Detalhe da pesquisa
1.
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member.
Mol Biol Evol
; 40(2)2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36656997
2.
Mitochondrial Bioenergetics, Redox Balance, and Calcium Homeostasis Dysfunction with Defective Ultrastructure and Quality Control in the Hippocampus of Aged Female C57BL/6J Mice.
Int J Mol Sci
; 24(6)2023 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982549
3.
Age-Dependent Behavioral and Synaptic Dysfunction Impairment Are Improved with Long-Term Andrographolide Administration in Long-Lived Female Degus (Octodon degus).
Int J Mol Sci
; 24(2)2023 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674622
4.
WNT Signaling Is a Key Player in Alzheimer's Disease.
Handb Exp Pharmacol
; 269: 357-382, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486097
5.
Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20-APP transgenic and wild-type mice.
J Neurochem
; 144(4): 443-465, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29240990
6.
Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-ß (Aß)42 peptides.
J Neurochem
; 139(6): 1175-1191, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27778356
7.
Wnt signaling pathway improves central inhibitory synaptic transmission in a mouse model of Duchenne muscular dystrophy.
Neurobiol Dis
; 86: 109-20, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26626079
8.
Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3ß: autoregulation of GSK-3ß in vivo.
Biochem J
; 466(2): 415-30, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25423492
9.
Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease.
Proc Natl Acad Sci U S A
; 109(34): 13835-40, 2012 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22869717
10.
Andrographolide Stimulates Neurogenesis in the Adult Hippocampus.
Neural Plast
; 2015: 935403, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26798521
11.
GOLPH3 Participates in Mitochondrial Fission and Is Necessary to Sustain Bioenergetic Function in MDA-MB-231 Breast Cancer Cells.
Cells
; 13(4)2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38391929
12.
Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer's disease.
Front Aging Neurosci
; 15: 1250342, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37810621
13.
Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer's disease.
Neural Regen Res
; 17(8): 1645-1651, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017410
14.
Pathologically phosphorylated tau at S396/404 (PHF-1) is accumulated inside of hippocampal synaptic mitochondria of aged Wild-type mice.
Sci Rep
; 11(1): 4448, 2021 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33627790
15.
Synaptic Mitochondria: An Early Target of Amyloid-ß and Tau in Alzheimer's Disease.
J Alzheimers Dis
; 84(4): 1391-1414, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34719499
16.
Tau Deletion Prevents Cognitive Impairment and Mitochondrial Dysfunction Age Associated by a Mechanism Dependent on Cyclophilin-D.
Front Neurosci
; 14: 586710, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33679286
17.
Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degus.
Front Cell Dev Biol
; 8: 734, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32850846
18.
Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss.
Redox Biol
; 34: 101558, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32447261
19.
Stimulation of Melanocortin Receptor-4 (MC4R) Prevents Mitochondrial Damage Induced by Binge Ethanol Protocol in Adolescent Rat Hippocampus.
Neuroscience
; 438: 70-85, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32416118
20.
Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aß Aggregation.
Pharmaceuticals (Basel)
; 13(2)2020 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024240