Detalhe da pesquisa
1.
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.
Cell
; 170(1): 199-212.e20, 2017 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666119
2.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863010
3.
Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Mol Cell
; 71(4): 554-566.e7, 2018 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30078722
4.
SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells.
Nucleic Acids Res
; 52(5): e26, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281241
5.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Nature
; 568(7753): 551-556, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30971823
6.
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Nature
; 561(7721): 132-136, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30150775
7.
Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability.
Nature
; 563(7733): E32, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279576
8.
Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 561(7723): 420, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046103
9.
CBL mutations drive PI3K/AKT signaling via increased interaction with LYN and PIK3R1.
Blood
; 137(16): 2209-2220, 2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512474
10.
Discovery of a Potent Deubiquitinase (DUB) Small-Molecule Activity-Based Probe Enables Broad Spectrum DUB Activity Profiling in Living Cells.
Angew Chem Int Ed Engl
; 62(47): e202311190, 2023 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37779326
11.
Interactomics Analyses of Wild-Type and Mutant A1CF Reveal Diverged Functions in Regulating Cellular Lipid Metabolism.
J Proteome Res
; 19(10): 3968-3980, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786677
12.
Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells.
Nat Chem Biol
; 14(9): 844-852, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29988067
13.
Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma.
Blood
; 129(16): 2233-2245, 2017 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096095
14.
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.
Nat Chem Biol
; 12(2): 102-8, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26656089
15.
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 475(7355): 231-4, 2011 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21753854
16.
Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 526(7574): 596, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375002
17.
Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.
J Am Chem Soc
; 137(24): 7929-34, 2015 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26042473
18.
Target identification and mechanism of action in chemical biology and drug discovery.
Nat Chem Biol
; 9(4): 232-40, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23508189
19.
Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease.
Commun Biol
; 7(1): 87, 2024 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216744
20.
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Science
; 384(6694): eadk5864, 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38662832