Detalhe da pesquisa
1.
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Hum Mol Genet
; 26(6): 1115-1132, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104789
2.
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.
Hum Mol Genet
; 25(17): 3654-3675, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27378694
3.
The targetable A1 Huntington disease haplotype has distinct Amerindian and European origins in Latin America.
Eur J Hum Genet
; 25(3): 332-340, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28000697
4.
Huntington disease reduced penetrance alleles occur at high frequency in the general population.
Neurology
; 87(3): 282-8, 2016 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27335115