, placebo-controlled, three-arm, parallel-group study to assess the efficacy, safety, tolerability and pharmacodynamics of PF-06835919 in patients with non-alcoholic fatty liver disease and type 2 diabetes.
Diabetes Obes Metab
; 25(4): 992-1001, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36515213
4.
Tolerability, safety and pharmacodynamics of oral, small-molecule glucagon-like peptide-1 receptor agonist danuglipron for type 2 diabetes: A 12-week, randomized, placebo-controlled, Phase 2 study comparing different dose-escalation schemes.
Diabetes Obes Metab
; 25(10): 2805-2814, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37311722
5.
The association between phthalates and metabolic syndrome: the National Health and Nutrition Examination Survey 2001-2010.
Environ Health
; 15: 52, 2016 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27079661
6.
Gender and racial/ethnic differences in the associations of urinary phthalate metabolites with markers of diabetes risk: National Health and Nutrition Examination Survey 2001-2008.
Environ Health
; 13(1): 6, 2014 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24499162
7.
Effect of Renal Impairment on the Pharmacokinetics of a Single Oral Dose of Danuglipron in Participants With Type 2 Diabetes.
J Clin Pharmacol
; 64(4): 449-460, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37840155
8.
Phase 2 study of the efficacy and safety of ponsegromab in patients with cancer cachexia: PROACC-1 study design.
J Cachexia Sarcopenia Muscle
; 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38500292
9.
First trimester PAPP-A levels correlate with sFlt-1 levels longitudinally in pregnant women with and without preeclampsia.
BMC Pregnancy Childbirth
; 13: 85, 2013 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23557166
10.
Inhibition of Diacylglycerol Acyltransferase 2 Versus Diacylglycerol Acyltransferase 1: Potential Therapeutic Implications of Pharmacology.
Clin Ther
; 45(1): 55-70, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36690550
11.
Efficacy and Safety of Oral Small Molecule Glucagon-Like Peptide 1 Receptor Agonist Danuglipron for Glycemic Control Among Patients With Type 2 Diabetes: A Randomized Clinical Trial.
JAMA Netw Open
; 6(5): e2314493, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37213102
12.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
J Med Chem
; 65(12): 8208-8226, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647711
13.
Energy intake as a short-term biomarker for weight loss in adults with obesity receiving liraglutide: A randomized trial.
Obes Sci Pract
; 7(3): 281-290, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34123395
14.
Danuglipron (PF-06882961) in type 2 diabetes: a randomized, placebo-controlled, multiple ascending-dose phase 1 trial.
Nat Med
; 27(6): 1079-1087, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34127852
15.
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Liver-Targeting Acetyl-CoA Carboxylase Inhibitor (PF-05221304): A Three-Part Randomized Phase 1 Study.
Clin Pharmacol Drug Dev
; 9(4): 514-526, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065514
16.
Labor therapeutics and BMI as risk factors for postpartum preeclampsia: A case-control study.
Pregnancy Hypertens
; 10: 177-181, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29153674
17.
The Association of Estrogen Receptor-ß Gene Variation With Salt-Sensitive Blood Pressure.
J Clin Endocrinol Metab
; 102(11): 4124-4135, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28938457
18.
Luteinizing hormone correlates with adrenal function in postmenopausal women.
Menopause
; 19(11): 1280-3, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22713862
19.
Increased sensitivity to angiotensin II is present postpartum in women with a history of hypertensive pregnancy.
Hypertension
; 55(5): 1239-45, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20308605
20.
Smoking cessation and associated risk of metabolic syndrome in women.
Womens Health (Lond)
; 8(4): 367-9, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22757728