Detalhe da pesquisa
1.
New insights into activation and function of the AMPK.
Nat Rev Mol Cell Biol
; 24(4): 255-272, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36316383
2.
GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Nature
; 619(7968): 143-150, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37380764
3.
Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in mice.
J Biol Chem
; 300(2): 105655, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38237682
4.
The phosphorylation of AMPKß1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids.
Proc Natl Acad Sci U S A
; 119(48): e2119824119, 2022 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36409897
5.
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy.
Proc Natl Acad Sci U S A
; 118(37)2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34493662
6.
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site.
J Biol Chem
; 298(5): 101852, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331736
7.
A novel direct adenosine monophosphate kinase activator ameliorates disease progression in preclinical models of Autosomal Dominant Polycystic Kidney Disease.
Kidney Int
; 103(5): 917-929, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36804411
8.
Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.
Biochem J
; 479(12): 1317-1336, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670459
9.
Prostate-Specific Membrane Antigen (PSMA) Expression Predicts Need for Early Treatment in Prostate Cancer Patients Managed with Active Surveillance.
Int J Mol Sci
; 24(22)2023 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38003213
10.
Increased gut serotonin production in response to bisphenol A structural analogs may contribute to their obesogenic effects.
Am J Physiol Endocrinol Metab
; 323(1): E80-E091, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35575233
11.
AMPK mediates energetic stress-induced liver GDF15.
FASEB J
; 35(1): e21218, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33337559
12.
AMPK activation by SC4 inhibits noradrenaline-induced lipolysis and insulin-stimulated lipogenesis in white adipose tissue.
Biochem J
; 478(21): 3869-3889, 2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668531
13.
The gut microbiome regulates host glucose homeostasis via peripheral serotonin.
Proc Natl Acad Sci U S A
; 116(40): 19802-19804, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527237
14.
Impact of pesticide exposure on adipose tissue development and function.
Biochem J
; 477(14): 2639-2653, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32726435
15.
Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.
Biochem J
; 477(8): 1373-1389, 2020 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32215608
16.
The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice.
Biochem J
; 477(12): 2347-2361, 2020 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32510137
17.
Sevoflurane-induced hyperglycemia is attenuated by salsalate in obese insulin-resistant mice.
Can J Anaesth
; 68(7): 972-979, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33580878
18.
The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK.
J Lipid Res
; 61(3): 387-402, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31964763
19.
AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.
Blood
; 132(11): 1180-1192, 2018 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018077
20.
Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia.
Biochem J
; 476(24): 3687-3704, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782497