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1.
Psychol Sci ; 34(1): 22-34, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36282991

RESUMO

History-graded increases in older adults' levels of cognitive performance are well documented, but little is known about historical shifts in within-person change: cognitive decline and onset of decline. We combined harmonized perceptual-motor speed data from independent samples recruited in 1990 and 2010 to obtain 2,008 age-matched longitudinal observations (M = 78 years, 50% women) from 228 participants in the Berlin Aging Study (BASE) and 583 participants in the Berlin Aging Study II (BASE-II). We used nonlinear growth models that orthogonalized within- and between-person age effects and controlled for retest effects. At age 78, the later-born BASE-II cohort substantially outperformed the earlier-born BASE cohort (d = 1.20; 25 years of age difference). Age trajectories, however, were parallel, and there was no evidence of cohort differences in the amount or rate of decline and the onset of decline. Cognitive functioning has shifted to higher levels, but cognitive decline in old age appears to proceed similarly as it did two decades ago.


Assuntos
Envelhecimento , Cognição , Humanos , Feminino , Idoso , Masculino , Envelhecimento/psicologia , Estudos Longitudinais
2.
Gerontology ; 68(2): 214-223, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34000719

RESUMO

INTRODUCTION: Control beliefs can protect against age-related declines in functioning. It is unclear whether neighborhood characteristics shape how much control people perceive over their life. This article studies associations of neighborhood characteristics with control beliefs of residents of a diverse metropolitan area (Berlin, Germany). METHODS: We combine self-report data about perceptions of control obtained from participants in the Berlin Aging Study II (N = 507, 60-87 years, 51% women) with multisource geo-referenced indicators of neighborhood characteristics using linear regression models. RESULTS: Findings indicate that objective neighborhood characteristics (i.e., unemployment rate) are indeed tied to perceptions of control, in particular, how much control participants feel others have over their lives. Including neighborhood characteristics in part doubled the amount of explained variance compared with a reference model covarying for demographic characteristics only (from R2 = 0.017 to R2 = 0.030 for internal control beliefs; R2 = 0.056 to R2 = 0.102 for external control beliefs in chance; R2 = 0.006 to R2 = 0.030 for external control beliefs in powerful others). DISCUSSION/CONCLUSION: Findings highlight the importance of access to neighborhood resources for control beliefs across old age and can inform interventions to build up neighborhood characteristics which might be especially helpful in residential areas with high unemployment.


Assuntos
Características da Vizinhança , Características de Residência , Envelhecimento , Feminino , Alemanha , Humanos , Modelos Lineares , Masculino
3.
Z Gerontol Geriatr ; 53(7): 637-643, 2020 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-32945928

RESUMO

In view of the ageing society and the high costs of support and care in private households, the question arises as to what role assistive robots can play. This article focuses on the extent to which robots in nursing are accepted by the adult population in Germany today, as well as the extent to which gender, age, and experience (professional and private) influence this level of acceptance. The analysis carried out for this purpose was based on three representative surveys conducted among a total of over 7000 respondents. Of these surveys two were conducted in the second half of 2017 on behalf of the German Academy of Science and Engineering (acatech) and the life insurance company ERGO, while the third was commissioned by the German Council of Economic Experts (SVRV) in the spring of 2018. An in-depth and cumulative analysis of these surveys and data sets, which the authors helped to design, with respect to assistive robotics has not yet been published. Despite the different application scenarios for assistive care robots, the results of all three surveys are surprisingly consistent: in Germany there is already a significant minority of people who are open to, and would accept nursing care robots as long as they do not replace but rather support traditional human nursing. Roughly one third of the sample differentiated according to age and gender, fundamentally rejected assistance by robots.


Assuntos
Robótica , Atenção à Saúde , Alemanha , Humanos , Inquéritos e Questionários
6.
Psychol Sci ; 29(8): 1291-1298, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29775423

RESUMO

Happiness is considered a highly desirable attribute, but whether or not individuals can actively steer their lives toward greater well-being is an open empirical question. In this study, respondents from a representative German sample reported, in text format, ideas for how they could improve their life satisfaction. We investigated which of these ideas predicted changes in life satisfaction 1 year later. Active pursuits per se-as opposed to statements about external circumstances or fortune-were not associated with changes in life satisfaction ( n = 1,178). However, in line with our preregistered hypothesis, among individuals who described active pursuits ( n = 582), those who described social ideas (e.g., spending more time with friends and family) ended up being more satisfied, and this effect was partly mediated by increased socializing. Our results demonstrate that not all pursuits of happiness are equally successful and corroborate the great importance of social relationships for human well-being.


Assuntos
Felicidade , Satisfação Pessoal , Participação Social , Adulto , Feminino , Alemanha , Humanos , Relações Interpessoais , Masculino , Pessoa de Meia-Idade , Inquéritos e Questionários
7.
J Pers ; 85(4): 454-463, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-26998917

RESUMO

Previous research found that cognitive training increases the Big Five personality trait Openness to Experience during and some weeks after the intervention. The present study investigated whether long-term changes happen in Openness to Experience and other personality traits after an extensive cognitive training of memory and perceptual speed. The intervention group consisted of 204 adults (20-31 years and 65-80 years; 50% female) who received daily 1-hour cognitive training sessions for about 100 days. The control group consisted of 86 adults (21-29 years and 65-82 years; 51% female) who received no cognitive training. All participants answered the NEO Five-Factor Inventory before and 2 years after the cognitive training. Latent change models were applied that controlled for age group (young vs. old) and gender. In the long run, the cognitive training did not affect changes in any facet of Openness to Experience. This was true for young and old participants as well as for men and women. Instead, the cognitive training lowered the general increase of Conscientiousness. Even an extensive cognitive training on memory and perceptual speed does not serve as a sufficient intervention for enduring changes in Openness to Experiences or one of its facets.


Assuntos
Cognição/fisiologia , Memória Episódica , Memória de Curto Prazo/fisiologia , Percepção/fisiologia , Personalidade/fisiologia , Prática Psicológica , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Masculino , Desenvolvimento da Personalidade , Adulto Jovem
8.
Gerontology ; 62(3): 362-70, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26821249

RESUMO

BACKGROUND: Neighborhood characteristics are important determinants of individual health and well-being. For example, characteristics such as noise and pollution affect health directly, while other characteristics affect health and well-being by either providing resources (e.g. social capital in the neighborhood), which individuals can use to cope with health problems, or limiting the use thereof (e.g. crime). This also suggests that there might be age differentials in the impact of these characteristics, since individuals at different stages of life might need different resources. However, there is a lack of empirical evidence on age differentials in associations between well-being, health, and neighborhood characteristics. OBJECTIVE: This paper studies associations between a wide range of neighborhood characteristics with the health and well-being of residents of the greater Berlin area. In particular, we focus on differences in the effects between younger (aged 20-35) and older (aged 60+) residents. METHODS: We used data from the Berlin Aging Study II (312 younger and 993 older residents of the Berlin metropolitan area in Germany). We used survey data on health and well-being, combined these with subjective perceptions of the neighborhood, and geo-referenced indicators on the neighborhood, e.g. amenities (public transport, physicians, and hospitals). RESULTS: The results show that access to public transportation is associated with better outcomes on all measures of health and well-being, and social support is associated with higher life satisfaction and better mental health. There are considerable differences between both age groups: while the associations between access to public transport and health and well-being are similar for both age groups, neighborhood social capital shows stronger associations for older residents. However, the difference is not always statistically significant. CONCLUSION: Having access to services is associated with better health and well-being regardless of age. Local policy makers should focus on lowering barriers to mobility in order to improve the health and well-being of the population. Since the social capital of a neighborhood is associated with better health and well-being among older residents, investments that increase social capital (e.g. community centers) might be warranted in neighborhoods with higher shares of older residents.


Assuntos
Nível de Saúde , Saúde Mental , Características de Residência , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Berlim , Comércio , Síndrome de Cri-du-Chat , Poluição Ambiental , Feminino , Acessibilidade aos Serviços de Saúde , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Ruído , Apoio Social , Meios de Transporte , Adulto Jovem
9.
Gerontology ; 62(3): 311-5, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26820471

RESUMO

Human aging is characterized by large differences between and within older adults. Numerous factors are known to contribute to these differences, including genetic and immunological, somatic and medical, cognitive and behavioral, psychosocial and experiential, as well as socioeconomic and geospatial conditions. Continuing and expanding the scientific objectives of the Berlin Aging Study, the Berlin Aging Study II (BASE-II) seeks to comprehensively describe phenomena associated with aging and old age and to better understand the multiple different underlying factors and their interactions. To this end, BASE-II was established as a multi-institutional project combining and integrating interdisciplinary perspectives ranging from molecular genetics and immunology, geriatric medicine and psychology, to sociology and economics. In this Special Issue, we have compiled seven empirical analyses that feature examples of interdisciplinary insights that BASE-II provides by linking data across multiple levels of analyses at which human functioning and development occur in old age. Here, we provide an overview of the study, note commonalities between BASE-II and earlier studies, and highlight some of its unique qualities.


Assuntos
Envelhecimento/fisiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/genética , Envelhecimento/imunologia , Envelhecimento/psicologia , Estudos de Coortes , Meio Ambiente , Genômica , Humanos , Sistema Imunitário , Pessoa de Meia-Idade , Adulto Jovem
10.
Gerontology ; 62(3): 354-61, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26820135

RESUMO

BACKGROUND: Lifespan psychological and life course sociological perspectives indicate that individual development is shaped by social and historical circumstances. Increases in fluid cognitive performance over the last century are well documented and researchers have begun examining historical trends in personality and subjective well-being in old age. Relatively less is known about secular changes in other key components of psychosocial function among older adults. OBJECTIVE: In the present study, we examined cohort differences in key components of psychosocial function, including subjective age, control beliefs, and perceived social integration, as indicated by loneliness and availability of very close others. METHODS: We compared data obtained 20 years apart in the Berlin Aging Study (in 1990-1993) and the Berlin Aging Study II (in 2013-2014) and identified case-matched cohort groups based on age, gender, cohort-normed education, and marital or partner status (n = 153 in each cohort, mean age = 75 years). In follow-up analyses, we controlled for having lived in former East versus West Germany, physical diseases, cohort-normed household income, cognitive performance, and the presence of a religious affiliation. RESULTS: Consistently across analyses, we found that, relative to the earlier-born BASE cohort (year of birth: mean = 1916; SD = 3.38 years; range = 1901-1922), participants in the BASE-II sample (year of birth: mean = 1939; SD = 3.22 years; range = 1925-1949) reported lower levels of external control beliefs (d = -1.01) and loneliness (d = -0.63). Cohorts did not differ in subjective age, availability of very close others, and internal control beliefs. CONCLUSION: Taken together, our findings suggest that some aspects of psychosocial function of older adults have improved across the two recent decades. We discuss the possible role of sociocultural factors that might have led to the observed set of cohort differences.


Assuntos
Envelhecimento/psicologia , Controle Interno-Externo , Solidão/psicologia , Participação Social/psicologia , Idoso , Idoso de 80 Anos ou mais , Efeito de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
11.
Eur J Public Health ; 26(3): 520-2, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-27056894

RESUMO

To design effective and commonly accepted public health policies against performance-enhancing drugs (PED), it is important to understand general population attitudes. This article elicits PED attitudes in the Berlin population and compares response rates of former athletes (N = 496) with those of non-athletes (N = 1686). In addition, exploiting the natural experiment of the division of Germany, by comparing East (N = 687) to West Berliners (N = 1315), the article studies the long-term impact of state socialisation on PED attitudes. Former West German amateur athletes are a statistically significant 6ppt more likely to believe that athletes can be successful without doping. Former GDR amateur athletes are 8ppt more likely to believe that doping is inevitable in professional sports.


Assuntos
Atletas/psicologia , Atitude Frente a Saúde , Dopagem Esportivo/psicologia , Substâncias para Melhoria do Desempenho , Socialismo , Atletas/estatística & dados numéricos , Dopagem Esportivo/estatística & dados numéricos , Alemanha , Humanos , Inquéritos e Questionários
12.
Int Arch Occup Environ Health ; 87(3): 249-56, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23456220

RESUMO

BACKGROUND: Effort-reward imbalance (ERI) is an established conceptualisation of work stress. Although a validated effort-reward questionnaire is available for public use, many epidemiological studies adopt shortened scales and proxy measures. To examine the agreement between different abbreviated measures and the original instrument, we compared different versions of the effort-reward scales available in 15 European cohort studies participating in the IPD-Work (Individual-participant-data meta-analysis in working populations) consortium. METHODS: Five of the 15 studies provide information on the original ('complete') scales measuring 'effort' and 'reward', whereas the 10 remaining studies used 'partial' scales. To compare different versions of the ERI scales, we analyse individual-level data from 31,790 participants from the five studies with complete scales. RESULTS: Pearson's correlation between partial and complete scales was very high in case of 'effort' (where 2 out of 3 items were used) and very high or high in case of 'reward', if at least 4 items (out of 7) were included. Reward scales composed of 3 items revealed good to satisfactory agreement, and in one case, a reward scale consisting of 2 items only demonstrated a modest, but still acceptable degree of agreement. Sensitivity and specificity of a composite measure, the ratio of effort and reward, comparing partial versus complete scales ranged between 59-93 and 85-99 %, respectively. Complete and partial scales were strongly associated with poor self-rated health. CONCLUSION: Our results support the notion that short proxy measures or partial versions of the original scales can be used to assess effort-reward imbalance.


Assuntos
Emprego/psicologia , Controle Interno-Externo , Saúde Ocupacional/estatística & dados numéricos , Psicometria/instrumentação , Recompensa , Estresse Psicológico/psicologia , Carga de Trabalho/psicologia , Adulto , Estudos de Coortes , Europa (Continente)/epidemiologia , Análise Fatorial , Feminino , Humanos , Satisfação no Emprego , Masculino , Pessoa de Meia-Idade , Psicometria/normas , Autorrelato , Estresse Psicológico/epidemiologia , Inquéritos e Questionários
13.
J Pers Soc Psychol ; 126(2): 346-368, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37498688

RESUMO

Since the new millennium, research in the field of personality development has focused on the stability and change of basic personality traits. Motivational aspects of personality and their longitudinal association with basic traits have received comparably little attention. In this preregistered study, we applied bivariate latent growth curve model to investigated the codevelopment of nine life goals and the Big Five traits. We tested age, perceived control, gender, educational background, and regional socialization as potential moderators of codevelopment. Data came from the German Socio-Economic Panel study (N = 55,040, age range: 18-103 years) and span a study period of 13 years. During this period, the Big Five traits and life goals were assessed four times. Our findings suggest that development in broader life goal domains (e.g., self-fulfillment) is more strongly connected to personality development across the life span, whereas changes in specific goals (e.g., having children) are more closely tied to trait changes during young and middle adulthood. The strongest codevelopment was found between Openness and agentic goals with a focus on personal growth followed by codevelopment between Agreeableness and communal goals. Developmental stage and educational background moderated the codevelopment of Conscientiousness and economic achievement as well as family-related goals. Contrary to the previous research, we found that Neuroticism codeveloped with communal life goals (i.e., having a happy relationship/marriage). Our findings reinforce theoretical frameworks that highlight the role of changing opportunities, constraints, and developmental tasks across adulthood. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Objetivos , Personalidade , Criança , Humanos , Adulto , Adolescente , Adulto Jovem , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Desenvolvimento da Personalidade , Transtornos da Personalidade , Neuroticismo , Estudos Longitudinais
14.
Psychol Aging ; 39(1): 14-30, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-38358694

RESUMO

Research across a number of different areas in psychology has long shown that optimism and pessimism are predictive of a number of important future life outcomes. Despite a vast literature on the correlates and consequences, we know very little about how optimism and pessimism change across adulthood and old age and the sociodemographic factors that are associated with individual differences in such trajectories. In the present study, we conducted (parallel) analyses of standard items from the Life Orientation Test (Scheier & Carver, 1985) in three comprehensive data sets: Two-wave data from both the Berlin Aging Study II (N = 1,423, aged 60-88; M = 70.4, SD = 3.70) and the Midlife in the U.S. Study (N = 1,810 aged 60-84; M = 69.12, SD = 6.47) as well as cross-sectional data from the Survey of Health, Aging, and Retirement (N = 17,087, aged 60-99; M = 70.19, SD = 7.53). Using latent change-regression models and locally weighted smoothing curves revealed that optimism is on average very stable after age 60, with some evidence in Survey of Health, Aging, and Retirement of lowered optimism in very old age. Consistent across the three independent studies, pessimism evinced on average modest increases, ranging between .25 and .50 SD per 10 years of age. Of the sociodemographic factors examined, higher levels of education revealed the most consistent associations with lower pessimism, whereas gender evinced more study-specific findings. We take our results to demonstrate that age-related trajectories and correlates thereof differ for optimism and pessimism. Older adults appear to preserve into older ages those levels of optimistic expectations they have had at 60 years of age and show only modest increases in pessimism. We discuss possible reasons for these findings. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Pessimismo , Humanos , Idoso , Adulto , Estudos Transversais , Envelhecimento , Escolaridade , Individualidade
15.
Psychol Aging ; 39(4): 350-363, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38900502

RESUMO

To check claims of a "loneliness epidemic," we examined whether current cohorts of older adults report higher levels and/or steeper age-related increases in loneliness than earlier-born peers. Specifically, we used 1,068 age-matched longitudinal reports (Mage observations = 79 years, 49% women) of loneliness provided by independent samples recruited in the German city of Berlin in 1990 and 2010, n = 257 participants in the Berlin Aging Study (BASE) and n = 383 participants in Berlin Aging Study II (BASE-II). Using multilevel models that orthogonalize between-person and within-person age effects, we examined how responses to items from the UCLA Loneliness Scale provided by observation-matched cohorts differed with age and across cohorts, and if those differences might be explained by a variety of individual factors. Results revealed that at age 79, the later-born BASE-II cohort reported substantially lower levels of loneliness than the earlier-born BASE cohort (d = -0.84), with cohort differences accounting for more than 14% of the variance in loneliness. Age trajectories, however, were parallel without evidence of cohort differences in rates of within-person age-related changes in loneliness. Differences in gender, education, cognitive functioning, and external control beliefs accounted for the lion's share of cohort-related differences in levels of loneliness. Results show that loneliness among older adults has shifted to markedly lower levels today, but the rate at which loneliness increases with age proceeds similarly as 2 decades ago. Future studies should investigate how psychosocial functioning across the life course is progressing in different sociohistorical contexts and in other age groups, such as younger and middle-aged adults. (PsycInfo Database Record (c) 2024 APA, all rights reserved).


Assuntos
Envelhecimento , Solidão , Humanos , Solidão/psicologia , Feminino , Masculino , Idoso , Idoso de 80 Anos ou mais , Estudos Longitudinais , Envelhecimento/psicologia , Fatores Etários , Berlim
16.
J Nutr Health Aging ; 28(4): 100206, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38460212

RESUMO

OBJECTIVES: Change in body weight during the COVID-19 pandemic as an unintended side effect of lockdown measures has been predominantly reported for younger and middle-aged adults. However, information on older adults for which weight loss is known to result in adverse outcomes, is scarce. In this study we describe the body weight change in older adults before, during, and after the COVID-19 lockdown measures and explore putative associated factors with a focus on the period that includes the first six months of the COVID-19 containment measures. DESIGN: Prospective cohort study with three follow-up examinations over the course of 10 years. SETTING AND PARTICIPANTS: In this study, we analyzed the longitudinal weight change of 472 participants of the Berlin Aging Study II (mean age of 67.5 years at baseline). MEASUREMENTS: Body weight was assessed at four time points. Additionally, differences between subgroups characterized by socio-economic, cognitive, and psychosocial variables as well as morbidity burden, biological age markers (epigenetic clocks, telomere length), and frailty were compared. RESULTS: On average, women and men lost 0.87% (n = 227) and 0.5% (n = 245) of their body weight per year in the study period covering the first six months of the COVID-19 pandemic. Weight loss among men was particularly pronounced among groups characterized by change in physical activity due to COVID-19 lockdown, low positive affect, premature epigenetic age (7-CpG clock), diagnosed metabolic syndrome, and a more masculine gender score (all variables: p < 0.05, n = 245). CONCLUSION: During the COVID-19 pandemic, older participants lost weight with a 2.5-times (women) and 2-times (men) higher rate than what is expected in this age.


Assuntos
COVID-19 , Redução de Peso , Humanos , COVID-19/epidemiologia , COVID-19/prevenção & controle , Masculino , Feminino , Idoso , Estudos Prospectivos , Estudos Longitudinais , Berlim/epidemiologia , Peso Corporal , SARS-CoV-2 , Envelhecimento/fisiologia , Pessoa de Meia-Idade , Fragilidade/epidemiologia , Idoso de 80 Anos ou mais , Pandemias
17.
Qual Life Res ; 22(6): 1189-200, 2013 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-23054492

RESUMO

PURPOSE: To describe the major findings in the literature regarding associations between biological and genetic factors and social functioning, paying special attention to: (1) heritability studies on social functioning and related concepts; (2) hypothesized biological pathways and genetic variants that could be involved in social functioning, and (3) the implications of these results for quality-of-life research. METHODS: A search of Web of Science and PubMed databases was conducted using combinations of the following keywords: genetics, twins, heritability, social functioning, social adjustment, social interaction, and social dysfunction. RESULTS: Variability in the definitions and measures of social functioning was extensive. Moderate to high heritability was reported for social functioning and related concepts, including prosocial behavior, loneliness, and extraversion. Disorders characterized by impairments in social functioning also show substantial heritability. Genetic variants hypothesized to be involved in social functioning are related to the network of brain structures and processes that are known to affect social cognition and behavior. CONCLUSIONS: Better knowledge and understanding about the impact of genetic factors on social functioning is needed to help us to attain a more comprehensive view of health-related quality-of-life (HRQOL) and will ultimately enhance our ability to identify those patients who are vulnerable to poor social functioning.


Assuntos
Genética Comportamental , Nível de Saúde , Relações Interpessoais , Qualidade de Vida , Comportamento Social , Feminino , Variação Genética , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados da Assistência ao Paciente , Ajustamento Social
18.
Proc Natl Acad Sci U S A ; 107(42): 17922-6, 2010 Oct 19.
Artigo em Inglês | MEDLINE | ID: mdl-20921399

RESUMO

Psychologists and economists take contradictory approaches to research on what psychologists call happiness or subjective well-being, and economists call subjective utility. A direct test of the most widely accepted psychological theory, set-point theory, shows it to be flawed. Results are then given, using the economists' newer "choice approach"--an approach also favored by positive psychologists--which yields substantial payoffs in explaining long-term changes in happiness. Data come from the German Socio-Economic Panel (1984-2008), a unique 25-y prospective longitudinal survey. This dataset enables direct tests of theories explaining long-term happiness.


Assuntos
Comportamento de Escolha , Genes , Felicidade , Alemanha , Humanos
19.
PLoS One ; 18(11): e0294896, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38019829

RESUMO

The German Socio-Economic Panel (SOEP) serves a global research community by providing representative annual longitudinal data of respondents living in private households in Germany. The dataset offers a valuable life course panorama, encompassing living conditions, socioeconomic status, familial connections, personality traits, values, preferences, health, and well-being. To amplify research opportunities further, we have extended the SOEP Innovation Sample (SOEP-IS) by collecting genetic data from 2,598 participants, yielding the first genotyped dataset for Germany based on a representative population sample (SOEP-G). The sample includes 107 full-sibling pairs, 501 parent-offspring pairs, and 152 triads, which overlap with the parent-offspring pairs. Leveraging the results from well-powered genome-wide association studies, we created a repository comprising 66 polygenic indices (PGIs) in the SOEP-G sample. We show that the PGIs for height, BMI, and educational attainment capture 22∼24%, 12∼13%, and 9% of the variance in the respective phenotypes. Using the PGIs for height and BMI, we demonstrate that the considerable increase in average height and the decrease in average BMI in more recent birth cohorts cannot be attributed to genetic shifts within the German population or to age effects alone. These findings suggest an important role of improved environmental conditions in driving these changes. Furthermore, we show that higher values in the PGIs for educational attainment and the highest math class are associated with better self-rated health, illustrating complex relationships between genetics, cognition, behavior, socio-economic status, and health. In summary, the SOEP-G data and the PGI repository we created provide a valuable resource for studying individual differences, inequalities, life-course development, health, and interactions between genetic predispositions and the environment.


Assuntos
Sucesso Acadêmico , Estudo de Associação Genômica Ampla , Humanos , Escolaridade , Individualidade , Alemanha/epidemiologia , Fatores Socioeconômicos
20.
Behav Genet ; 42(2): 221-33, 2012 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21858515

RESUMO

Findings from many behavioral genetic studies utilizing the classical twin design suggest that genetic and non-shared environmental effects play a significant role in human personality traits. This study focuses on the methodological advantages of extending the sampling frame to include multiple dyads of relatives. We investigated the sensitivity of heritability estimates to the inclusion of sibling pairs, mother-child pairs and grandparent-grandchild pairs from the German Socio-Economic Panel Study in addition to a classical German twin sample consisting of monozygotic- and dizygotic twins. The resulting dataset contained 1.308 pairs, including 202 monozygotic and 147 dizygotic twin pairs, along with 419 sibling pairs, 438 mother-child dyads, and 102 grandparent-child dyads. This genetically sensitive multi-group design allowed the simultaneous testing of additive and non-additive genetic, common and specific environmental effects, including cultural transmission and twin-specific environmental influences. Using manifest and latent modeling of phenotypes (i.e., controlling for measurement error), we compare results from the extended sample with those from the twin sample alone and discuss implications for future research.


Assuntos
Modelos Genéticos , Personalidade/genética , Projetos de Pesquisa , Características Culturais , Meio Ambiente , Família , Feminino , Humanos , Masculino , Mães , Fenótipo , Irmãos , Gêmeos Dizigóticos/genética , Gêmeos Monozigóticos/genética
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