Detalhe da pesquisa
1.
Increasing O-GlcNAcylation Attenuates tau Hyperphosphorylation and Behavioral Impairment in rTg4510 Tauopathy Mice.
J Integr Neurosci
; 22(5): 135, 2023 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37735138
2.
Dual strategy for reduced signal-suppression effects in matrix-assisted laser desorption/ionization mass spectrometry imaging.
Rapid Commun Mass Spectrom
; 33(22): 1711-1721, 2019 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31307118
3.
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
EMBO J
; 31(14): 3157-68, 2012 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22728825
4.
The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function.
Bioorg Med Chem Lett
; 24(22): 5195-8, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25442311
5.
Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model.
J Alzheimers Dis
; 93(1): 247-262, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37005884
6.
Highly Specific and Sensitive Target Binding by the Humanized pS396-Tau Antibody hC10.2 Across a Wide Spectrum of Alzheimer's Disease and Primary Tauopathy Postmortem Brains.
J Alzheimers Dis
; 88(1): 207-228, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570492
7.
Mitochondrial translocation of cofilin is an early step in apoptosis induction.
Nat Cell Biol
; 5(12): 1083-9, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14634665
8.
PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation.
Brain Pathol
; 31(1): 103-119, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32716602
9.
Anti-Aß Antibody Aducanumab Regulates the Proteome of Senile Plaques and Closely Surrounding Tissue in a Transgenic Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 79(1): 249-265, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33252074
10.
Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.
J Neurosci
; 29(33): 10405-9, 2009 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-19692615
11.
Proteomic and Unbiased Post-Translational Modification Profiling of Amyloid Plaques and Surrounding Tissue in a Transgenic Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 73(1): 393-411, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771055
12.
Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.
J Neurochem
; 110(5): 1377-87, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19519664
13.
Measurement of cellular beta-site of APP cleaving enzyme 1 activity and its modulation in neuronal assay systems.
Anal Biochem
; 387(2): 208-20, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19454261
14.
Tau Antibody Structure Reveals a Molecular Switch Defining a Pathological Conformation of the Tau Protein.
Sci Rep
; 8(1): 6209, 2018 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29670132
15.
Highly specific and selective anti-pS396-tau antibody C10.2 targets seeding-competent tau.
Alzheimers Dement (N Y)
; 4: 521-534, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30386817
16.
Wide spectrum modulation by KP-544 in models relevant for neuronal survival.
Neuroreport
; 18(6): 571-5, 2007 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17413659
17.
Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation.
Neuroreport
; 18(6): 559-63, 2007 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17413657
18.
Early depletion of CA1 neurons and late neurodegeneration in a mouse tauopathy model.
Brain Res
; 1665: 22-35, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28411086
19.
Hyperactivity with Agitative-Like Behavior in a Mouse Tauopathy Model.
J Alzheimers Dis
; 49(3): 783-95, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26519432
20.
Pharmacological inhibition of BACE1 impairs synaptic plasticity and cognitive functions.
Biol Psychiatry
; 77(8): 729-39, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25599931