Detalhe da pesquisa
1.
Synthesis and biological evaluation of tricyclic anilinopyrimidines as IKKbeta inhibitors.
Bioorg Med Chem Lett
; 20(12): 3821-5, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20471256
2.
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
J Med Chem
; 51(12): 3388-413, 2008 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18498150
3.
Inhibition of cytosolic phospholipase A2alpha: hit to lead optimization.
J Med Chem
; 49(1): 135-58, 2006 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16392799
4.
Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.
J Med Chem
; 49(15): 4623-37, 2006 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-16854068
5.
IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model.
Cancer Res
; 68(22): 9519-24, 2008 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010928
6.
Cyclic amine sulfonamides as linkers in the design and synthesis of novel human beta(3) adrenergic receptor agonists.
Bioorg Med Chem Lett
; 13(13): 2191-4, 2003 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12798332
7.
Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists.
Bioorg Med Chem Lett
; 13(13): 2195-8, 2003 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12798333