Detalhe da pesquisa
1.
Genotoxicity assessment of peptide/protein-related biotherapeutics: points to consider before testing.
Mutagenesis
; 31(4): 375-84, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27000792
2.
Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities.
Regul Toxicol Pharmacol
; 67(1): 39-52, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23669331
3.
Compilation and use of genetic toxicity historical control data.
Mutat Res
; 723(2): 87-90, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20933606
4.
Strategies in case of positive in vivo results in genotoxicity testing.
Mutat Res
; 723(2): 121-8, 2011 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20854927
5.
Utility of a next-generation framework for assessment of genomic damage: A case study using the pharmaceutical drug candidate etoposide.
Environ Mol Mutagen
; 62(9): 512-525, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34775645
6.
Permitted daily exposure limits for noteworthy N-nitrosamines.
Environ Mol Mutagen
; 62(5): 293-305, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34089278
7.
Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test.
Mutat Res
; 702(2): 148-56, 2010 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20398790
8.
Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Mutat Res
; 702(1): 40-69, 2010 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20656055
9.
Application of the adverse outcome pathway framework to genotoxic modes of action.
Environ Mol Mutagen
; 61(1): 114-134, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31603995
10.
High information content assays for genetic toxicology testing: A report of the International Workshops on Genotoxicity Testing (IWGT).
Mutat Res Genet Toxicol Environ Mutagen
; 847: 403022, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31699343
11.
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
Mutat Res Genet Toxicol Environ Mutagen
; 839: 21-35, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744809
12.
Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells.
Mutat Res Genet Toxicol Environ Mutagen
; 825: 40-50, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29307374
13.
Application of toxicogenomics to genetic toxicology risk assessment.
Environ Mol Mutagen
; 48(5): 369-79, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17567850
14.
Characterization of DNA reactive and non-DNA reactive anticancer drugs by gene expression profiling.
Mutat Res
; 619(1-2): 16-29, 2007 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17374387
15.
Relevance and follow-up of positive results in in vitro genetic toxicity assays: an ILSI-HESI initiative.
Mutat Res
; 633(2): 67-79, 2007 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-17616430
16.
Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.
Mutat Res
; 627(1): 31-5, 2007 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17118697
17.
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Mutat Res
; 628(1): 31-55, 2007 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17293159
18.
Main issues addressed in the 2014-2015 revisions to the OECD Genetic Toxicology Test Guidelines.
Environ Mol Mutagen
; 58(5): 284-295, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28266061
19.
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.
Environ Mol Mutagen
; 58(3): 146-161, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28370322
20.
Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.
Environ Mol Mutagen
; 58(5): 264-283, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27650663