Detalhe da pesquisa
1.
Metabolite-Enzyme Coevolution: From Single Enzymes to Metabolic Pathways and Networks.
Annu Rev Biochem
; 87: 187-216, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925259
2.
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints.
Cell
; 164(3): 476-86, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26806127
3.
Automated Design of Efficient and Functionally Diverse Enzyme Repertoires.
Mol Cell
; 72(1): 178-186.e5, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30270109
4.
Enzyme promiscuity: a mechanistic and evolutionary perspective.
Annu Rev Biochem
; 79: 471-505, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20235827
5.
Utilization of diverse organophosphorus pollutants by marine bacteria.
Proc Natl Acad Sci U S A
; 119(32): e2203604119, 2022 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917352
6.
The evolutionary history of the HUP domain.
Crit Rev Biochem Mol Biol
; 57(1): 1-15, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34384295
7.
A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis.
Nat Chem Biol
; 18(2): 161-170, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931064
8.
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Mol Cell
; 63(2): 337-346, 2016 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27425410
9.
On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life.
Proc Natl Acad Sci U S A
; 118(21)2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001607
10.
Helicase-like functions in phosphate loop containing beta-alpha polypeptides.
Proc Natl Acad Sci U S A
; 118(16)2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846247
11.
On the Origins of Enzymes: Phosphate-Binding Polypeptides Mediate Phosphoryl Transfer to Synthesize Adenosine Triphosphate.
J Am Chem Soc
; 2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36951643
12.
Short and simple sequences favored the emergence of N-helix phospho-ligand binding sites in the first enzymes.
Proc Natl Acad Sci U S A
; 117(10): 5310-5318, 2020 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32079722
13.
Primordial emergence of a nucleic acid-binding protein via phase separation and statistical ornithine-to-arginine conversion.
Proc Natl Acad Sci U S A
; 117(27): 15731-15739, 2020 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32561643
14.
Peptide-RNA Coacervates as a Cradle for the Evolution of Folded Domains.
J Am Chem Soc
; 144(31): 14150-14160, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35904499
15.
Bridging Themes: Short Protein Segments Found in Different Architectures.
Mol Biol Evol
; 38(6): 2191-2208, 2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502503
16.
Local fitness landscape of the green fluorescent protein.
Nature
; 533(7603): 397-401, 2016 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27193686
17.
Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition.
Mol Biol Evol
; 37(4): 1133-1147, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31873734
18.
Quinone Methide-Based Organophosphate Hydrolases Inhibitors: Trans Proximity Labelers versus Cis Labeling Activity-Based Probes.
Chembiochem
; 22(5): 894-903, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105515
19.
Determining the interaction status and evolutionary fate of duplicated homomeric proteins.
PLoS Comput Biol
; 16(8): e1008145, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853212
20.
Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.
Mol Cell
; 70(2): 380, 2018 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29677494