Detalhe da pesquisa
1.
Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase.
Hum Mol Genet
; 30(8): 706-715, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33772540
2.
Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
Mol Psychiatry
; 26(9): 5441-5463, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514103
3.
N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation.
Proc Natl Acad Sci U S A
; 115(30): E7081-E7090, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29987005
4.
High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry.
J Biol Chem
; 294(6): 1915-1923, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30538129
5.
Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.
Hum Mol Genet
; 26(2): 395-406, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28017939
6.
Atraumatic versus conventional lumbar puncture needles: a systematic review and meta-analysis.
Lancet
; 391(10126): 1197-1204, 2018 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29223694
7.
Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization.
Hum Mol Genet
; 25(18): 3937-3945, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466181
8.
DNA repair: A unifying mechanism in neurodegeneration.
Nature
; 541(7635): 34-35, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002410
9.
A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease.
Hum Mol Genet
; 24(2): 450-62, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25205111
10.
Correction: Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology.
Mol Psychiatry
; 26(9): 5464, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32709993
11.
Live cell imaging and biophotonic methods reveal two types of mutant huntingtin inclusions.
Hum Mol Genet
; 23(9): 2324-38, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24334607
12.
Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.
Proc Natl Acad Sci U S A
; 110(36): 14610-5, 2013 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23898200
13.
Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice.
Proc Natl Acad Sci U S A
; 109(9): 3528-33, 2012 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331905
14.
Cofilin nuclear-cytoplasmic shuttling affects cofilin-actin rod formation during stress.
J Cell Sci
; 125(Pt 17): 3977-88, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22623727
15.
Identification of a karyopherin ß1/ß2 proline-tyrosine nuclear localization signal in huntingtin protein.
J Biol Chem
; 287(47): 39626-33, 2012 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23012356
16.
Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease.
Hum Mol Genet
; 20(10): 1937-51, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21355047
17.
Kinase inhibitors modulate huntingtin cell localization and toxicity.
Nat Chem Biol
; 7(7): 453-60, 2011 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-21623356
18.
PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.
Res Sq
; 2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945419
19.
PAM-flexible genome editing with an engineered chimeric Cas9.
Nat Commun
; 14(1): 6175, 2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37794046
20.
The impact of the COVID-19 pandemic on perceived publication pressure among academic researchers in Canada.
PLoS One
; 17(6): e0269743, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35731739