Detalhe da pesquisa
1.
Systematic identification of structure-specific protein-protein interactions.
Mol Syst Biol
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38702390
2.
Tau depletion in human neurons mitigates Aß-driven toxicity.
Mol Psychiatry
; 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38361127
3.
Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Hum Mol Genet
; 28(12): 2001-2013, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753527
4.
RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes.
Neurobiol Dis
; 129: 56-66, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085228
5.
An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2.
Neurobiol Dis
; 127: 512-526, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30954703
6.
Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.
Hum Mol Genet
; 26(3): 552-566, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096185
7.
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.
Hum Mol Genet
; 25(5): 989-1000, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740550
8.
A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells.
Cerebellum
; 17(4): 419-427, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397531
9.
Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.
Nucleic Acids Res
; 44(22): 10960-10973, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27536002
10.
Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.
Anal Chem
; 89(4): 2440-2448, 2017 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28192931
11.
C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Stem Cells
; 34(8): 2063-78, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097283
12.
Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson's iPSC-dopamine neurons.
iScience
; 26(7): 107044, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37426342
13.
Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson's disease GBA-N370S dopamine neurons.
Cell Rep
; 42(3): 112180, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870058
14.
Cellular reprogramming: a new approach to modelling Parkinson's disease.
Biochem Soc Trans
; 40(5): 1152-7, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988881
15.
Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia.
Front Immunol
; 13: 1035532, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36439115
16.
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.
Sci Transl Med
; 13(594)2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011628
17.
ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism.
FEBS Lett
; 594(10): 1631-1644, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32232843
18.
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Stem Cell Reports
; 14(5): 892-908, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330447
19.
LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages.
Stem Cell Reports
; 14(5): 940-955, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32359446
20.
Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.
Cell Stem Cell
; 24(1): 93-106.e6, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30503143