Detalhe da pesquisa
1.
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation.
Nucleic Acids Res
; 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587201
2.
CK2 activity is crucial for proper glucagon expression.
Diabetologia
; 67(7): 1368-1385, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503901
3.
Loss of RREB1 in pancreatic beta cells reduces cellular insulin content and affects endocrine cell gene expression.
Diabetologia
; 66(4): 674-694, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36633628
4.
Loss of tetraspanin-7 expression reduces pancreatic ß-cell exocytosis Ca2+ sensitivity but has limited effect on systemic metabolism.
Diabet Med
; 39(12): e14984, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36264270
5.
Insulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human ß-cells.
J Biol Chem
; 289(46): 32109-32120, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288806
6.
SUMO1 enhances cAMP-dependent exocytosis and glucagon secretion from pancreatic α-cells.
J Physiol
; 592(17): 3715-26, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24907310
7.
SUMOylation protects against IL-1ß-induced apoptosis in INS-1 832/13 cells and human islets.
Am J Physiol Endocrinol Metab
; 307(8): E664-73, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25139051
8.
A role and mechanism for redox sensing by SENP1 in ß-cell responses to high fat feeding.
Nat Commun
; 15(1): 334, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184650
9.
Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease.
medRxiv
; 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38496562
10.
Modulation of insulin secretion by RBFOX2-mediated alternative splicing.
Nat Commun
; 14(1): 7732, 2023 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38007492
11.
A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.
Nat Genet
; 55(1): 54-65, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543916
12.
Impacts of the COVID-19 pandemic on a human research islet program.
Islets
; 14(1): 101-113, 2022 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285768
13.
Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress.
Sci Adv
; 8(40): eabo3932, 2022 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36197983
14.
Yield, cell composition, and function of islets isolated from different ages of neonatal pigs.
Front Endocrinol (Lausanne)
; 13: 1032906, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36619563
15.
Zmiz1 is required for mature ß-cell function and mass expansion upon high fat feeding.
Mol Metab
; 66: 101621, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36307047
16.
Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.
Cell Metab
; 34(2): 256-268.e5, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108513
17.
ß-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet-Fed Mice.
Diabetes
; 70(11): 2626-2638, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34462260
18.
Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes.
Elife
; 102021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34787082
19.
Improved glucose tolerance with DPPIV inhibition requires ß-cell SENP1 amplification of glucose-stimulated insulin secretion.
Physiol Rep
; 8(8): e14420, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32339440
20.
A glucose-dependent spatial patterning of exocytosis in human ß-cells is disrupted in type 2 diabetes.
JCI Insight
; 52019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085831