Factors contributing to late stillbirth among women with pregnancy hypertension in a developing country.

OBJECTIVE: To investigate the factors associated with late stillbirth among women with hypertensive disorders of pregnancy (HDP). MATERIAL AND METHODS: The clinical details of women with HDP having late stillbirth were compared with controls having livebirth. RESULTS: Total 208 cases and 288 controls were included in the study. Inadequate antenatal visits (p < 0.001, OR-5.92). birth weight < 2000 gms (p < 0.001, OR 10.3) and BW/PW ratio > 8 contributed significantly (p = 0.0001, OR-5.6) to stillbirth. CONCLUSION: Poor antenatal care, birth weight below 2000gms and high BW/PW ratio was associated with a higher risk of stillbirth.

First-trimester reference centiles of fetal biometry in Indian population.

AIM AND OBJECTIVE: To create crown-rump length (CRL)-based biometric chart for fetus in the first trimester among the Indian population. MATERIAL AND METHODS: Cross-sectional data were obtained from 400 singleton pregnancies between 11 and 14 weeks gestation with a normal outcome. Linear regression models were constructed; the mean and SD were derived as a function of CRL. RESULTS: There was a positive correlation of CRL with nuchal translucency (NT) (y = 0.0102x + 0.6307 R2 = 0.1177), biparietal diameter (BPD) (BPD = 0.032*CRL +0.185 R2 = 0.765), occipito-frontal diameter (OFD), lateral ventricular diameter (LV), abdominal circumference (AC) (AC = 0.944*CRL +9.684 R2 = 0.668), femur length (FL) (FL = 0.222*CRL -4.734 R2 = 0.661), fetal weight (FW) (FW = 1.328*CRL -10.41 R2 = 0.662). The regression models and centile charts of NT, BPD, OFD, LV, AC, and FW were constructed. Taking FW as the independent variable, a linear equation of BPD, AC, and FL to calculate weight was constructed. CONCLUSIONS: The first-trimester centile charts of fetal parameters can be used as a reference for Indian population in the determination of gestational age or other adverse outcomes.