Detalhe da pesquisa
1.
Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3.
J Hepatol
; 74(6): 1416-1428, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340584
2.
Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer.
Am J Physiol Gastrointest Liver Physiol
; 318(1): G174-G188, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31630534
3.
A novel non-bile acid FXR agonist EDP-305 potently suppresses liver injury and fibrosis without worsening of ductular reaction.
Liver Int
; 40(7): 1655-1669, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32329946
4.
Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis.
Purinergic Signal
; 14(1): 37-46, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29134411
5.
Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal.
Gut
; 66(9): 1697-1708, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28073888
6.
Integrin αvß6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis.
Hepatology
; 63(1): 217-32, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26448099
7.
Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis.
Nat Commun
; 11(1): 2362, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32398673
8.
The ectonucleotidase ENTPD1/CD39 limits biliary injury and fibrosis in mouse models of sclerosing cholangitis.
Hepatol Commun
; 1(9): 957-972, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29404503