Detalhe da pesquisa
1.
Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.
Mol Cell
; 82(13): 2458-2471.e9, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35550257
2.
Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding.
Am J Hum Genet
; 110(3): 427-441, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787739
3.
ERG transcription factors have a splicing regulatory function involving RBFOX2 that is altered in the EWS-FLI1 oncogenic fusion.
Nucleic Acids Res
; 49(9): 5038-5056, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34009296
4.
The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cells expansion.
Haematologica
; 107(1): 268-283, 2022 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33241676
5.
Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.
EMBO Rep
; 20(12): e48375, 2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668005
6.
Systematic identification of genomic markers of drug sensitivity in cancer cells.
Nature
; 483(7391): 570-5, 2012 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22460902
7.
Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis.
Nucleic Acids Res
; 41(19): 8853-71, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935076
8.
Functional Classification of Fusion Proteins in Sarcoma.
Cancers (Basel)
; 16(7)2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611033
9.
Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer.
Mol Cancer Ther
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471796
10.
Simple droplet microfluidics platform for drug screening on cancer spheroids.
Lab Chip
; 23(24): 5139-5150, 2023 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37942508
11.
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma.
Cancer Lett
; 554: 216028, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36462556
12.
VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis.
Cell Rep
; 42(1): 112013, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36656711
13.
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Sci Adv
; 9(6): eade9238, 2023 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36753540
14.
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution.
Nat Commun
; 14(1): 8361, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102136
15.
SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance.
Nat Commun
; 14(1): 3034, 2023 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37236926
16.
Combination Therapies Targeting ALK-aberrant Neuroblastoma in Preclinical Models.
Clin Cancer Res
; 29(7): 1317-1331, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36602782
17.
Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma.
Nat Commun
; 14(1): 2575, 2023 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37142597
18.
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors.
Commun Biol
; 6(1): 949, 2023 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37723198
19.
Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups.
Nat Commun
; 14(1): 6669, 2023 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863903
20.
De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis.
Nucleic Acids Res
; 38(11): e126, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20375099