The impact of rotavirus vaccination on acute diarrhea in Thai children under 5 years of age in the first year of universal implementation of rotavirus vaccines in the National Immunization Program (NIP) in Thailand: a 6-year analysis.

BACKGROUND: Two types of rotavirus vaccines (RVs), Rotarix (RV1) and RotaTeq (RV5), were licensed as optional vaccines in 2012 and became part of the National Immunization Program (NIP) in the fiscal year 2020 in Thailand. The main objective was to evaluate the impact of rotavirus vaccines on the burden of acute diarrheal severity ranging from outpatient visits, diarrheal-related admission or deaths in the pre-NIP period (fiscal year 2015-2019) and in the fiscal year 2020. The minor objectives were assessed on the monthly admission rate, rotavirus vaccine coverage rate and rotavirus vaccine completed dose (RotaC). METHODS: Data regarding OPD, admission, and death cases under the Thailand National Health Coverage (NHC) from fiscal year 2015-2020, which were recorded as International Classification of Diseases and Related Health Problem 10th (ICD-10), were analyzed. RESULTS: The burden of diarrheal-related disease diminished after the rotavirus vaccine was introduced in the fiscal year 2020 when compared to the previous 5 fiscal years. The OPD visit rate decreased from 10.1 to 8.3 visits per 100 person-years (P < 0.001), or a 17.8% reduction (incidence rate ratio (IRR) = 0.82; 95% confidence interval (CI): 0.81 to 0.82). The admission rate significantly declined from 31.4 to 30.5 cases per 1,000 person-years, (P < 0.001), or a 2.9% reduction (IRR = 0.97; 95% CI: 0.96 to 0.98). The diarrheal-related mortality rate also subsided from 10.2 to 8.1 cases per 100,000 person-years (P 0.3), or a 20.0% reduction (IRR = 0.88; 95% CI: 0.50 to 1.22). The major population in both admissions and deaths was infants under 1 year of age (P < 0.001). Seasonality was seen as a constant bimodal pattern, with a significant decrease in monthly admissions after 6 months of rotavirus vaccine introduction to NIP (P < 0.001). RotaC was 37.4% in the first year of NIP. CONCLUSIONS: The rotavirus vaccine had a potential benefit for reducing the diarrheal disease burden, especially in infants under one year of age. Seasonality outbreaks of acute diarrhea subsided after the rotavirus vaccine was introduced. The RotaC was fairly low in the first year of the NIP. The quality of the rotavirus vaccine should be warranted. TRIAL REGISTRATION: Number TCTR20220120003 , date of registration: 20/01/2022, site: Thai Clinical Trials Registry.

Effectiveness of a Mobile App (KhunLook) Versus the Maternal and Child Health Handbook on Thai Parents' Health Literacy, Accuracy of Health Assessments, and Convenience of Use: Randomized Controlled Trial.

BACKGROUND: Children of parents who have higher health literacy (HL) benefit more from preventive child health care. Digital interventions have been used to improve parents' HL with high satisfaction. KhunLook is a Thai mobile app conceived using strategies to improve HL. It was developed to assist parents in assessing and keeping track of their child's health in complement to the standard Maternal and Child Health Handbook (MCHH). OBJECTIVE: This trial focuses on the effectiveness of using the KhunLook app with the MCHH and standard care (intervention) compared with the conventional MCHH and standard care (control) on parents' HL. Data on accuracy of parents' assessment of their child's health and growth as well as convenience of use of the tool (app or MCHH) in the well-child clinic were collected at 2 visits (immediate=visit 1, and intermediate=visit 2). METHODS: Parents of children under 3 years of age who (1) had a smartphone or tablet and the MCHH and (2) could participate in 2 visits, 2-6 months apart at Srinagarind Hospital, Khon Kaen, Thailand, were enrolled in this 2-arm parallel randomized controlled trial between April 2020 and May 2021. Parents were randomized 1:1 to 2 groups. At visit 1, data on demographics and baseline HL (Thailand Health Literacy Scales) were collected. Parents in the app group used the KhunLook app and the control group used their child's handbook to assess their child's growth, development, nutrition and feeding, immunization status and rated the convenience of the tool they used. At visit 2, they repeated the assessments and completed the HL questionnaire. RESULTS: A total of 358 parents completed the study (358/408, 87.7%). After the intervention, the number of parents with high total HL significantly increased from 94/182 (51.6%) to 109/182 (59.9%; 15/182; Δ 8.2%; P=.04), specifically in the health management (30/182; Δ 16.4%; P<.001) and child health management (18/182; Δ 9.9%; P=.01) domains in the app group, but not in the control group. Parents in the app group could correctly assess their child's head circumference (172/182, 94.5% vs 124/176, 70.5%; P<.001) and development (173/182, 95.1% vs 139/176, 79.0%; P<.001) better than those in the control group at both visits. A higher proportion of parents in the app group rated their tool as very easy or easy to use (174-181/182, 95.6%-99.5% vs 141-166/176, 80.1%-94.3%; P<.001) on every item since the first visit. CONCLUSIONS: Our results suggest the potential of a smartphone app (KhunLook) to improve parents' HL as well as to promote superior accuracy of parents' assessment of their child's head circumference and development, with a similar effect on weight, height, nutrition and feeding, and immunization as in traditional interventions. Using the KhunLook app is useful and more convenient for parents in promoting a healthy child preventive care during early childhood. TRIAL REGISTRATION: Thai Clinical Trials Registry TCTR20200312003; https://www.thaiclinicaltrials.org/show/TCTR20200312003.

Burden and pattern of acute diarrhea in Thai children under 5 years of age: a 5-year descriptive analysis based on Thailand National Health Coverage (NHC) data.

BACKGROUND: The incidence of acute diarrhea in Thai children under five years of age has increased over the last three decades. Even though mortality has significantly declined, the burden and cost of medical treatment are still high. Our objectives are to describe the burden and pattern of acute diarrhea cases that required admissions by Thai children under five years of age from 2015 to 2019. METHODS: Data regarding the admission of acute diarrhea cases of Thai children with Thailand National Health Coverage (NHC) under five years of age from 2015 to 2019, recorded as International Statistical Classification of Diseases and Related Health Problems, tenth Revision, Thai Modification (ICD-10-TM), were analyzed. RESULTS: The incidence trend of yearly acute diarrhea in children 0-5 years of age slightly increased from 33.36 cases per 1,000 population in 2010 to an average of 33.79 cases per 1,000 population/ year from 2015 to 2019 or approximately 0.43 cases per 1,000 population over the last decade while diarrhea-related mortality had a low, constant rate of 0.71 to 1.16 per 100,000 population per year. Two thirds of the mortality rate was observed in children under 1 year of age or 4.1 cases per 100,000 person-years in 5-year period (P < 0.01). The high cost of performing the medical treatment of approximately four hundred million baht per year. Seasonal variations demonstrated consistency with similar patterns during the cold and rainy seasons throughout the 5-year period. Regional distribution of the causative agent was also observed in Cholera, Typhoid, and Amoebiasis cases. A08: viral and other specified intestinal infections and A09: other gastroenteritis and colitis of infectious and unspecified origin were the two most common causes of diarrheal diseases. CONCLUSIONS: The incidence rate of acute diarrhea in Thai children under five years of age was higher while the mortality rate of acute diarrhea was lower than those in the past decade. A similar seasonal outbreak of acute diarrhea was seen during each examined year. The causative agent was not significant and was mainly unspecific. TRIAL REGISTRATION: Number TCTR20220117002, date of registration: 17/01/2022, site: Thai Clinical Trials Registry, URL http://www.thaiclinicaltrials.org/show/TCTR20220117002.

Burden of adult pneumonia in Thailand: a nationwide hospital admission data 2010.

OBJECTIVE: To quantify the admission mortality, pathogens,factors related to mortality, length of hospital stay, and healthcare costs in adult hospitalized pneumonia in Thailand MATERIAL AND METHOD: The data on hospitalized pneumonia for the 2010 fiscal year extracted from the three main health insurance coverage schemes in Thailand (the Social Security System (SSS), the Medical Welfare System (MWS), and the Civil Servant Medical Benefit System (CSMBS)) were analyzed RESULTS: Adult hospitalized pneumonia admissions numbered 136,696, with mortality rate 9.63%. The mortality increased with increasing age, 15.49% for age > 80 years. Influenza virus was the major etiology for 19 to 25 years old (49.30%) with low mortality (1-2%). S. pneumoniae and typical pathogens were found in every age group. The mortality rate for S. pneumoniae increased with age, viz. 0%, 1.96%, 5.56%, 7.02%, 6.98%, and 24.24% for 19 to 25, 26 to 40, 41 to 60, 61 to 70, 71 to 80, and 81+ years old. The mortality rate from C. pneumonia was about 10% and high among the younger age group. Gram-negative bacilli and Staphylococcus caused high mortality (about 20 to 35%), especially in the older age group. The major risk factors for increasing mortality were: elderly (OR 3.46, 95% CI 3.27-3.77), alcoholic liver disease (OR 3.26, 95% CI 2.85-3.72), cirrhosis (OR 3.45, 95% CI 2.93-4.08), heart disease (OR 2.47, 95% CI 2.38-2.56), ischemic heart disease (OR 2.21, 95% CI 2.07-2.36), renal failure (OR 5.26, 95% CI 5.07-5.49), and cerebrovascular disease (OR 3.62, 95% CI 3.43-3.82). The median length of hospital stay was four days (IQR, 3-7 days) and the median cost of treatment per admission was US$ 256.63 (IQR, US$ 147.81-531.21). Complications such as acute respiratory failure, acute respiratory distress syndrome (ARDS), septicemia, shock, and acute renal failure made hospital stays two to three days longer and costs three to seven times higher than no complications. CONCLUSION: The mortality from pneumonia among the elderly was high, especially for those over 80 and with multiple medical co-morbidities.

The health situation among Thai elementary school-age children: 2010.

BACKGROUND: The school years are a crucial time in the development of the basic life skills necessary for learning in the various and different fields to be encountered in life, as well as for developing and acquiring the knowledge, skills and attitudes necessary to establish and maintain a healthy lifestyle. In general, elementary school-age children rarely present at health service centers but may nevertheless have health problems that affect their ability to learn. OBJECTIVE: To analyze the health situation among elementary school-age children in Thailand, for the creation of baseline information to serve as an evential basis for making recommendations for adjusting the medical education curriculum and for improving health service provision. MATERIAL AND METHOD: To analyze nationwide, hospital data, for the morbidity and mortality of children age 6-12 years in fiscal year 2010. RESULTS: Respiratory infections represented the leading cause for out-patient visits-approximately one-fifth. Respiratory infections were also a significant cause for admissions (21.6%), followed by dengue hemorrhagic fever (14.8%), injury and poisoning (11.3%), disease of digestive system (11.1%) and intestinal infection (10.3%). The leading causes of death were injury and poisoning (22.7%), followed by neoplasm (14.4%), other infection (13.5%) and respiratory infection (12.6%). Overall, about 50-60% of the causes of admissions and of deaths were due to infectious diseases and injury & poisoning. CONCLUSION: Infectious diseases and injury & poisoning were the major physical illnesses among school-age children. Notwithstanding, there were other health issues-including nutrition, growth & development, mental health & psychosocial problems-that need to be recognized and addressed in order to ensure the health and well-being of school-age children in Thailand.

Burden of acute lower respiratory infection in children in Thailand in 2010: have we achieved the national target in under-five morbidity and mortality?

BACKGROUND: National reports indicate that morbidity and mortality from pneumonia among Thai children has decreased dramatically since the turn of the millennia; notwithstanding, pneumonia remains the leading cause of admission and death in Thai children under five years of age. OBJECTIVE: To assess the burden and pattern of acute lower respiratory infection in under-fives in Thailand from the health data in 2010. MATERIAL AND METHOD: Information on respiratory infection using the ICD10: J09-J22 was evaluated for the number of OPD visits, admissions, mortality, monthly incidence and co-morbidities of the mortality. RESULTS: 73% of all OPD visits with ALRI were in under-fives: one-fourth of whom required hospitalization. Pneumonia is the leading cause of both admissions and mortality (3.22% and 11.29/100,000 population for this age group, respectively). The highest mortality was in the first year of life (39/100,000). One-fourth of the children (168/639) died within 24 hours of admission and septicemia was the most common co-morbidity. CONCLUSION: The respective morbidity and mortality of pneumonia in under-fives fell far short of national targets. To achieve these targets, many key aspects are needed; such as, strengthening the knowledge of healthcare personnel, the cost-effectiveness researches on the causative organism detection and the expanding coverage of the preventable-vaccine.

Burden of acute, persistent and chronic diarrhea, Thailand, 2010.

BACKGROUND: The incidence of diarrhea in Thai children under five years of age increased over the last decade while mortality dramatically decreased. To evaluate the effectiveness of MCH services under Universal Coverage Schemes, health outcomes should be performed. OBJECTIVE: To assess the burden and pattern of childhood diarrheal diseases in Thai children under five. MATERIALS AND METHOD: The information on Intestinal Infectious Diseases ICD10: A00-A09 was divided into two groups: 1. Infectious diarrhea: A04, A05, A08, A09 and 2. Dysentery: A02, A03. The authors investigated the number of OPD visits, IPD, mortality, length of hospital stay and co-morbidity of severe cases. RESULTS: The burden of diarrhea was: 3.7 million (1:1) episodes, 756,552 OPD visits (1:5), 124, 403 IPD admissions (1:30), 202 (1:18,460) persistent diarrhea and 48 (1:77, 685) deaths. Diarrheal incidence had two peaks: cool season and early rainy season. Admissions lasted a collective 309,398 days. Diarrhea was persistent in 202 episodes (1.6 per 1,000 admissions) and the associated factors included: age, sepsis, anemia, chronic diseases, malnutrition and HIV. The risks for diarrhea-related mortality included: infant, septicemia and dehydration. CONCLUSION: The incidence of diarrhea was higher than expected albeit mortality was low. The mortality rate was associated with age under one year persistent diarrhea, septicemia, chronic and underlying diseases.

Dengue mortality in patients under 18 years old: an analysis from the health situation analysis of Thai population in 2010 project.

BACKGROUND: Dengue is an important cause of morbidity and mortality in tropical and subtropical regions of the world. In Thailand, there has been no detailed research on mortality in children in terms of duration of admission and associated complications in the cases that died. OBJECTIVE: To assess the burden of dengue in Thailand in 2010 and to analyze the complications in patients aged under 18 years who died. MATERIAL AND METHOD: The authors described the mortality and complications of dengue fever and dengue hemorrhagic fever in patients under 18 years old using the information from the Health Situation Analysis of the Thai Population 2010 Project. RESULTS: In 2010, the overall mortality of dengue in all age groups and in patients aged under 18 years were 0.3 and 0.6/ 100,000, respectively. The mortality rate was highest among children aged 6-12 years (0.8/100,000). Among the 8 children with dengue fever that died, the 2 most common complications were fluid electrolyte and acid-base imbalance and disseminated intravascular coagulation (DIC). The common complications among the 91 cases with dengue hemorrhagic fever that died included fluid electrolyte and acid-base imbalance, hepatic failure, respiratory failure, bacterial infection, DIC and renal failure. CONCLUSION: Early diagnosis, careful management of fluid therapy, awareness of hepatic and renal impairment and early treatment of co-infection should decrease mortality of dengue hemorrhagic fever

Childhood neoplasms: analysis of Thai children 2010.

BACKGROUND: Between 1990 and 2010, many national and international factors converged to both beneficially and antagonistically affect people's health as well as the Thai healthcare system. Among these were: a falling birth rate in Thailand and a gradual decline in poverty-related diseases. Cancer becomes the most common cause of death. OBJECTIVE: To analyze Thailand's childhood neoplasm issues for baseline information for changing medical education, services and research. MATERIAL AND METHOD: Information on the illnesses of in-patients, out-patients and casualties was based on hospital withdrawals nationwide from the three health insurance schemes in the fiscal year 2010. The data, which included 96% of the population, were analyzed by age groups and burden of neoplasm disease. RESULTS: The children with neoplasms were treated 127,597 times at outpatient departments (OPD) and 19,159 times at inpatient departments (IPD) at community hospitals (4.3%), provincial hospitals (8.50%), regional or university hospitals (86.1%) and private hospitals (1.1%). Malignant neoplasms of lymphoid hematopoietic and related tissues were the most common in both IPD and OPD settings, which resulted in the highest cost of treatment. Tumors of the central nervous system were associated with the highest cost. The mean length of stay for all patients with neoplasm was 7.85 days. CONCLUSION: Sufficient budget should be allocated to the more heavily frequented treatment center Specific and better care, national treatment protocols for each type of childhood cancer (including palliative care) should be developed to improve the treatment outcomes and/or the quality of life. Medical schools and health service systems need to be recalibrated to respond proactively to these changes being experienced by the healthcare system.

Coronary artery disease in the Thai population: data from health situation analysis 2010.

BACKGROUND: The rate of cardiovascular disease marked by coronary artery disease (CAD) is increasing in low-middle income countries including Thailand. The burden of CAD will have a significant impact on the healthcare system and the national budget. OBJECTIVE: To identify the CAD-related hospitalization rate over one year; to determine in-hospital mortality in various subgroups of patients with CAD and to examine the hospitalization costs of patients with CAD. MATERIAL AND METHOD: The data were extracted from in-patient discharge forms from the three main health insurance schemes in Thailand for the fiscal year 2010 (October 1, 2009 to September 30, 2010. The data included the three major health insurance schemes which provided coverage for about 62 million people (96% of the population). Data regarding coronary artery disease using the ICD-10 (I20-angina, I21-acute myocardial infarction (AMI) and I25-chronic ischemic heart disease) were extracted and analyzed for number of admissions, mortality rate, length of hospital stay and hospital charges. RESULTS: In 2010, the total admissions of patients with coronary artery disease were 22,507. The most common presentation of CAD was angina pectoris (10,822 admissions)followed by AMI (6,391 admissions) and chronic ischemic heart disease (5,294 admissions). The respective in-hospital mortality rates in patients admitted with AMI, chronic ischemic heart disease and angina pectoris were 11.3%, 2.9% and 0.7%. CONCLUSION: Thailand is entering a period of epidemiologic transition marked by an increase of cardiovascular disease and hospital expenses dominated by cardiovascular disease. Information on the burden of CAD--indicates a need to improve health care system.

From health situation to health education and health service reforms for Thai society.

BACKGROUND: Health problems and service utilization patterns among Thai populations have changed significantly over the past three decades. It is imperative to scrutinize the changes so that the health service and human resource development systems can appropriately respond to the changing health needs. OBJECTIVE: To synthesize critical issues for future planning of health service reforms, medical education reforms and health research for Thai society. MATERIAL AND METHOD: The authors analyzed data on health service utilization, types of illnesses and hospital deaths among Thais in the fiscal year 2010. Information on the illnesses of in-/out-patients and hospital deaths was extracted from the three main health insurance schemes providing coverage to 96% of the population. The authors then synthesized the key issues for reforming medical education and health services. RESULTS: In summary, Thai patients have better access to health services. The total number of out-patient visits was 326,230,155 times or 5.23 visits per population. The total number of in-patient admissions was 6,880,815 times or 0.11 admissions per population. The most frequent users were between 40-59 years of age. The most common conditions seen at OPD and IPD and the causes of in-hospital mortality varied between age-groups. The key health issues identified were: psychosocial conditions, health behaviour problems, perinatal complications, congenital malformations, teenage pregnancy, injury, infectious diseases, cardiovascular diseases and neoplasms. Medical education reforms need to be designed in terms of both undergraduate and post-graduate education and/or specialty clinical needs. Health service reforms should be designed in terms of patient care systems, roles of multidisciplinary teams and community involvement. CONCLUSION: The government and other responsible organizations need to actively respond by designing the health service systems and human resource development systems that are relevant, appropriate and integrated. Different levels of care need to work collaboratively in order to achieve the greatest quality and efficiency.

Current challenges in reducing neonatal morbidity and mortality in Thailand.

BACKGROUND: Information on neonatal mortality and burden of illness during the neonatal period is an essential guide for prioritizing interventions for solving health problems and allocating resources. OBJECTIVE: To evaluate the burden of diseases and the current health situation among Thai neonates under the Universal Health Insurance Coverage Scheme. MATERIALS AND METHOD: The number of admissions according to mortality, length of hospital stay and cost of hospital charges during the neonatal period was analyzed. RESULTS: There were 638,795 live births according to the data extracted from the three healthcare schemes supporting universal healthcare' in Thailand, which is lower than the data from the Health Information Unit of the Bureau of Health Policy and Strategy at the Ministry of Public Health. The neonatal death rate was 3.98 per 1,000 live births comprising 58.9% of all infant deaths. Major proportion of neonatal deaths (700%) occurred in early neonatal period and 43% of which occurred within the first two days of life. The leading causes of neonatal deaths were prematurity, respiratory problems, congenital malformation, birth asphyxia and infection. The most prevalent diagnosis for admissions was neonatal jaundice, disorders related to short gestation, respiratory disorders and neonatal infection. CONCLUSION: More investment is required to improve education and implement health interventions that can be integrated into existing health systems for better neonatal outcomes.

Health situation analysis of Thai children aged 1-5 years in 2010: implications for health education and health service reform.

BACKGROUND: To make the world fit for children is a task necessarily involves all organizations working with children. The real health situation will be useful for strategic planning for them. OBJECTIVE: To emphasize Thailand's health burdens of children between 1 and 5 years in 2010. MATERIAL AND METHOD: The authors analyzed the fiscal 2010 data from the three health insurance schemes from hospitals nationwide for information on: out-patient and in-patient visits, common illnesses of Thai children between 1 and 5 years, lengths of stay, hospital charges and deaths. Most (96%) of the population was represented in this data. RESULTS: Respiratory infection was the most common admission (225,183 times) while intestinal infection was the second (83,293 times). Respiratory infection was the second most common for an out-patient visit (7, 387,132 times = 23.6%) after other factors influencing health (17,384,963 times = 55.5%). The most common causes of death were injury and poisoning (178 patients) and respiratory infection (175 patients). Pneumonia required the most budget and resulted in the longest stays. Among accidents, accidental drowning and submersion caused the most deaths. CONCLUSION: Respiratory infection, pneumonia, intestinal infection, injuries, poisoning and accidental drowning were the most common health burdens among children between 1 and 5 years of age.

Thailand's adolescent health situation: prevention is the key.

BACKGROUND: Adolescence is generally a period of good physical health, but future health problems may begin at this age due to exposure to risk factors for diseases. OBJECTIVE: To analyze the health situation of adolescents (age 13-18years) in Thailand in order to derive guidance for the refinement and calibration of the medical curriculum and enhance health service provision to adolescents. MATERIAL AND METHOD: National data from Thailand's 3 major health care systems, regarding; the causes of out-patient visits, in-patient admissions and deaths in the fiscal year 2010 were analyzed. RESULTS: The leading causes of out-patient visits were (1) factors influencing health (2) respiratory infections (3) diseases of the digestive system (4) injury and poisoning and (5) external causes of morbidity and mortality. The leading causes of admissions were (1) pregnancy (2) injury and poisoning and (3) arthropod-borne viral fevers. The leading causes of hospital deaths were (1) injury and poisoning (2) neoplasms and (3) other infections. CONCLUSION: The majority of the causes of morbidity and mortality were related to psychosocial factors and engagement in high risk behaviors.

Unintentional injury among Thai children and adolescents in 2010.

BACKGROUND: Unintentional injury has been identified as a public health problem in Thailand as it is the leading cause of death among both children and adolescents. OBJECTIVE: To explore the number of admissions by unintentional injury and cause(s) among Thai children and adolescents in 2010. MATERIAL AND METHOD: Data on the number of admissions by unintentional injury in the fiscal year, 2010, were derived from hospitals nationwide as well as the three health insurance schemes. Data on Thai children and adolescents (0-18 years) was collected between October 1, 2009 and September 30, 2010. The coding for underlying cause(s) of unintentional injuries and death were done using the International Classification of Diseases, 10th edition. RESULTS: A total of 118,323 unintentional injuries were reported. The majority of patients were male and falls were the major cause of unintentional injuries (27,139 admissions; 22.94%) followed by motorcycle injuries (20,499 admissions; 17.32%). Accidental drowning and submersion was the major cause of death in the present study, followed by lightning strikes and accidental threats to breathing (i.e., choking and suffocation). CONCLUSION: The current study revealed that falls were the major cause of unintentional injury and accidental drowning and submersion the major cause of death.

Disease burden of immune thrombocytopenic purpura among adult patients: the analysis of Thailand healthcare databases 2010.

BACKGROUND: Immune thrombocytopenic purpura (ITP) is not rare disease and it ispotentially fatal, particularly in patients with bleeding events which usually lead to hospitalization. Current data on the impact and disease burden of ITP in Thailand are lacking. OBJECTIVE: To determine admission rate, mortality rate, hospital cost, length of hospital stay, co-morbidities, treatment and major bleeding events in patients with ITP. MATERIAL AND METHOD: The authors analyzed the data of inpatients with a diagnosis of ITP according to ICD10 coded D69.3 which were retrieved from a nationwide health financing schemes in fiscal 2010. The data were analyzed by age groups, gender and health financing schemes. RESULTS: The overall admission rate and mortality rate were 7.68 and 0.29 per 100,000 populations, respectively and increased with age. Women were predominant. Average hospital costs and hospital stays were 27,133 Baht and 6.7 days per admission, respectively and slightly higher among men than women. The most common co-morbidity was hypertension. Gastrointestinal hemorrhage was the most common bleeding event which was 21.5 per 1,000 admissions. Patients in the civil servant medical benefit scheme had the highest percentage of high cost treatment accessibility. CONCLUSION: The admission rate, mortality rate and major bleeding events increased with age and was higher among women than men. Average hospital cost and length of hospital stay are higher in men than women. Common co-morbidities may be related to the treatment of ITP There are the differences in high-cost treatment accessibility between health insurance schemes.

Geriatric hospitalizations due to fall-related injuries.

BACKGROUND: Fall is a preventable condition associated with disability and mortality in elders. The overall data regarding admission rates and its impact in Thai elderly are lacking. OBJECTIVE: To identify admission, mortality rates of older persons with fall, its causes and consequences. MATERIAL AND METHOD: Information on illness of inpatients and casualties came from hospitals nationwide and from hospital withdrawals from the 3 health insurance schemes in fiscal 2010. The data included 96% of the population. The data were analyzed by age groups in older patients with fall. RESULTS: There were 311,132 falls of all admissions; accounting for admission and mortality rates of 423.4 and 11.1/100,000 older persons. The number rose with age. Slipping, tripping were the major causes. The average length of stay (LOS) of fallers with and without fractures was 8.1 and 6.4 days. The average hospital costs in these same groups were 25,728 and 19,419.3 Baht. CONCLUSION: The increasing age is related to an increased admission and mortality rates of fall. Slipping, tripping was the frequent causes. Greater LOS and hospital charges were found in fallers with fractures. Allied-healthcare workers should routinely implement a fall assessment and educate modifiable factors to elders to prevent future fall.

Evaluation of causes-of-death: which statistics should we rely on, hospital deaths or vital statistics?

BACKGROUND: Age-specific causes of death yield important information for planning health services and medical education. OBJECTIVE: To compare the age-specific causes of death between in-hospital deaths and death registration statistics. MATERIAL AND METHOD: Information on in-hospital mortality in fiscal 2010 was extracted from the three health insurance schemes. Death registrations (ICD-10 coding) were from the Bureau of Registration Administration, Ministry of Interior Statistics on the age-specific causes of death were analyzed. RESULTS: In-hospital deaths numbered 132,512 (47.5% occurring in tertiary care) vs. 411,331 recorded in vital statistics (68% died outside hospitals). Most (74%) infants died in-hospital so causes were clearly documented vs. death registration. A minority (6.2%) of in-hospital deaths and of death registrations (9.7%) were due to unnatural causes. The majority (79.5%) of unnatural deaths died before arriving at hospital. Ill-defined codes for causes of death were found in 6.1% of in-hospital records and 42.2% of death registrations. After censoring ill-defined codes, the ten leading, age-specific causes of death agreed between the two data sets. CONCLUSION: Medical personnel should receive training to do proper death certification. Periodic validation of hospital COD certification should also be done. Use of verbal autopsy in the Thai context would help to standardize record-keeping and to reduce ill-defined codes for deaths occurred outside hospital.

Health situation analysis of Thai population 2010: implications for health education and health service reform.

BACKGROUND: Between 1990 and 2010, many national and international factors converged to both beneficially and antagonistically affect people's health and the Thai healthcare system. Moreover Thailand is moving to aged society and a low birth rates. OBJECTIVE: To analyze Thailand's health issues for baseline information for changing medical education, services and researches. MATERIAL AND METHOD: Information on illness of in-patients, out-patients and casualties came from hospitals nationwide and from hospitals withdrawals from the three health insurance schemes in fiscal 2010. The data included 96% of the population. Research literature was also extensively reviewed. The data were analyzed by age groups and burdensome diseases. RESULTS: Out-patients were treated 326,230,155 times and in-patients 6,880,815 times at Community Hospitals (44%), Provincial Hospitals (22%), Central or University Hospitals (26%) and Private Hospitals (8%). Infants and elderly were the patients most commonly treated in hospital. Among pediatric patients, perinatal disease, intestinal infection, respiratory tract infection, injury and poisoning and teenage pregnancy predominated; while among adults, it was accident, non-communicable and chronic disease. CONCLUSION: Thailand is faced with the dual burden of infection and non-communicable diseases. Risky behavior and changing social structure are underlined this epidemiological transition. Medical schools and health service systems need to be recalibrated to response proactively to these challenges.

Thai infant health situation: essential medical information for family centered care.

BACKGROUND: The family-centered care requires reliable information on morbidity, mortality and related health problems to educate the responsible families. OBJECTIVE: To explore diseases and deaths of infants aged 29 days-12 months under the 2010 Universal Health Insurance in Thailand. MATERIAL AND METHOD: As per Sutra et al in 'Health situation analysis of Thai population 2010. The data included in the analysis were numbers and percents of primary diagnosis of each visit in the outpatient department (OPD), admitted cases and infant death. Other health related issues were also retrieved from the existing sources of health information at country level. RESULTS: The infants aged 29 days-12 month had 9,721, 266 OPD visits including factors influencing health (69.6%), respiratory infections (16.3%), Intestinal infection (2.4%) and other diseases (11.7%). The admitted cases commonly had respiratory infections (47.5%), intestinal infections (23.4%), other infections (4.8%) and congenital malformation (2.8%). The three most common causes of hospital deaths were perinatal conditions (25.2%), congenital malformation (21.4%) and respiratory infection (18.5%). There were also neonatal problems of low birth weight and iodine deficiency. CONCLUSION: The infectious diseases and perinatal health problems were the main issues for family education in the family centered care to reduce the burden of diseases and infant death.