Detalhe da pesquisa
1.
Investigations on substituted (2-aminothiazol-5-yl)(imidazo[1,2-a]pyridin-3-yl)methanones for the treatment of Alzheimer's disease.
Bioorg Med Chem
; 36: 116091, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33676335
2.
Pharmacological investigation of quinoxaline-bisthiazoles as multitarget-directed ligands for the treatment of Alzheimer's disease.
Bioorg Chem
; 89: 102992, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31174042
3.
Beneficial effects of swertiamarin on dyslipidaemia in streptozotocin-induced type 2 diabetic rats.
Phytother Res
; 26(8): 1259-61, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22228612
4.
Design, synthesis and evaluation of novel 2-thiophen-5-yl-3H-quinazolin-4-one analogues as inhibitors of transcription factors NF-kappaB and AP-1 mediated transcriptional activation: Their possible utilization as anti-inflammatory and anti-cancer agents.
Bioorg Med Chem
; 18(7): 2796-808, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20335039
5.
2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists.
Bioorg Med Chem
; 18(6): 2195-2203, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188574
6.
Design, synthesis and pharmacological evaluation of novel tetrasubstituted thiophene analogues as anti-inflammatory agents.
J Enzyme Inhib Med Chem
; 23(6): 819-28, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18608741
7.
Synthesis, anti-inflammatory, analgesic and antioxidant activities of some tetrasubstituted thiophenes.
J Enzyme Inhib Med Chem
; 23(6): 829-38, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18618323
8.
Thiazolyl-thiadiazines as Beta Site Amyloid Precursor Protein Cleaving Enzyme-1 (BACE-1) Inhibitors and Anti-inflammatory Agents: Multitarget-Directed Ligands for the Efficient Management of Alzheimer's Disease.
ACS Chem Neurosci
; 9(7): 1663-1679, 2018 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29697965
9.
Syntheses of new tetrasubstituted thiophenes as novel anti-inflammatory agents.
Eur J Med Chem
; 42(8): 1049-58, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17336429
10.
Stability-indicating assay method for determination of actarit, its process related impurities and degradation products: Insight into stability profile and degradation pathwaysâ.
J Pharm Anal
; 4(6): 374-383, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29403903
11.
New insight into adenosine receptors selectivity derived from a novel series of [5-substituted-4-phenyl-1,3-thiazol-2-yl] benzamides and furamides.
Eur J Med Chem
; 63: 924-34, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685887
12.
Synthesis and evaluation of quinazolinone derivatives as inhibitors of NF-kappaB, AP-1 mediated transcription and eIF-4E mediated translational activation: inhibitors of multi-pathways involve in cancer.
Eur J Med Chem
; 45(9): 3558-63, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20557982
13.
Antihyperlipidaemic activity of swertiamarin, a secoiridoid glycoside in poloxamer-407-induced hyperlipidaemic rats.
J Nat Med
; 63(4): 437-42, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19633811
14.
Swertiamarin: a lead from Enicostemma littorale Blume. for anti-hyperlipidaemic effect.
Eur J Pharmacol
; 617(1-3): 108-12, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19577561
15.
QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization.
Bioorg Med Chem
; 13(4): 1275-83, 2005 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15670936
16.
Tetra substituted thiophenes as anti-inflammatory agents: exploitation of analogue-based drug design.
Bioorg Med Chem
; 13(24): 6685-92, 2005 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16125391
17.
Design, synthesis, and pharmacological evaluation of some 2-[4-morpholino]-3-aryl-5-substituted thiophenes as novel anti-inflammatory agents: generation of a novel anti-inflammatory pharmacophore.
Bioorg Med Chem
; 12(17): 4667-71, 2004 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15358292
18.
Novel drug designing approach for dual inhibitors as anti-inflammatory agents: implication of pyridine template.
Biochem Biophys Res Commun
; 301(1): 183-6, 2003 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12535659