Detalhe da pesquisa
1.
Co-chaperones of Hsp90 in Plasmodium falciparum and their concerted roles in cellular regulation.
Parasitology
; 141(9): 1177-91, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24560171
2.
Plasmodium falciparum possesses a unique dual-specificity serine/threonine and tyrosine kinase, Pfnek3.
Cell Mol Life Sci
; 69(9): 1523-35, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22116321
3.
Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90.
FASEB J
; 25(11): 3828-37, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21778327
4.
Oral streptococci subvert the host innate immune response through hydrogen peroxide.
Sci Rep
; 12(1): 656, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027607
5.
Regulation of Plasmodium falciparum Pfnek3 relies on phosphorylation at its activation loop and at threonine 82.
Cell Mol Life Sci
; 66(18): 3081-90, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19644735
6.
Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production.
J Ind Microbiol Biotechnol
; 36(5): 619-33, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19277744
7.
Atypical caseinolytic protease homolog from Plasmodium falciparum possesses unusual substrate preference and a functional nuclear localization signal.
Parasitol Res
; 105(6): 1715-22, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19789896
8.
A complete library of amino acid alterations at R306 in Streptomyces clavuligerus deacetoxycephalosporin C synthase demonstrates its structural role in the ring-expansion activity.
Proteins
; 70(3): 739-47, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17729280
9.
Relevant double mutations in bioengineered Streptomyces clavuligerus deacetoxycephalosporin C synthase result in higher binding specificities which improve penicillin bioconversion.
Appl Environ Microbiol
; 74(4): 1167-75, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18083859
10.
Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols.
Phytochemistry
; 69(1): 66-75, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17719613
11.
Pfnek3: an atypical activator of a MAP kinase in Plasmodium falciparum.
FEBS Lett
; 580(26): 6083-92, 2006 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17064692
12.
A relevant in vitro eukaryotic live-cell system for the evaluation of plasmodial protein localization.
Biochimie
; 88(10): 1367-75, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16839657
13.
Differences in biochemical properties of the Plasmodial falcipain-2 and berghepain-2 orthologues: implications for in vivo screens of inhibitors.
FEMS Microbiol Lett
; 249(2): 315-21, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16019160
14.
Molecular cloning and functional characterisation of VanX, a D-alanyl-D-alanine dipeptidase from Streptomyces coelicolor A3(2).
Res Microbiol
; 153(1): 27-32, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-11881895
15.
Deacetoxycephalosporin C synthase isozymes exhibit diverse catalytic activity and substrate specificity.
FEMS Microbiol Lett
; 218(2): 251-7, 2003 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12586400
16.
Designing new ß-lactams: implications from their targets, resistance factors and synthesizing enzymes.
Curr Comput Aided Drug Des
; 7(1): 53-80, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20883204
17.
Structural basis of the radicicol resistance displayed by a fungal hsp90.
ACS Chem Biol
; 4(4): 289-97, 2009 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19236053
18.
Pfnek3 functions as an atypical MAPKK in Plasmodium falciparum.
Biochem Biophys Res Commun
; 361(2): 439-44, 2007 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17662247
19.
Molecular basis for thermal properties of Streptomyces thermovulgaris fumarase C hinge at hydrophilic amino acids R163, E170 and S347.
Appl Microbiol Biotechnol
; 75(2): 329-35, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17245573
20.
Functional analysis, overexpression, and kinetic characterization of pyruvate kinase from Plasmodium falciparum.
Biochem Biophys Res Commun
; 326(1): 188-96, 2005 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-15567170