Detalhe da pesquisa
1.
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo.
Mol Ther
; 30(9): 2909-2922, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581938
2.
Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system.
Mol Ther Nucleic Acids
; 35(2): 102175, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38576454
3.
Lipid Nanoparticle Delivery Systems to Enable mRNA-Based Therapeutics.
Pharmaceutics
; 14(2)2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35214130
4.
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels.
Nat Biotechnol
; 39(8): 949-957, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34012094
5.
Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin.
Biochim Biophys Acta
; 1768(5): 1121-7, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17321495
6.
Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations.
Biochim Biophys Acta
; 1758(1): 55-64, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16487476
7.
Antitumor efficacy of bcl-2 and c-myc antisense oligonucleotides in combination with cisplatin in human melanoma xenografts: relevance of the administration sequence.
Clin Cancer Res
; 11(5): 1990-8, 2005 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15756025
8.
Liposome-encapsulated vincristine, vinblastine and vinorelbine: a comparative study of drug loading and retention.
J Control Release
; 104(1): 103-11, 2005 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15866338
9.
Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models.
Clin Cancer Res
; 9(12): 4595-605, 2003 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14555535
10.
Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity.
J Pharm Sci
; 94(5): 1024-38, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15793796
11.
Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL.
J Invest Dermatol
; 122(4): 1042-9, 2004 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15102096
12.
Role of c-myc protein in hormone refractory prostate carcinoma: cellular response to paclitaxel.
Biochem Pharmacol
; 68(5): 923-31, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15294455
13.
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Nat Nanotechnol
; 14(12): 1084-1087, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802031
14.
Rational design of cationic lipids for siRNA delivery.
Nat Biotechnol
; 28(2): 172-6, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20081866
15.
High efficiency entrapment of antisense oligonucleotides in liposomes.
Methods Enzymol
; 387: 171-88, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15172164
16.
Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer.
Prostate
; 67(13): 1475-85, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17654511
17.
Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid.
J Pharmacol Exp Ther
; 312(3): 1020-6, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15525796
18.
In vivo administration of liposomal vincristine sensitizes drug-resistant human solid tumors.
Int J Cancer
; 110(5): 767-74, 2004 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15146568