Detalhe da pesquisa
1.
PPARγ-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development.
Bioorg Med Chem
; 26(22): 5870-5884, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429097
2.
Insulin sensitizers in 2023: lessons learned and new avenues for investigation.
Expert Opin Investig Drugs
; 32(9): 803-811, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37755339
3.
A DUAL MTOR/NAD+ ACTING GEROTHERAPY.
bioRxiv
; 2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711589
4.
Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs.
Chem Phys Lipids
; 243: 105178, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35122738
5.
The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase.
Bioorg Med Chem Lett
; 20(6): 1994-2000, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167488
6.
Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK.
Bioorg Med Chem Lett
; 20(24): 7429-34, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21036042
7.
Property-Driven Design and Development of Lipids for Efficient Delivery of siRNA.
J Med Chem
; 63(21): 12992-13012, 2020 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33119286
8.
Furan-Terminated N-Acyliminium Ion Initiated Cyclizations in Alkaloid Synthesis.
J Org Chem
; 63(20): 6914-6928, 1998 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-11672313
9.
Insulin sensitizers in 2013: new insights for the development of novel therapeutic agents to treat metabolic diseases.
Expert Opin Investig Drugs
; 23(1): 1-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24073940
10.
Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1).
J Med Chem
; 54(24): 8490-500, 2011 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22040023
11.
Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors.
J Med Chem
; 54(9): 3393-417, 2011 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21446745
12.
Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.
J Med Chem
; 52(22): 7211-9, 2009 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19873974
13.
2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases.
Bioorg Med Chem Lett
; 17(12): 3349-53, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17434304