Detalhe da pesquisa
1.
Deficiency of UCHL1 results in insufficient decidualization accompanied by impaired dNK modulation and eventually miscarriage.
J Transl Med
; 22(1): 478, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38769534
2.
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects.
Nat Biotechnol
; 41(1): 108-119, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35953673
3.
Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editor.
Protein Cell
; 14(6): 416-432, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37285261
4.
Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing.
Nat Commun
; 14(1): 2046, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37041195
5.
Inflammation-induced inhibition of chaperone-mediated autophagy maintains the immunosuppressive function of murine mesenchymal stromal cells.
Cell Mol Immunol
; 18(6): 1476-1488, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31900460
6.
The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase.
Theranostics
; 10(13): 6048-6060, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483437
7.
Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism.
EBioMedicine
; 39: 540-551, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30578080
8.
The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation.
J Exp Clin Cancer Res
; 37(1): 258, 2018 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30359286
9.
The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells.
Cell Death Dis
; 9(5): 459, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29686406
10.
An engineered xCas12i with high activity, high specificity, and broad PAM range.
Protein Cell
; 14(7): 538-543, 2023 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37378659
11.
Determination of AZD3759 in rat plasma and brain tissue by LC-MS/MS and its application in pharmacokinetic and brain distribution studies.
J Pharm Biomed Anal
; 140: 362-366, 2017 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28399431
12.
Development and Validation of a Rapid and Sensitive LC-MS/MS Method for the Pharmacokinetic Study of Osimertinib in Rats.
J AOAC Int
; 100(6): 1771-1775, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28534470
13.
RAS protein activator-like 1 is functionally involved in hypoxia resistance in breast cancer cells by targeting hypoxia inducible factor-1α.
Oncol Lett
; 14(3): 3839-3845, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927155
14.
Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver.
Protein Cell
; 11(7): 518-524, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32185621
15.
Synthesis of some 5-phenylisoxazole-3-carboxylic acid derivatives as potent xanthine oxidase inhibitors.
Eur J Med Chem
; 45(6): 2663-70, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20189693