Detalhe da pesquisa
1.
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype.
Genet Med
; 23(9): 1636-1647, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34145395
2.
Predicting kinase inhibitors using bioactivity matrix derived informer sets.
PLoS Comput Biol
; 15(8): e1006813, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381559
3.
PP2A as a master regulator of the cell cycle.
Crit Rev Biochem Mol Biol
; 51(3): 162-84, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26906453
4.
A screen for kinase inhibitors identifies antimicrobial imidazopyridine aminofurazans as specific inhibitors of the Listeria monocytogenes PASTA kinase PrkA.
J Biol Chem
; 292(41): 17037-17045, 2017 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821610
5.
In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with ß-Lactams To Inhibit Mycobacterial Growth.
Mol Pharm
; 15(11): 5410-5426, 2018 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30285456
6.
Dissecting the Role of E2 Protein Domains in Alphavirus Pathogenicity.
J Virol
; 90(5): 2418-33, 2015 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26676771
7.
Engineering Selectivity for Reduced Toxicity of Bacterial Kinase Inhibitors Using Structure-Guided Medicinal Chemistry.
ACS Med Chem Lett
; 12(2): 228-235, 2021 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35035774
8.
Purification of Target Proteins from Native Tissues: CCT Complex from Bovine Testes and PP2Ac from Porcine Brains.
Methods Mol Biol
; 1788: 73-88, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247302
9.
GW779439X and Its Pyrazolopyridazine Derivatives Inhibit the Serine/Threonine Kinase Stk1 and Act As Antibiotic Adjuvants against ß-Lactam-Resistant Staphylococcus aureus.
ACS Infect Dis
; 4(10): 1508-1518, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30059625
10.
Comparative analysis of the human and zebrafish kinomes: focus on the development of kinase inhibitors.
Trends Cell Mol Biol
; 10: 49-75, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27011661
11.
Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.
Cell Res
; 24(2): 190-203, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24100351
12.
Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation.
PLoS One
; 9(1): e86955, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24466300
13.
Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res
; 23(7): 931-46, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23752926