Detalhe da pesquisa
1.
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.
Cell
; 186(24): 5220-5236.e16, 2023 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37944511
2.
Manipulating the 3D organization of the largest synthetic yeast chromosome.
Mol Cell
; 83(23): 4424-4437.e5, 2023 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37944526
3.
Systematic analysis of the IL-17 receptor signalosome reveals a robust regulatory feedback loop.
EMBO J
; 39(17): e104202, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32696476
4.
Dissecting the heritable risk of breast cancer: From statistical methods to susceptibility genes.
Semin Cancer Biol
; 72: 175-184, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32569822
5.
Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.
J Med Genet
; 58(6): 392-399, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32591342
6.
PyGNA: a unified framework for geneset network analysis.
BMC Bioinformatics
; 21(1): 476, 2020 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33092528
7.
Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae.
Proc Natl Acad Sci U S A
; 114(8): E1470-E1479, 2017 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28174266
8.
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes.
Genome Res
; 26(1): 36-49, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26566658
9.
Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes.
Proc Natl Acad Sci U S A
; 112(6): 1803-8, 2015 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25624482
10.
BioPartsDB: a synthetic biology workflow web-application for education and research.
Bioinformatics
; 32(22): 3519-3521, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27412090
11.
BioPartsBuilder: a synthetic biology tool for combinatorial assembly of biological parts.
Bioinformatics
; 32(6): 937-9, 2016 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26568632
12.
Biofoundry-Scale DNA Assembly Validation Using Cost-Effective High-Throughput Long-Read Sequencing.
ACS Synth Biol
; 13(2): 683-686, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329009
13.
Context-dependent neocentromere activity in synthetic yeast chromosome VIII.
Cell Genom
; 3(11): 100437, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020969
14.
Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration.
Cell Genom
; 3(11): 100435, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020970
15.
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains.
Cell Genom
; 3(11): 100419, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020974
16.
Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function.
Cell Genom
; 3(11): 100439, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020967
17.
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Cell Genom
; 3(11): 100418, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020971
18.
Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects.
Cell Genom
; 3(11): 100379, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38020977
19.
Identification of sensitive enzymes in the photosynthetic carbon metabolism.
Adv Exp Med Biol
; 736: 441-59, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22161345
20.
Computer Aided Assembly and Verification of Synthetic Chromosomes.
Methods Mol Biol
; 2189: 169-181, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33180301