Pesquisa | BVS Integralidade em Saúde

1.

Lecanemab in Early Alzheimer's Disease.

van Dyck, Christopher H; Swanson, Chad J; Aisen, Paul; Bateman, Randall J; Chen, Christopher; Gee, Michelle; Kanekiyo, Michio; Li, David; Reyderman, Larisa; Cohen, Sharon; Froelich, Lutz; Katayama, Sadao; Sabbagh, Marwan; Vellas, Bruno; Watson, David; Dhadda, Shobha; Irizarry, Michael; Kramer, Lynn D; Iwatsubo, Takeshi.

N Engl J Med ; 388(1): 9-21, 2023 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-36449413

2.

A Nuclear Export Signal in KHNYN Required for Its Antiviral Activity Evolved as ZAP Emerged in Tetrapods.

Lista, Maria J; Ficarelli, Mattia; Wilson, Harry; Kmiec, Dorota; Youle, Rebecca L; Wanford, Joseph; Winstone, Helena; Odendall, Charlotte; Taylor, Ian A; Neil, Stuart J D; Swanson, Chad M.

J Virol ; 97(1): e0087222, 2023 01 31.

Artigo em Inglês | MEDLINE | ID: mdl-36633408

3.

Strain-Dependent Restriction of Human Cytomegalovirus by Zinc Finger Antiviral Proteins.

Lista, Maria Jose; Witney, Adam A; Nichols, Jenna; Davison, Andrew J; Wilson, Harry; Latham, Katie A; Ravenhill, Benjamin J; Nightingale, Katie; Stanton, Richard J; Weekes, Michael P; Neil, Stuart J D; Swanson, Chad M; Strang, Blair L.

J Virol ; 97(3): e0184622, 2023 03 30.

Artigo em Inglês | MEDLINE | ID: mdl-36916924

4.

TRIM25 and ZAP target the Ebola virus ribonucleoprotein complex to mediate interferon-induced restriction.

Galão, Rui Pedro; Wilson, Harry; Schierhorn, Kristina L; Debeljak, Franka; Bodmer, Bianca S; Goldhill, Daniel; Hoenen, Thomas; Wilson, Sam J; Swanson, Chad M; Neil, Stuart J D.

PLoS Pathog ; 18(5): e1010530, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35533151

5.

Inhibition of human cytomegalovirus replication by interferon alpha can involve multiple anti-viral factors.

Chowdhury, Shabab; Latham, Katie A; Tran, Andy C; Carroll, Christopher J; Stanton, Richard J; Weekes, Michael P; Neil, Stuart J D; Swanson, Chad M; Strang, Blair L.

J Gen Virol ; 104(12)2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-38063292

6.

The P681H Mutation in the Spike Glycoprotein of the Alpha Variant of SARS-CoV-2 Escapes IFITM Restriction and Is Necessary for Type I Interferon Resistance.

Lista, Maria Jose; Winstone, Helena; Wilson, Harry D; Dyer, Adam; Pickering, Suzanne; Galao, Rui Pedro; De Lorenzo, Giuditta; Cowton, Vanessa M; Furnon, Wilhelm; Suarez, Nicolas; Orton, Richard; Palmarini, Massimo; Patel, Arvind H; Snell, Luke; Nebbia, Gaia; Swanson, Chad; Neil, Stuart J D.

J Virol ; 96(23): e0125022, 2022 12 14.

Artigo em Inglês | MEDLINE | ID: mdl-36350154

7.

S-farnesylation is essential for antiviral activity of the long ZAP isoform against RNA viruses with diverse replication strategies.

Kmiec, Dorota; Lista, María José; Ficarelli, Mattia; Swanson, Chad M; Neil, Stuart J D.

PLoS Pathog ; 17(10): e1009726, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34695163

8.

The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.

Rafii, Michael S; Sperling, Reisa A; Donohue, Michael C; Zhou, Jin; Roberts, Claire; Irizarry, Michael C; Dhadda, Shobha; Sethuraman, Gopalan; Kramer, Lynn D; Swanson, Chad J; Li, David; Krause, Stephen; Rissman, Robert A; Walter, Sarah; Raman, Rema; Johnson, Keith A; Aisen, Paul S.

Alzheimers Dement ; 19(4): 1227-1233, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-35971310

9.

The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2.

Winstone, Helena; Lista, Maria Jose; Reid, Alisha C; Bouton, Clement; Pickering, Suzanne; Galao, Rui Pedro; Kerridge, Claire; Doores, Katie J; Swanson, Chad M; Neil, Stuart J D.

J Virol ; 95(9)2021 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-33563656

10.

CpG Dinucleotides Inhibit HIV-1 Replication through Zinc Finger Antiviral Protein (ZAP)-Dependent and -Independent Mechanisms.

Ficarelli, Mattia; Antzin-Anduetza, Irati; Hugh-White, Rupert; Firth, Andrew E; Sertkaya, Helin; Wilson, Harry; Neil, Stuart J D; Schulz, Reiner; Swanson, Chad M.

J Virol ; 94(6)2020 02 28.

Artigo em Inglês | MEDLINE | ID: mdl-31748389

11.

HIV-1 and M-PMV RNA Nuclear Export Elements Program Viral Genomes for Distinct Cytoplasmic Trafficking Behaviors.

Pocock, Ginger M; Becker, Jordan T; Swanson, Chad M; Ahlquist, Paul; Sherer, Nathan M.

PLoS Pathog ; 12(4): e1005565, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-27070420

12.

SnapShot: HIV-1 proteins.

Swanson, Chad M; Malim, Michael H.

Cell ; 133(4): 742, 742.e1, 2008 May 16.

Artigo em Inglês | MEDLINE | ID: mdl-18485880

13.

Increasing the CpG dinucleotide abundance in the HIV-1 genomic RNA inhibits viral replication.

Antzin-Anduetza, Irati; Mahiet, Charlotte; Granger, Luke A; Odendall, Charlotte; Swanson, Chad M.

Retrovirology ; 14(1): 49, 2017 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-29121951

14.

Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.

Shankar-Hari, Manu; Fear, David; Lavender, Paul; Mare, Tracey; Beale, Richard; Swanson, Chad; Singer, Mervyn; Spencer, Jo.

Crit Care Med ; 45(5): 875-882, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28296810

15.

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

Apolonia, Luis; Schulz, Reiner; Curk, Tomaz; Rocha, Paula; Swanson, Chad M; Schaller, Torsten; Ule, Jernej; Malim, Michael H.

PLoS Pathog ; 11(1): e1004609, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25590131

16.

Regulation of human immunodeficiency virus type 1 (HIV-1) mRNA translation.

Hidalgo, Laura; Swanson, Chad M.

Biochem Soc Trans ; 45(2): 353-364, 2017 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-28408475

17.

Control of HIV-1 gene expression by SR proteins.

Mahiet, Charlotte; Swanson, Chad M.

Biochem Soc Trans ; 44(5): 1417-1425, 2016 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-27911724

18.

Utilising mass cytometry with CD45 barcoding and standardised leucocyte phenotyping for immune trajectory assessment in critically ill patients.

Fish, Matthew; Ellis, Richard; Bishop, Cynthia; Todd, Katrina; Petrov, Nedyalko; Singer, Mervyn; Swanson, Chad M; Shankar-Hari, Manu.

Br J Anaesth ; 126(4): e149-e152, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33549322

19.

Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropism.

Aligeti, Mounavya; Behrens, Ryan T; Pocock, Ginger M; Schindelin, Johannes; Dietz, Christian; Eliceiri, Kevin W; Swanson, Chad M; Malim, Michael H; Ahlquist, Paul; Sherer, Nathan M.

J Virol ; 88(24): 14207-21, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25275125

20.

Syn-CpG-Spacer: A Panel web app for synonymous recoding of viral genomes with CpG dinucleotides.

Sulkowski, Aleksander; Bouton, Clément; Swanson, Chad.

J Open Source Softw ; 9(96): 6332, 2024 Apr 03.

Artigo em Inglês | MEDLINE | ID: mdl-38650605

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