Detalhe da pesquisa
1.
Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Cell
; 167(1): 171-186.e15, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27641501
2.
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Cell
; 150(3): 575-89, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863010
3.
Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 561(7723): 420, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046103
4.
Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.
Nature
; 510(7506): 547-51, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24870244
5.
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics.
Nat Chem Biol
; 12(2): 102-8, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26656089
6.
Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 475(7355): 231-4, 2011 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21753854
7.
Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.
Nature
; 526(7574): 596, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375002
8.
Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing.
Mol Cell
; 32(6): 838-48, 2008 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19111663
9.
Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.
PLoS Genet
; 9(5): e1003487, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23696745
10.
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Nat Chem Biol
; 9(12): 840-848, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161946
11.
Analysis of the activities of RAD54, a SWI2/SNF2 protein, using a specific small-molecule inhibitor.
J Biol Chem
; 288(44): 31567-80, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24043618
12.
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress.
Proc Natl Acad Sci U S A
; 108(21): 8773-8, 2011 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21555567
13.
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.
J Comput Aided Mol Des
; 27(5): 455-68, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23585218
14.
Identifying the proteins to which small-molecule probes and drugs bind in cells.
Proc Natl Acad Sci U S A
; 106(12): 4617-22, 2009 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19255428
15.
ChemBank: a small-molecule screening and cheminformatics resource database.
Nucleic Acids Res
; 36(Database issue): D351-9, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17947324
16.
Introduction: cell-based assays for high-throughput screening.
Methods Mol Biol
; 486: 1-12, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19347612
17.
Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.
Cancer Res
; 66(18): 8935-42, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16982730
18.
Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis.
Curr Biol
; 12(21): 1864-70, 2002 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12419188
19.
Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II.
Mol Biol Cell
; 14(2): 798-809, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12589071
20.
Characterization of the minimum domain required for targeting budding yeast myosin II to the site of cell division.
BMC Biol
; 4: 19, 2006 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16800887