Pesquisa | BVS Integralidade em Saúde

1.

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.

Padmanabhan, Srivatsan; Mukhopadhyay, Arnab; Narasimhan, Sri Devi; Tesz, Gregory; Czech, Michael P; Tissenbaum, Heidi A.

Cell ; 136(5): 939-51, 2009 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-19249087

2.

RTEL1 maintains genomic stability by suppressing homologous recombination.

Barber, Louise J; Youds, Jillian L; Ward, Jordan D; McIlwraith, Michael J; O'Neil, Nigel J; Petalcorin, Mark I R; Martin, Julie S; Collis, Spencer J; Cantor, Sharon B; Auclair, Melissa; Tissenbaum, Heidi; West, Stephen C; Rose, Ann M; Boulton, Simon J.

Cell ; 135(2): 261-71, 2008 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-18957201

3.

Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans.

Seo, Yonghak; Kingsley, Samuel; Walker, Griffin; Mondoux, Michelle A; Tissenbaum, Heidi A.

Proc Natl Acad Sci U S A ; 115(12): E2791-E2800, 2018 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-29511104

4.

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Bansal, Ankita; Zhu, Lihua J; Yen, Kelvin; Tissenbaum, Heidi A.

Proc Natl Acad Sci U S A ; 112(3): E277-86, 2015 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-25561524

5.

Complex expression dynamics and robustness in C. elegans insulin networks.

Ritter, Ashlyn D; Shen, Yuan; Fuxman Bass, Juan; Jeyaraj, Sankarganesh; Deplancke, Bart; Mukhopadhyay, Arnab; Xu, Jian; Driscoll, Monica; Tissenbaum, Heidi A; Walhout, Albertha J M.

Genome Res ; 23(6): 954-65, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23539137

6.

A new DAF-16 isoform regulates longevity.

Kwon, Eun-Soo; Narasimhan, Sri Devi; Yen, Kelvin; Tissenbaum, Heidi A.

Nature ; 466(7305): 498-502, 2010 Jul 22.

Artigo em Inglês | MEDLINE | ID: mdl-20613724

7.

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation.

Oh, Seung Wook; Mukhopadhyay, Arnab; Dixit, Bharat L; Raha, Tamal; Green, Michael R; Tissenbaum, Heidi A.

Nat Genet ; 38(2): 251-7, 2006 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-16380712

8.

Using C. elegans for aging research.

Tissenbaum, Heidi A.

Invertebr Reprod Dev ; 59(sup1): 59-63, 2015 Jan 30.

Artigo em Inglês | MEDLINE | ID: mdl-26136622

9.

PDP-1 links the TGF-ß and IIS pathways to regulate longevity, development, and metabolism.

Narasimhan, Sri Devi; Yen, Kelvin; Bansal, Ankita; Kwon, Eun-Soo; Padmanabhan, Srivatsan; Tissenbaum, Heidi A.

PLoS Genet ; 7(4): e1001377, 2011 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-21533078

10.

Imaging lipid metabolism in live Caenorhabditis elegans using fingerprint vibrations.

Wang, Ping; Liu, Bin; Zhang, Delong; Belew, Micah Y; Tissenbaum, Heidi A; Cheng, Ji-Xin.

Angew Chem Int Ed Engl ; 53(44): 11787-92, 2014 Oct 27.

Artigo em Inglês | MEDLINE | ID: mdl-25195517

11.

SIRT1, resveratrol and aging.

Rogina, Blanka; Tissenbaum, Heidi A.

Front Genet ; 15: 1393181, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38784035

12.

Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens.

Kingsley, Samuel F; Seo, Yonghak; Wood, Alicia; Wani, Khursheed A; Gonzalez, Xavier; Irazoqui, Javier; Finkel, Steven E; Tissenbaum, Heidi A.

Sci Rep ; 14(1): 13177, 2024 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-38849503

13.

Integration of ß-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Parker, J Alex; Vazquez-Manrique, Rafael P; Tourette, Cendrine; Farina, Francesca; Offner, Nicolas; Mukhopadhyay, Arnab; Orfila, Anne-Marie; Darbois, Aurélie; Menet, Sophie; Tissenbaum, Heidi A; Neri, Christian.

J Neurosci ; 32(36): 12630-40, 2012 Sep 05.

Artigo em Inglês | MEDLINE | ID: mdl-22956852

14.

Serotonin's SOS signal.

Tissenbaum, Heidi A.

Cell Metab ; 4(6): 415-7, 2006 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17141622

15.

Bacterial processing of glucose modulates C. elegans lifespan and healthspan.

Kingsley, Samuel F; Seo, Yonghak; Allen, Calista; Ghanta, Krishna S; Finkel, Steven; Tissenbaum, Heidi A.

Sci Rep ; 11(1): 5931, 2021 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-33723307

16.

C. elegans tubby regulates life span and fat storage by two independent mechanisms.

Mukhopadhyay, Arnab; Deplancke, Bart; Walhout, Albertha J M; Tissenbaum, Heidi A.

Cell Metab ; 2(1): 35-42, 2005 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-16054097

17.

Model organisms as a guide to mammalian aging.

Tissenbaum, Heidi A; Guarente, Leonard.

Dev Cell ; 2(1): 9-19, 2002 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-11782310

18.

DAF-16: FOXO in the Context of C. elegans.

Tissenbaum, Heidi A.

Curr Top Dev Biol ; 127: 1-21, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29433733

19.

Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

Wang, Yamei; Tissenbaum, Heidi A.

Mech Ageing Dev ; 127(1): 48-56, 2006 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-16280150

20.

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

Wang, Yamei; Oh, Seung Wook; Deplancke, Bart; Luo, Jianyuan; Walhout, Albertha J M; Tissenbaum, Heidi A.

Mech Ageing Dev ; 127(9): 741-7, 2006 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16860373

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A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.

RTEL1 maintains genomic stability by suppressing homologous recombination.

Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans.

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Complex expression dynamics and robustness in C. elegans insulin networks.

A new DAF-16 isoform regulates longevity.

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation.

Using C. elegans for aging research.

PDP-1 links the TGF-ß and IIS pathways to regulate longevity, development, and metabolism.

Imaging lipid metabolism in live Caenorhabditis elegans using fingerprint vibrations.

SIRT1, resveratrol and aging.

Glucose-fed microbiota alters C. elegans intestinal epithelium and increases susceptibility to multiple bacterial pathogens.

Integration of ß-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Serotonin's SOS signal.

Bacterial processing of glucose modulates C. elegans lifespan and healthspan.

C. elegans tubby regulates life span and fat storage by two independent mechanisms.

Model organisms as a guide to mammalian aging.

DAF-16: FOXO in the Context of C. elegans.

Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.