Detalhe da pesquisa
1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612233
2.
Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J Biol Chem
; 292(16): 6810-6820, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28235803
3.
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δ.
J Biol Chem
; 290(13): 8439-46, 2015 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631052
4.
Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assembly.
Biochemistry
; 54(13): 2240-8, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25774576
5.
Design, creation and in vitro testing of a reduced immunogenicity humanized anti-CD25 monoclonal antibody that retains functional activity.
Protein Eng Des Sel
; 32(12): 543-554, 2019 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32725169
6.
The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM.
J Mol Biol
; 431(7): 1440-1459, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30753871
7.
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model.
Nat Med
; 25(9): 1377-1384, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501601
8.
ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J Clin Invest
; 128(10): 4485-4500, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30024858
9.
A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo.
J Transl Med
; 5: 61, 2007 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18042290
10.
Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A.
J Med Chem
; 60(3): 1000-1017, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28075591
11.
Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent.
J Exp Ther Oncol
; 5(4): 273-86, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-17024968
12.
Antibodies to TWEAK receptor inhibit human tumor growth through dual mechanisms.
Clin Cancer Res
; 16(2): 497-508, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20068083
13.
Volociximab, a chimeric integrin alpha5beta1 antibody, inhibits the growth of VX2 tumors in rabbits.
Invest New Drugs
; 26(1): 7-12, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17786386