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1.
Cureus ; 16(4): e58619, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38770452

RESUMO

Background Malnutrition in children continues to be a serious public health problem in India. Therefore, this study aims to evaluate the prevalence of malnutrition and assess factors contributing to it in children of the marginalized slum population of India, masked in the metropolitan cities.  Methods A retrospective data analysis with a cross-sectional model was conducted by medical volunteers affiliated with the Rotaract Club of Medicrew who had organized a free pediatric health check-up camp in the Dharavi village of Mumbai, India for children under five. Children under five years of age group of either sex residing in the slums of Dharavi and whose parents consented are included in the study. Neonates, children older than five years of age, and children whose parents did not consent for them to be included in the study were excluded. A pretested, pre-validated questionnaire was administered, and statistical analysis was done with p-values <0.05 considered to be statistically significant. Results  A total of 126 children were included. Out of these children, 109 of them (86.50%) had a mid-arm circumference of more than 12.5 cm (normal), 11 (8.73%) were between 11.5 cm and 12.5 cm (moderate acute malnutrition), and five (4.77%) were less than 11.5 cm (severe acute malnutrition). Among the 126 kids, 86 kids were above the age of two and their BMI was assessed, 36 (44.19%) were found to be underweight (<5th percentile) while 14 (16.3%) were obese (>95th percentile), and four (4.65%) were overweight (85th-95th percentile). For 106 (84.13%) of these children, the caregivers were mothers while others were fathers (n=4; 3.18%), grandmothers (n=5; 3.97%), sisters (n=5; 3.97%), and aunts (n=6; 4.76%). Out of those who had commenced receiving formal education, only 39 (55.71%) were in an appropriate grade for their age. The mean expenditure on food as a proportion of the total household income was 36.40% (standard deviation (SD) 15.0%). On the single-item sleep quality scale, the sleep of only 36 kids (28.58%) was reported by their caregivers as excellent. A high proportion of other medical problems were reported in the children. Conclusion Our study reports a substantial burden of malnutrition among children residing in the slums of Dharavi. Rigorous strengthening and conceptualization of on-ground nutritional programs targeted toward slum children should be done by Indian healthcare policymakers.

2.
Lung India ; 39(6): 562-570, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36629236

RESUMO

A once often neglected virus from common practice has been demanding the attention of all researchers for the past decade ever since it started to infect humans from its usual wild habitats. The severe acute respiratory syndrome coronavirus 2 infection in humans is now found to have frequent manifestations of thromboembolic events as a result of a hyper-coagulable state. Anti-coagulants (ACs) have been suggested to overcome such a state, and studies have been conducted to assess its role. The objective of this meta-analysis is to determine the existence of such a role and its nature, either beneficial or not, and to assess the strength of this role if it exists. We have conducted an online search in the databases such as PubMed, Google scholar, Lancet, Elsevier, JAMA, Medline, and so on and concluded ten studies among 2562 that had results which were more precise and of better quality. The results of six studies favored the use of ACs, whereas one study showed no beneficial response and four studies discussed the effects of therapeutic versus prophylactic anti-coagulation. The result of our statistical analysis was that the odds ratio for mortality reduction of ACs in coronavirus disease 2019 (COVID-19) patients is 0.6757 (95% CI; 0.5148 to 0.961) and that for benefits of therapeutic ACs versus prophylactic ACs in COVID-19 patients is 0.809 (95% CI; 0.6137 to 1.1917). AC was associated with lower mortality and intubation among hospitalised COVID-19 patients. Compared with therapeutic AC, prophylactic AC was associated with lower mortality, although not statistically significant, and lower bleeding risks.

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