Detalhe da pesquisa
1.
Comparison of the incidence of vancomycin-associated nephrotoxicity following the change from trough-guided dosing to AUC-guided doing using trough-only data.
J Antimicrob Chemother
; 78(12): 2933-2937, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37889089
2.
Fluorescence properties of retinoid X receptor antagonist NEt-SB.
Bioorg Med Chem Lett
; 31: 127666, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33152377
3.
The Mitochondrial Respiratory Chain Maintains the Photosynthetic Electron Flow in Arabidopsis thaliana Leaves under High-Light Stress.
Plant Cell Physiol
; 61(2): 283-295, 2020 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31603217
4.
Fluorine-18 (18F)-labeled retinoidâ¯xâ¯receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands.
Bioorg Med Chem
; 27(14): 3128-3134, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176570
5.
Ligand Screening System for the RXRα Heterodimer Using the Fluorescence RXR Agonist CU-6PMN.
ACS Med Chem Lett
; 14(3): 291-296, 2023 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923911
6.
Effectiveness of countermeasure for polypharmacy by multidisciplinary team review in patients with diabetes mellitus.
J Diabetes Investig
; 14(10): 1202-1208, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37357565
7.
Feasibility of structural modification of retinoid X receptor agonists to separate blood glucose-lowering action from adverse effects: studies in KKA(y) type 2 diabetes model mice.
Biol Pharm Bull
; 35(4): 629-33, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22466572
8.
Replacement of the hydrophobic part of 9-cis-retinoic acid with cyclic terpenoid moiety results in RXR-selective agonistic activity.
Bioorg Med Chem
; 19(9): 2939-49, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21489804
9.
Discovery of a "Gatekeeper" Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers.
J Med Chem
; 64(1): 430-439, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356247
10.
Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay.
ACS Med Chem Lett
; 12(6): 1024-1029, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141088
11.
Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343.
J Med Chem
; 64(1): 861-870, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378197
12.
Modification at the acidic domain of RXR agonists has little effect on permissive RXR-heterodimer activation.
Bioorg Med Chem Lett
; 20(17): 5139-42, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20656484
13.
Fluorescent retinoid X receptor ligands for fluorescence polarization assay.
Bioorg Med Chem Lett
; 20(17): 5143-6, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20667726
14.
Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening.
J Med Chem
; 62(19): 8809-8818, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483660
15.
Synthesis of 11C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof.
J Med Chem
; 60(16): 7139-7145, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28753292
16.
Positron emission tomography to elucidate pharmacokinetic differences of regioisomeric retinoid x receptor agonists.
ACS Med Chem Lett
; 6(3): 334-8, 2015 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25815156
17.
RXR partial agonist produced by side chain repositioning of alkoxy RXR full agonist retains antitype 2 diabetes activity without the adverse effects.
J Med Chem
; 58(2): 912-26, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486327
18.
Retinoid X receptor ligands: a patent review (2007 - 2013).
Expert Opin Ther Pat
; 24(4): 443-52, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24456080
19.
Correction to Synthesis of 11C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Trialkyltin Precursor and PET Imaging Thereof.
J Med Chem
; 62(9): 4780-4781, 2019 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002501
20.
Mechanism of retinoid X receptor partial agonistic action of 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid and structural development to increase potency.
J Med Chem
; 56(5): 1865-77, 2013 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23391145