Detalhe da pesquisa
1.
Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.
Alzheimers Dement
; 17(9): 1487-1498, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938131
2.
A quantitative systems pharmacology model of colonic motility with applications in drug development.
J Pharmacokinet Pharmacodyn
; 46(5): 485-498, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31432345
3.
A Quantitative Systems Pharmacology Model Describing the Cellular Kinetic-Pharmacodynamic Relationship for a Live Biotherapeutic Product to Support Microbiome Drug Development.
Clin Pharmacol Ther
; 114(3): 633-643, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37218407
4.
Quantitative modeling predicts competitive advantages of a next generation anti-NKG2A monoclonal antibody over monalizumab for the treatment of cancer.
CPT Pharmacometrics Syst Pharmacol
; 10(3): 220-229, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33501768
5.
A systems pharmacology model for gene therapy in sickle cell disease.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 696-708, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34139105
6.
Virtual clinical trial simulations for a novel KRASG12C inhibitor (ASP2453) in non-small cell lung cancer.
CPT Pharmacometrics Syst Pharmacol
; 10(8): 864-877, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34043291
7.
Epi-allelic Erk1 and Erk2 knockdown series for quantitative analysis of T cell Erk regulation and IL-2 production.
Mol Immunol
; 44(12): 3085-91, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17418417
8.
Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.
Clin Cancer Res
; 11(11): 4259-65, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15930365
9.
Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I.
Genetics
; 160(2): 805-13, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11861581
10.
Seribantumab, an Anti-ERBB3 Antibody, Delays the Onset of Resistance and Restores Sensitivity to Letrozole in an Estrogen Receptor-Positive Breast Cancer Model.
Mol Cancer Ther
; 14(11): 2642-52, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26310543
11.
Quantitative network signal combinations downstream of TCR activation can predict IL-2 production response.
J Immunol
; 178(8): 4984-92, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17404280