Pesquisa | BVS Integralidade em Saúde

1.

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells.

Bu, Wei; Joyce, M Gordon; Nguyen, Hanh; Banh, Dalton V; Aguilar, Fiona; Tariq, Zeshan; Yap, Moh Lan; Tsujimura, Yusuke; Gillespie, Rebecca A; Tsybovsky, Yaroslav; Andrews, Sarah F; Narpala, Sandeep R; McDermott, Adrian B; Rossmann, Michael G; Yasutomi, Yasuhiro; Nabel, Gary J; Kanekiyo, Masaru; Cohen, Jeffrey I.

Immunity ; 50(5): 1305-1316.e6, 2019 05 21.

Artigo em Inglês | MEDLINE | ID: mdl-30979688

2.

COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions.

Urano, Emiko; Okamura, Tomotaka; Ono, Chikako; Ueno, Shiori; Nagata, Satoshi; Kamada, Haruhiko; Higuchi, Mahoko; Furukawa, Mugi; Kamitani, Wataru; Matsuura, Yoshiharu; Kawaoka, Yoshihiro; Yasutomi, Yasuhiro.

Proc Natl Acad Sci U S A ; 118(43)2021 10 26.

Artigo em Inglês | MEDLINE | ID: mdl-34625475

3.

Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient-Derived Cell Lines for HTLV-1 Infection.

Urano, Emiko; Ueda, Kayoko; Higuchi, Mahoko; Furukawa, Mugi; Okamura, Tomotaka; Tanaka, Yuetsu; Yasutomi, Yasuhiro.

J Virol ; 96(22): e0133922, 2022 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-36314828

4.

Development of a novel Macaque-Tropic HIV-1 adapted to cynomolgus macaques.

Ode, Hirotaka; Saito, Akatsuki; Washizaki, Ayaka; Seki, Yohei; Yoshida, Takeshi; Harada, Shigeyoshi; Ishii, Hiroshi; Shioda, Tatsuo; Yasutomi, Yasuhiro; Matano, Tetsuro; Miura, Tomoyuki; Akari, Hirofumi; Iwatani, Yasumasa.

J Gen Virol ; 103(10)2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-36205476

5.

CD8 T Cells Show Protection against Highly Pathogenic Simian Immunodeficiency Virus (SIV) after Vaccination with SIV Gene-Expressing BCG Prime and Vaccinia Virus/Sendai Virus Vector Boosts.

Kato, Seiichi; Shida, Hisatoshi; Okamura, Tomotaka; Zhang, Xianfeng; Miura, Tomoyuki; Mukai, Tetsu; Inoue, Makoto; Shu, Tsugumine; Naruse, Taeko K; Kimura, Akinori; Yasutomi, Yasuhiro; Matsuo, Kazuhiro.

J Virol ; 95(4)2021 01 28.

Artigo em Inglês | MEDLINE | ID: mdl-33087465

6.

Vaccination with Intradermal Bacillus Calmette-Guérin Provides Robust Protection against Extrapulmonary Tuberculosis but Not Pulmonary Infection in Cynomolgus Macaques.

Tsujimura, Yusuke; Shiogama, Yumiko; Soma, Shogo; Okamura, Tomotaka; Takano, Junichiro; Urano, Emiko; Murakata, Yoshiko; Kawano, Akira; Yamakawa, Natsuko; Asaka, Masamitsu N; Matsuo, Kazuhiro; Yasutomi, Yasuhiro.

J Immunol ; 205(11): 3023-3036, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33097574

7.

Repeated Intravaginal Inoculation of Zika Virus Protects Cynomolgus Monkeys from Subcutaneous Superchallenge.

Shofa, Maya; Okamura, Tomotaka; Urano, Emiko; Matsuura, Yoshiharu; Yasutomi, Yasuhiro; Saito, Akatsuki.

Int J Mol Sci ; 23(22)2022 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-36430481

8.

SOCS1 Antagonist-Expressing Recombinant Bacillus Calmette-Guérin Enhances Antituberculosis Protection in a Mouse Model.

Mizuno, Satoru; Soma, Shogo; Inada, Hiroyasu; Kanuma, Tomohiro; Matsuo, Kazuhiro; Yasutomi, Yasuhiro.

J Immunol ; 203(1): 188-197, 2019 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-31101668

9.

A New Mouse Model of Chronic Myocarditis Induced by Recombinant Bacille Calmette-Guèrin Expressing a T-Cell Epitope of Cardiac Myosin Heavy Chain-α.

Tajiri, Kazuko; Imanaka-Yoshida, Kyoko; Tsujimura, Yusuke; Matsuo, Kazuhiro; Hiroe, Michiaki; Aonuma, Kazutaka; Ieda, Masaki; Yasutomi, Yasuhiro.

Int J Mol Sci ; 22(2)2021 Jan 14.

Artigo em Inglês | MEDLINE | ID: mdl-33466825

10.

Elevated Membrane Cholesterol Disrupts Lysosomal Degradation to Induce ß-Amyloid Accumulation: The Potential Mechanism Underlying Augmentation of ß-Amyloid Pathology by Type 2 Diabetes Mellitus.

Takeuchi, Shingo; Ueda, Naoya; Suzuki, Keiko; Shimozawa, Nobuhiro; Yasutomi, Yasuhiro; Kimura, Nobuyuki.

Am J Pathol ; 189(2): 391-404, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30448407

11.

A unique nanoparticulate TLR9 agonist enables a HA split vaccine to confer FcÎ³R-mediated protection against heterologous lethal influenza virus infection.

Yamamoto, Takuya; Masuta, Yuji; Momota, Masatoshi; Kanekiyo, Masaru; Kanuma, Tomohiro; Takahama, Shoukichi; Moriishi, Eiko; Yasutomi, Yasuhiro; Saito, Takashi; Graham, Barney S; Takahashi, Yoshimasa; Ishii, Ken J.

Int Immunol ; 31(2): 81-90, 2019 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-30535055

12.

An Antigen-Free, Plasmacytoid Dendritic Cell-Targeting Immunotherapy To Bolster Memory CD8⁺ T Cells in Nonhuman Primates.

Masuta, Yuji; Yamamoto, Takuya; Natsume-Kitatani, Yayoi; Kanuma, Tomohiro; Moriishi, Eiko; Kobiyama, Kouji; Mizuguchi, Kenji; Yasutomi, Yasuhiro; Ishii, Ken J.

J Immunol ; 200(6): 2067-2075, 2018 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-29431693

13.

Intranasal vaccination with HBs and HBc protein combined with carboxyl vinyl polymer induces strong neutralizing antibody, anti-HBs IgA, and IFNG response.

Sanada, Takahiro; Yamamoto, Naoki; Kayesh, Mohammad Enamul Hoque; Tsukiyama-Kohara, Kyoko; Hasegawa, Hideki; Miyazaki, Takashi; Takano, Jun-Ichiro; Shiogama, Yumiko; Yasutomi, Yasuhiro; Goh, Yasumasa; Yoshida, Osamu; Hiasa, Yoichi; Kohara, Michinori.

Biochem Biophys Res Commun ; 520(1): 86-92, 2019 11 26.

Artigo em Inglês | MEDLINE | ID: mdl-31582218

14.

Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice.

Nagatake, Takahiro; Suzuki, Hidehiko; Hirata, So-Ichiro; Matsumoto, Naomi; Wada, Yasuko; Morimoto, Sakiko; Nasu, Ayaka; Shimojou, Michiko; Kawano, Mitsuo; Ogami, Kentaro; Tsujimura, Yusuke; Kuroda, Etsushi; Iijima, Norifumi; Hosomi, Koji; Ishii, Ken J; Nosaka, Tetsuya; Yasutomi, Yasuhiro; Kunisawa, Jun.

Int Immunol ; 30(10): 471-481, 2018 09 25.

Artigo em Inglês | MEDLINE | ID: mdl-30011025

15.

The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.

Nagatake, Takahiro; Shiogama, Yumiko; Inoue, Asuka; Kikuta, Junichi; Honda, Tetsuya; Tiwari, Prabha; Kishi, Takayuki; Yanagisawa, Atsushi; Isobe, Yosuke; Matsumoto, Naomi; Shimojou, Michiko; Morimoto, Sakiko; Suzuki, Hidehiko; Hirata, So-Ichiro; Steneberg, Pär; Edlund, Helena; Aoki, Junken; Arita, Makoto; Kiyono, Hiroshi; Yasutomi, Yasuhiro; Ishii, Masaru; Kabashima, Kenji; Kunisawa, Jun.

J Allergy Clin Immunol ; 142(2): 470-484.e12, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29288079

16.

Successful Inflammation Imaging of Non-Human Primate Hearts Using an Antibody Specific for Tenascin-C.

Ageyama, Naohide; Kurosawa, Hiroyuki; Fujimoto, Ousuke; Uehara, Tomoya; Hiroe, Michiaki; Arano, Yasushi; Yoshida, Toshimichi; Yasutomi, Yasuhiro; Imanaka-Yoshida, Kyoko.

Int Heart J ; 60(1): 151-158, 2019 Jan 25.

Artigo em Inglês | MEDLINE | ID: mdl-30464121

17.

Primary Role of Suppressor of Cytokine Signaling 1 in Mycobacterium bovis BCG Infection.

Soma, Shogo; Kawai, Satoru; Inada, Hiroyasu; Watanabe, Kenta; Mizuno, Satoru; Kato, Seiichi; Matsuo, Kazuhiro; Yasutomi, Yasuhiro.

Infect Immun ; 86(11)2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30181351

18.

Relationship between menarche and fertility in long-tailed macaques (Macaca fascicularis).

Kobayashi, Maiko; Koyama, Takamasa; Yasutomi, Yasuhiro; Sankai, Tadashi.

J Reprod Dev ; 64(4): 337-342, 2018 Aug 20.

Artigo em Inglês | MEDLINE | ID: mdl-29848903

19.

Okamura, Tomotaka; Yasutomi, Yasuhiro.

Uirusu ; 72(2): 167-170, 2023.

Artigo em Japonês | MEDLINE | ID: mdl-38220205

20.

Dynein Dysfunction Reproduces Age-Dependent Retromer Deficiency: Concomitant Disruption of Retrograde Trafficking Is Required for Alteration in ß-Amyloid Precursor Protein Metabolism.

Kimura, Nobuyuki; Samura, Eriko; Suzuki, Keiko; Okabayashi, Sachi; Shimozawa, Nobuhiro; Yasutomi, Yasuhiro.

Am J Pathol ; 186(7): 1952-1966, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27179390

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