Detalhe da pesquisa
1.
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Nucleic Acids Res
; 48(21): 12234-12251, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33211885
2.
mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome.
Int J Mol Sci
; 18(3)2017 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28241484
3.
A novel mouse model for the hyper-IgM syndrome: a spontaneous activation-induced cytidine deaminase mutation leading to complete loss of Ig class switching and reduced somatic hypermutation.
J Immunol
; 193(9): 4732-8, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25252954
4.
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.
Nucleic Acids Res
; 42(14): 9108-20, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25074383
5.
Quality assessment of LNP-RNA therapeutics with orthogonal analytical techniques.
J Control Release
; 367: 385-401, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38253203
6.
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.
Nucleic Acids Res
; 39(19): 8430-44, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21745813
7.
Systematic review: predictive value of organoids in colorectal cancer.
Sci Rep
; 13(1): 18124, 2023 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872318
8.
Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1.
ChemMedChem
; 18(1): e202200310, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36128847
9.
Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.
J Biol Chem
; 286(19): 16669-80, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454529
10.
Interlaboratory evaluation of a digital holographic microscopy-based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers.
Drug Deliv Transl Res
; 12(9): 2207-2224, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35799027
11.
A Children's Health Perspective on Nano- and Microplastics.
Environ Health Perspect
; 130(1): 15001, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080434
12.
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function.
Science
; 376(6600): 1471-1476, 2022 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35737787
13.
Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects.
Sci Rep
; 11(1): 3490, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568707
14.
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Cancer Res
; 81(22): 5733-5744, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34593524
15.
Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses.
Viruses
; 12(12)2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33322045
16.
Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.
Cancer Res
; 80(7): 1538-1550, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32019870
17.
The rate of base excision repair of uracil is controlled by the initiating glycosylase.
DNA Repair (Amst)
; 7(11): 1869-81, 2008 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18721906
18.
Computational and Experimental Druggability Assessment of Human DNA Glycosylases.
ACS Omega
; 4(7): 11642-11656, 2019 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31460271
19.
Targeting BER enzymes in cancer therapy.
DNA Repair (Amst)
; 71: 118-126, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228084
20.
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation.
Science
; 362(6416): 834-839, 2018 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30442810