Detalhe da pesquisa
1.
Effectiveness of a symptom-clinic intervention delivered by general practitioners with an extended role for people with multiple and persistent physical symptoms in England: the Multiple Symptoms Study 3 pragmatic, multicentre, parallel-group, individually randomised controlled trial.
Lancet
; 403(10444): 2619-2629, 2024 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38879261
2.
Glucocerebrosidase reduces the spread of protein aggregation in a Drosophila melanogaster model of neurodegeneration by regulating proteins trafficked by extracellular vesicles.
PLoS Genet
; 17(2): e1008859, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539341
3.
Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles.
PLoS Genet
; 14(9): e1007694, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30256786
4.
Glucocerebrosidase Deficiency in Drosophila Results in α-Synuclein-Independent Protein Aggregation and Neurodegeneration.
PLoS Genet
; 12(3): e1005944, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27019408
5.
PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix.
PLoS Genet
; 10(5): e1004279, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24874806
6.
The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo.
Proc Natl Acad Sci U S A
; 110(16): 6400-5, 2013 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23509287
7.
A Drosophila model for mechanistic investigation of tau protein spread.
bioRxiv
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712083
8.
Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation.
bioRxiv
; 2023 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168223
9.
Study protocol for the Multiple Symptoms Study 3: a pragmatic, randomised controlled trial of a clinic for patients with persistent (medically unexplained) physical symptoms.
BMJ Open
; 12(11): e066511, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36379663
10.
Surveillance mammography for detecting ipsilateral breast tumour recurrence and metachronous contralateral breast cancer: a systematic review.
Eur Radiol
; 21(12): 2484-91, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21833567
11.
The PINK1/Parkin pathway regulates mitochondrial morphology.
Proc Natl Acad Sci U S A
; 105(5): 1638-43, 2008 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18230723
12.
Slowed Protein Turnover in Aging Drosophila Reflects a Shift in Cellular Priorities.
J Gerontol A Biol Sci Med Sci
; 76(10): 1734-1739, 2021 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33453098
13.
Shockwave Lithotripsy Versus Ureteroscopic Treatment as Therapeutic Interventions for Stones of the Ureter (TISU): A Multicentre Randomised Controlled Non-inferiority Trial.
Eur Urol
; 80(1): 46-54, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33810921
14.
Autophagy accounts for approximately one-third of mitochondrial protein turnover and is protein selective.
Autophagy
; 15(9): 1592-1605, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865561
15.
Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration.
Cell Death Dis
; 9(3): 304, 2018 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467464
16.
Lon protease inactivation in Drosophila causes unfolded protein stress and inhibition of mitochondrial translation.
Cell Death Discov
; 4: 51, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30374414
17.
Effect of enhanced feedback and brief educational reminder messages on laboratory test requesting in primary care: a cluster randomised trial.
Lancet
; 367(9527): 1990-6, 2006 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16782489
18.
Changing physicians' behavior: what works and thoughts on getting more things to work.
J Contin Educ Health Prof
; 22(4): 237-43, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12613059
19.
VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations.
Neuron
; 78(1): 65-80, 2013 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23498974
20.
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway.
PLoS One
; 5(4): e10054, 2010 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20383334