RESUMO
Yew leaves poisoning is a rare life-threatening intoxication, whose diagnosis can be difficult. Initial symptoms are nausea, vomiting, abdominal pain, dizziness, tachycardia, muscle weakness, confusion, beginning within 1 hr from ingestion and followed by bradycardia, ventricular arrhythmias, ventricular fibrillation, severe hypotension, and death. Taxine-derived alkaloids are responsible for the toxicity of the yew leaves, blocking sodium and calcium channels, and causing conduction abnormalities. Because of lack of a specific antidote and limited efficacy of common antiarrhythmic drugs, prompt diagnosis, detoxification measures, and immediate hemodynamic support (also with transvenous cardiac stimulation) are essential.
Assuntos
Arritmias Cardíacas/induzido quimicamente , Cephalotaxus/intoxicação , Eletrocardiografia/métodos , Parada Cardíaca/induzido quimicamente , Extratos Vegetais/intoxicação , Folhas de Planta/intoxicação , Agonistas alfa-Adrenérgicos/uso terapêutico , Adulto , Idoso , Amiodarona/uso terapêutico , Antiarrítmicos/uso terapêutico , Arritmias Cardíacas/terapia , Reanimação Cardiopulmonar , Carvão Vegetal/uso terapêutico , Feminino , Lavagem Gástrica , Parada Cardíaca/terapia , Humanos , Sulfato de Magnésio/uso terapêutico , Masculino , Pessoa de Meia-Idade , Norepinefrina/uso terapêutico , Marca-Passo Artificial , Bicarbonato de Sódio/uso terapêutico , Resultado do TratamentoRESUMO
On Sept. 19th, 2021, the largest historical eruption on the island of La Palma began, which had a significant scientific, social, and economic impact. The 2021 Tajogaite eruption was characterised by short precursors, lasting only 8 days. The seismicity started on Sept. 11th with a westward and upward migration of hypocenters. Permanent GNSS stations started recording deformation on Sept. 12th on the island's western side, which reached more than 15 cm just before the eruption. After the eruption onset, the ground deformation increased, reaching a maximum on Sept. 22nd and showing a nearly steady deflation trend in the following months. To better understand the dynamics of the eruption, we exploited a joint dataset of GNSS and Sentinel-1 SBAS time series along both ascending and descending orbits. To obtain the geometry of the causative source of the ground deformation, we combined the result of a preliminary non-linear inversion and the precise location of the seismicity. The resulting geometry of the source is that of a twisted dike bending eastward. We performed inverse modelling to obtain the spatiotemporal kinematics of the opening function of the dike. The forward modelling has been realised using a 3D finite-element approach considering the island's topography. Our findings reveal a close correspondence between the magmatic intrusion and pre-eruptive seismicity. The ascent of the magma occurred along two branches, and the rheology of a previously identified ductile layer strongly affected the magma propagation process. Finally, we found evidence of an early shallow deformation, which we interpret as the effect of ascending hydrothermal fluids. Our findings highlight the need for advanced modelling to understand pre-eruptive processes in basaltic volcanoes.
RESUMO
The contrasting dynamics between Mauna Loa and Kilauea have been studied over the last 100 years from multiple viewpoints. The fact that dynamic changes of one volcano trigger a dynamic response of the other volcano indicates a connection may exist. Petrological works show a direct relationship between the magmatic systems of these two volcanoes is not possible. We analysed DInSAR data and GPS measurements of ground deformation patterns associated with the activity of Mauna Loa and Kilauea volcanoes. The DInSAR SBAS dataset spans the interval between 2003 and 2010, and was acquired along ascending and descending orbits of the ENVISAT (ESA) satellite under different look angles. Of the 10 tracks that cover the Big Island (Hawai'i), 4 cover both volcanic edifices. Using GPS measurements, we computed the areal strain on 15 triplets of stations for Kilauea volcano and 11 for Mauna Loa volcano. DInSAR data was analysed by applying Independent Component Analysis (ICA) to decompose the time-varying ground deformation pattern of both volcanoes. The results revealed anticorrelated ground deformation behaviour of the main calderas of Mauna Loa and Kilauea, meaning that the opposite response is seen in the ground deformation of one volcano with respect to the other. At the same time, Kilauea exhibits a more complex pattern, with an additional component, which appears not to be correlated with the dynamics of Mauna Loa. The GPS areal strain time series support these findings. To corroborate and help interpret the results, we performed inverse modelling of the observed ground deformation pattern using analytical source models. The results indicate that the ground deformation of Mauna Loa is associated with a dike-shaped source located at 6.2 km depth. In comparison, the anticorrelated ground deformation of Kilauea is associated with a volumetric source at 1.2 km depth. This excludes a hydraulic connection as a possible mechanism to explain the anticorrelated behaviour; instead, we postulate a stress-transfer mechanism. To support this hypothesis, we performed a 3D numerical modelling of stress and strain fields in the study area, determining the elastic interaction of each source over the others. The most relevant finding is that the Mauna Loa shallow plumbing system can affect the shallowest magmatic reservoir of Kilauea, while the opposite scenario is unlikely. Conversely, the second independent component observed at Kilauea is associated to a sill-shaped source located at a depth of 3.5 km, which is less affected by this interaction process.
RESUMO
We analyse the Mw 6.5, 2016 Amatrice-Norcia (Central Italy) seismic sequence by means of InSAR, GPS, seismological and geologic data. The >1000 km2 area affected by deformation is involving a volume of about 6000 km3 and the relocated seismicity is widely distributed in the hangingwall of the master fault system and the conjugate antithetic faults. Noteworthy, the coseismically subsided hangingwall volume is about 0.12 km3, whereas the uplifted adjacent volumes uplifted only 0.016 km3. Therefore, the subsided volume was about 7.5 times larger than the uplifted one. The coseismic motion requires equivalent volume at depth absorbing the hangingwall downward movement. This unbalance regularly occurs in normal fault-related earthquakes and can be inferred as a significant contribution to coseismic strain accomodated by a stress-drop driven collapse of precursory dilatancy. The vertical coseismic displacement is in fact larger than the horizontal component, consistent with the vertical orientation of the maximum lithostatic stress tensor.
RESUMO
AIMS: Although acute decompensated heart failure (ADHF) is a common cause of dyspnoea, its diagnosis still represents a challenge. Lung ultrasound (LUS) is an emerging point-of-care diagnostic tool, but its diagnostic performance for ADHF has not been evaluated in randomized studies. We evaluated, in patients with acute dyspnoea, accuracy and clinical usefulness of combining LUS with clinical assessment compared to the use of chest radiography (CXR) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) in conjunction with clinical evaluation. METHODS AND RESULTS: This was a randomized trial conducted in two emergency departments. After initial clinical evaluation, patients with acute dyspnoea were classified by the treating physician according to presumptive aetiology (ADHF or non-ADHF). Patients were subsequently randomized to continue with either LUS or CXR/NT-proBNP. A new diagnosis, integrating the results of both initial assessment and the newly obtained findings, was then recorded. Diagnostic accuracy and clinical usefulness of LUS and CXR/NT-proBNP approaches were calculated. A total of 518 patients were randomized. Addition of LUS had higher accuracy [area under the receiver operating characteristic curve (AUC) 0.95] than clinical evaluation alone (AUC 0.88) in identifying ADHF (P < 0.01). In contrast, use of CXR/NT-proBNP did not significantly increase the accuracy of clinical evaluation alone (AUC 0.87 and 0.85, respectively; P > 0.05). The diagnostic accuracy of the LUS-integrated approach was higher then that of the CXR/Nt-proBNP-integrated approach (AUC 0.95 vs. 0.87, p < 0.01). Combining LUS with the clinical evaluation reduced diagnostic errors by 7.98 cases/100 patients, as compared to 2.42 cases/100 patients in the CXR/Nt-proBNP group. CONCLUSION: Integration of LUS with clinical assessment for the diagnosis of ADHF in the emergency department seems to be more accurate than the current diagnostic approach based on CXR and NT-proBNP.
Assuntos
Dispneia/etiologia , Serviço Hospitalar de Emergência , Insuficiência Cardíaca/diagnóstico , Pulmão/diagnóstico por imagem , Ultrassonografia/métodos , Doença Aguda , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Dispneia/sangue , Dispneia/diagnóstico , Feminino , Insuficiência Cardíaca/complicações , Humanos , Masculino , Peptídeo Natriurético Encefálico/sangue , Fragmentos de Peptídeos/sangue , Valor Preditivo dos Testes , Curva ROC , Radiografia Torácica/métodosRESUMO
In actively deforming regions, crustal deformation is accommodated by earthquakes and through a variety of transient aseismic phenomena. Here, we study the 2010-2014 Pollino (Southern Italy) swarm sequence (main shock M W 5.1) located within the Pollino seismic gap, by analysing the surface deformation derived from Global Positioning System and Synthetic Aperture Radar data. Inversions of geodetic time series show that a transient slip, with the same mechanism of the main shock, started about 3-4 months before the main shock and lasted almost one year, evolving through time with acceleration phases that correlate with the rate of seismicity. The moment released by the transient slip is equivalent to M W 5.5, significantly larger than the seismic moment release revealing therefore that a significant fraction of the overall deformation is released aseismically. Our findings suggest that crustal deformation in the Pollino gap is accommodated by infrequent "large" earthquakes (M W ≥ 6.5) and by aseismic episodes releasing a significant fraction of the accrued strain. Lower strain rates, relative to the adjacent Southern Apennines, and a mixed seismic/aseismic strain release are in favour of a longer recurrence for large magnitude earthquakes in the Pollino gap.
RESUMO
We found the first evidence, in the last 30 years, of a renewed magmatic activity at Campi Flegrei caldera from January 2012 to June 2013. The ground deformation, observed through satellite interferometry and GPS measurements, have been interpreted as the effect of the intrusion at shallow depth (3090 ± 138 m) of 0.0042 ± 0.0002 km(3) of magma within a sill. This interrupts about 28 years of dominant hydrothermal activity and occurs in the context of an unrest phase which began in 2005 and within a more general ground uplift that goes on since 1950. This discovery has implications on the evaluation of the volcanic risk and in the volcanic surveillance of this densely populated area.