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Lasers Med Sci ; 29(1): 279-88, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-23649614

RESUMO

The aim of the present study was to assess, by light microscopy and histomorphometry, the repair of surgical fractures fixed with internal rigid fixation (IRF) treated or not with IR laser (λ780 nm, 50 mW, 4 × 4 J/cm(2) = 16 J/cm(2), ϕ = 0.5 cm(2), CW) associated or not to the use of hydroxyapatite and guided bone regeneration. Surgical tibial fractures were created under general anesthesia on 15 rabbits that were divided into 5 groups, maintained on individual cages, at day/night cycle, fed with solid laboratory pelted diet, and had water ad libidum. The fractures in groups II, III, IV, and V were fixed with miniplates. Animals in groups III and V were grafted with hydroxyapatite and GBR technique used. Animals in groups IV and V were irradiated at every other day during two weeks (4 × 4 J/cm(2), 16 J/cm(2) = 112 J/cm(2)). Observation time was that of 30 days. After animal death, specimens were taken, routinely processed to wax, cut and stained with HA and Sirius red, and used for histological assessment. The results of both analyses showed a better bone repair on all irradiated subjects especially when the biomaterial and GBR were used. In conclusion, the results of the present investigation are important clinically as they are suggestive that the association of hydroxyapatite, and laser light resulted in a positive and significant repair of complete tibial fractures treated with miniplates.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas/métodos , Regeneração Tecidual Guiada/métodos , Raios Infravermelhos/uso terapêutico , Terapia com Luz de Baixa Intensidade/métodos , Fraturas da Tíbia/radioterapia , Fraturas da Tíbia/cirurgia , Animais , Regeneração Óssea/efeitos da radiação , Substitutos Ósseos , Terapia Combinada , Modelos Animais de Doenças , Durapatita , Masculino , Coelhos , Fraturas da Tíbia/patologia
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