Detalhe da pesquisa
1.
Exploring the importance of zinc binding and steric/hydrophobic factors in novel HCV replication inhibitors.
Bioorg Med Chem Lett
; 26(4): 1196-9, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26804234
2.
UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication.
Bioorg Med Chem Lett
; 24(2): 609-12, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24360997
3.
Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes.
Nat Commun
; 14(1): 4798, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558718
4.
Allosteric Binders of ACE2 Are Promising Anti-SARS-CoV-2 Agents.
ACS Pharmacol Transl Sci
; 5(7): 468-478, 2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35821746
5.
Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents.
bioRxiv
; 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313579
6.
A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase.
Mol Biol Cell
; 33(13): ar120, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36074076
7.
Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo-ß-Lactamase NDM-1.
ChemMedChem
; 16(4): 654-661, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33211374
8.
Hybrid In Silico Approach Reveals Novel Inhibitors of Multiple SARS-CoV-2 Variants.
ACS Pharmacol Transl Sci
; 4(5): 1675-1688, 2021 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34608449
9.
Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.
J Med Chem
; 64(13): 9431-9443, 2021 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34184537
10.
Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites.
Sci Rep
; 11(1): 2121, 2021 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33483532
11.
Identification and Profiling of a Novel Diazaspiro[3.4]octane Chemical Series Active against Multiple Stages of the Human Malaria Parasite Plasmodium falciparum and Optimization Efforts.
J Med Chem
; 64(4): 2291-2309, 2021 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33573376
12.
Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1.
Cell Chem Biol
; 27(7): 780-792.e5, 2020 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32386595
13.
Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion.
Nat Microbiol
; 5(12): 1532-1541, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32868923
14.
Progress Towards Synthetic Chlorins with Graded Polarity, Conjugatable Substituents, and Wavelength Tunability.
J Porphyr Phthalocyanines
; 19(4): 547-572, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26640361