Not Missing the Future: A Call to Action for Investigating the Role of Regenerative Medicine Therapies in Pediatric/Adolescent Sports Injuries.

In August 2016, a group including sport medicine clinicians, researchers, and a bioethicist met in Vail, Colorado to discuss regenerative medicine and its potential role in youth sports injuries. There was consensus that a call to action is urgently needed to understand the current evidence base, the risks and rewards, and future directions of research and clinical practice for regenerative medicine therapies in youth sports. We present here a summary of our meeting, which was supported by the National Youth Sports Health and Safety Institute (NYSHSI), a partnership between the American College of Sports Medicine (ACSM) and Sanford Health. The group's goal is to educate practitioners and the public, and to pioneer a means of accumulating meaningful clinical data on regenerative medicine therapies in pediatric and adolescent athletes.

Medial patellofemoral ligament: anatomy, injury and treatment in the adolescent knee.

PURPOSE OF REVIEW: Traumatic and nontraumatic patellofemoral instability (PFI) in children and adolescents is a complex problem. It is determined by a large number of mechanical and pathomorphologic conditions, mainly seen in nontraumatic dislocations. RECENT FINDINGS: Although conservative treatment with a short immobilization, followed by early passive motion and isometric quadriceps strengthening, can be considered in real traumatic dislocations without any cartilaginous injury, a surgical intervention should be considered in atraumatic cases. As 90% of PFI are nontraumatic and correlated with skeletal deformities, the redislocation rate is reported to be up to 80% after initial conservative treatment. To optimize the results, the causing disorder for PFI has to be considered imperatively. In addition to bony disorder, further risk factors have to be taken into consideration for determining the optimal time for surgery. As biomechanical and clinical studies have shown the importance of the medial patellofemoral complex, especially the medial patellofemoral ligament (MPFL), against patellar lateralization, the reconstruction or minimally invasive double-bundle reconstruction of the MPFL is the main surgical technique to treat PFI in children, as it can be used even in open epiphysial cartilage. Further surgical interventions correcting bone deformities, such as trochleoplasty or tibial tubercle osteotomies addressing lower limb deformities, should be performed after closure of the epiphysial cartilage. SUMMARY: It is the goal of this overview to explain the pathoanatomy of PFI, the demanding clinical and radiological examinations and treatment options.

Arthroscopic anatomical reconstruction of the acromioclavicular joint.

Traditional techniques for restoration of a separated acromioclavicular joint are afflicted with various complications and often lead to recurrent dislocation. Lately, anatomic as well as minimally-invasive repair techniques with major focus on restoration of the coracoclavicular ligaments have been described for acromioclavicular joint reconstruction. We present a technique for an arthroscopically-assisted anatomical acromioclavicular joint reconstruction by replacing the conoid and trapezoid separately with nonabsorbable sutures and titanium buttons.

Guidelines for Treatment of Lateral Patella Dislocations in Skeletally Mature Patients.

The incidence of lateral patella dislocations is high, particularly in young females. Beside traumatic cases, many patients present with specific anatomical factors that predispose to lateral patella dislocations (torsional abnormalities of the femur or the tibia, trochlea dysplasia, patella alta, etc). It is of utmost importance to correct those pathologic factors during concomitant procedures as isolated reconstructions of the medial patellofemoral ligament would fail in the presence of severe anatomic risk factors. This article provides a comprehensive instruction on how to analyze the risk factors for lateral patella dislocation (anatomy, physical examination, imaging) and reports the authors' favorite surgical techniques. Moreover, treatment algorithms are provided for primary and recurrent cases of lateral patella dislocation.

Increased internal femoral torsion can be regarded as a risk factor for patellar instability - A biomechanical study.

BACKGROUND: Increased internal femoral torsion is regarded as a risk factor for patellar instability. Biomechanical investigations confirming this hypothesis are missing. METHODS: Eight fresh-frozen cadaver knees were tested on a specially designed simulator. Patellar motion and patellofemoral pressure were evaluated for 0°, 10°, and 20° of increased internal and external femoral torsion with native and with transected medial patellofemoral ligaments used to simulate patellar instability. A regression analysis was used for statistical analysis. FINDINGS: In native medial patellofemoral ligaments, there were no significant changes in mean or peak pressures for any torsional states (P≥0.07). At 20° increased internal femoral torsion, there was a significant center of force shift towards the lateral side (P=0.01). Patellar shift was directed laterally at low knee flexion angles up to 30°. Lateral patellar tilt increased significantly at 10° and 20° of increased internal femoral torsion (P≤0.004). In transected medial patellofemoral ligaments, mean pressure (P≤0.005) and peak pressure (P≤0.02) decreased significantly for all torsional states. There was a significantly greater lateral center of force shift with increased internal femoral torsion (P≤0.04). Lateral patellar tilt increased significantly (P<0.001). Patellar shift did not change significantly with increased internal femoral torsion (P≥0.30). INTERPRETATION: In a native medial patellofemoral ligament, 20° of increased internal femoral torsion can be regarded as a significant risk factor for patellar instability. With an insufficient medial patellofemoral ligament, 10° of increased internal femoral torsion already represents a significant risk factor.

The tibial tuberosity-trochlear groove distance; a comparative study between CT and MRI scanning.

CT scan is the gold standard for the measurement of the tibial tuberosity-trochlear groove distance (TTTG). The aim of this study was to evaluate the reliability of the TTTG on MRI compared to CT scan. Twelve knees in 11 patients underwent CT and MRI examination for patellofemoral instability or anterior knee pain. Both the bony and the cartilaginous landmarks of the trochlear groove were used for the measurement of the TTTG. The measurements were performed by two experienced musculoskeletal radiologists. The interrater, intermethod and interperiod reliability was calculated using a restricted maximum likelihood estimation and a Bland-Altman analysis. The mean TTTG referenced on bony landmarks was 14.4+/-5.4 mm on CT scans, and 13.9+/-4.5 mm on MR images. The mean TTTG referenced on cartilaginous landmarks was 15.3+/-4.1 mm on CT scans, and 13.5+/-4.6 mm on MR images. An excellent interrater (82%), intermethods (86%), and interperiod (91%) quantitative reliability was found. TTTG can be determined reliably on MRI using either cartilage or bony landmarks. Additional CT scans are not necessary.