Detalhe da pesquisa
1.
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3.
Bioorg Med Chem Lett
; 99: 129617, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199328
2.
STOPLIGHT: A Hit Scoring Calculator.
J Chem Inf Model
; 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38768560
3.
Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals.
J Proteome Res
; 22(10): 3159-3177, 2023 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634194
4.
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells.
Molecules
; 28(7)2023 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37049713
5.
The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification.
Int J Mol Sci
; 22(2)2021 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33429995
6.
Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.
Tetrahedron Lett
; 61(38)2020 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33012852
7.
In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds.
Molecules
; 25(2)2020 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31941153
8.
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK).
Molecules
; 24(22)2019 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31698822
9.
1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) Inhibitors.
Molecules
; 23(5)2018 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783765
10.
Synthesis of 5-Benzylamino and 5-Alkylamino-Substituted Pyrimido[4,5-c]quinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity.
Pharmaceuticals (Basel)
; 17(3)2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38543092
11.
Illuminating function of the understudied druggable kinome.
Drug Discov Today
; 29(3): 103881, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38218213
12.
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships.
Eur J Med Chem
; 271: 116357, 2024 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38636130
13.
Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
bioRxiv
; 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38562906
14.
Development of Cell Permeable NanoBRET Probes for the Measurement of PLK1 Target Engagement in Live Cells.
bioRxiv
; 2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865333
15.
Identification of 4-(6-((2-methoxyphenyl)amino)pyrazin-2-yl)benzoic acids as CSNK2A inhibitors with antiviral activity and improved selectivity over PIM3.
bioRxiv
; 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106118
16.
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines Toward the Development of an In Vivo Chemical Probe for CSNK2A.
bioRxiv
; 2023 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292607
17.
Optimization of 3-Cyano-7-cyclopropylamino-pyrazolo[1,5-a]pyrimidines toward the Development of an In Vivo Chemical Probe for CSNK2A.
ACS Omega
; 8(42): 39546-39561, 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37901516
18.
Fused Tetrahydroquinolines Are Interfering with Your Assay.
J Med Chem
; 66(21): 14434-14446, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37874947
19.
Dual Inhibition of Mycobacterium tuberculosis and the Host TGFBR1 by an Anilinoquinazoline.
J Med Chem
; 66(21): 14724-14734, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37871287
20.
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships.
bioRxiv
; 2023 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38234837