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Br J Nutr ; 113(5): 813-21, 2015 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-25677713

RESUMO

Intakes of micronutrient-rich foods are low among Indian women of reproductive age. We investigated whether consumption of a food-based micronutrient-rich snack increased markers of blood micronutrient concentrations when compared with a control snack. Non-pregnant women (n 222) aged 14-35 years living in a Mumbai slum were randomised to receive a treatment snack (containing green leafy vegetables, dried fruit and whole milk powder), or a control snack containing foods of low micronutrient content such as wheat flour, potato and tapioca. The snacks were consumed under observation 6 d per week for 12 weeks, compliance was recorded, and blood was collected at 0 and 12 weeks. Food-frequency data were collected at both time points. Compliance (defined as the proportion of women who consumed ≥ 3 snacks/week) was >85 % in both groups. We assessed the effects of group allocation on 12-week nutrient concentrations using ANCOVA models with respective 0-week concentrations, BMI, compliance, standard of living, fruit and green leafy vegetable consumption and use of synthetic nutrients as covariates. The treatment snack significantly increased ß-carotene concentrations (treatment effect: 47·1 nmol/l, 95 % CI 6·5, 87·7). There was no effect of group allocation on concentrations of ferritin, retinol, ascorbate, folate or vitamin B12. The present study shows that locally sourced foods can be made into acceptable snacks that may increase serum ß-carotene concentrations among women of reproductive age. However, no increase in circulating concentrations of the other nutrients measured was observed.


Assuntos
Deficiências Nutricionais/dietoterapia , Frutas , Micronutrientes/deficiência , Proteínas do Leite/uso terapêutico , Folhas de Planta , Lanches , Verduras , Adolescente , Adulto , Biomarcadores/sangue , Deficiências Nutricionais/economia , Deficiências Nutricionais/etnologia , Deficiências Nutricionais/etiologia , Dieta/efeitos adversos , Dieta/economia , Dieta/etnologia , Terapia Diretamente Observada , Feminino , Alimentos em Conserva , Humanos , Índia , Micronutrientes/sangue , Micronutrientes/economia , Micronutrientes/uso terapêutico , Estado Nutricional/etnologia , Cooperação do Paciente/etnologia , Pobreza , Saúde da População Urbana/etnologia , Adulto Jovem , beta Caroteno/sangue , beta Caroteno/deficiência , beta Caroteno/economia , beta Caroteno/uso terapêutico
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