Detalhe da pesquisa
1.
Development and validation of an HPLC coupled with tandem mass spectrometry method for the determination of HSK7653, a novel super long-acting dipeptidyl peptidase-4 inhibitor, in human plasma and urine and its application to a pharmacokinetic study.
Biomed Chromatogr
; 37(5): e5607, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36802077
2.
Model-informed drug development: The mechanistic HSK3486 physiologically based pharmacokinetic model informing dose decisions in clinical trials of specific populations.
Biopharm Drug Dispos
; 44(3): 259-273, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313580
3.
Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects.
Br J Clin Pharmacol
; 87(7): 2711-2722, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33068053
4.
Population-based meta-analysis of chloroquine: informing chloroquine pharmacokinetics in COVID-19 patients.
Eur J Clin Pharmacol
; 77(4): 583-593, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33188451
5.
Physiologically based pharmacokinetic model of renally cleared antibacterial drugs in Chinese renal impairment patients.
Biopharm Drug Dispos
; 42(1): 24-34, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340419
6.
In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Clin Infect Dis
; 71(15): 732-739, 2020 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32150618
7.
Early metabolic characterization of brain tissues after whole body radiation based on gas chromatography-mass spectrometry in a rat model.
Biomed Chromatogr
; 33(3): e4448, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30499600
8.
Development of a simple HPLC-MS/MS method to simultaneously determine teriflunomide and its metabolite in human plasma and urine: Application to clinical pharmacokinetic study of teriflunomide sodium and leflunomide.
Biomed Chromatogr
; 33(3): e4420, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30362147
9.
Bacteria and poisonous plants were the primary causative hazards of foodborne disease outbreak: a seven-year survey from Guangxi, South China.
BMC Public Health
; 18(1): 519, 2018 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29669556
10.
A high-performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of imigliptin, its five metabolites and alogliptin in human plasma and urine and its application to a multiple-dose pharmacokinetic study.
Biomed Chromatogr
; 32(11): e4324, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29952007
11.
Reply to Wolowich and Kwon.
Clin Infect Dis
; 72(9): 1678-1680, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32613227
12.
Response to Jia and Wang.
Clin Infect Dis
; 73(2): 352-353, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33170206
13.
The multiple roles of autophagy in uveal melanoma and the microenvironment.
J Cancer Res Clin Oncol
; 150(3): 121, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467935
14.
Dose Prediction and Pharmacokinetic Simulation of XZP-5610, a Small Molecule for NASH Therapy, Using Allometric Scaling and Physiologically Based Pharmacokinetic Models.
Pharmaceuticals (Basel)
; 17(3)2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38543155
15.
Model-based exploration of the rationality of off-label use of cetirizine in Chinese pediatric patients: a prospective cohort study.
Front Pharmacol
; 15: 1322788, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38549675
16.
Development of a Physiologically Based Pharmacokinetic Population Model for Diabetic Patients and its Application to Understand Disease-drug-drug Interactions.
Clin Pharmacokinet
; 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38819713
17.
Integrated models of population pharmacokinetics and exposure response to optimize dosage regimen for anaprazole sodium in duodenal ulcer.
Eur J Pharm Sci
; 198: 106781, 2024 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703917
18.
Population Pharmacokinetic/Pharmacodynamic Analysis of the Glucokinase Activator PB201 in Healthy Volunteers and Patients with Type 2 Diabetes Mellitus: Facilitating the Clinical Development of PB201 in China.
Clin Pharmacokinet
; 63(1): 93-108, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37985591
19.
Model informed drug development: HSK21542 PBPK model supporting dose decisions in specific populations.
Eur J Pharm Sci
; 196: 106763, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38599505
20.
A model-based meta analysis study of sodium glucose co-transporter-2 inhibitors.
CPT Pharmacometrics Syst Pharmacol
; 12(4): 487-499, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36890732