Pesquisa | BVS Integralidade em Saúde

1.

Loss of chromatin structural integrity is a source of stress during aging.

Yu, Ruofan; McCauley, Brenna; Dang, Weiwei.

Hum Genet ; 139(3): 371-380, 2020 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-31900586

2.

SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence.

Yu, An; Yu, Ruofan; Liu, Haiying; Ge, Chenliang; Dang, Weiwei.

Geroscience ; 46(1): 1107-1127, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37420111

3.

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

Yu, Yang; Wang, Xin; Fox, Jordan; Yu, Ruofan; Thakre, Pilendra; McCauley, Brenna; Nikoloutsos, Nicolas; Li, Qian; Hastings, P J; Dang, Weiwei; Chen, Kaifu; Ira, Grzegorz.

Res Sq ; 2024 Jan 05.

Artigo em Inglês | MEDLINE | ID: mdl-38260641

4.

CTCF/cohesin organize the ground state of chromatin-nuclear speckle association.

Yu, Ruofan; Roseman, Shelby; Siegenfeld, Allison P; Nguyen, Son C; Joyce, Eric F; Liau, Brian B; Krantz, Ian D; Alexander, Katherine A; Berger, Shelley L.

bioRxiv ; 2023 Oct 24.

Artigo em Inglês | MEDLINE | ID: mdl-37961560

5.

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

Yu, Yang; Wang, Xin; Fox, Jordan; Yu, Ruofan; Thakre, Pilendra; McCauley, Brenna; Nikoloutsos, Nicolas; Li, Qian; Hastings, P J; Dang, Weiwei; Chen, Kaifu; Ira, Grzegorz.

bioRxiv ; 2023 Dec 13.

Artigo em Inglês | MEDLINE | ID: mdl-38168242

6.

Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer.

Alexander, Katherine A; Yu, Ruofan; Skuli, Nicolas; Coffey, Nathan J; Nguyen, Son; Faunce, Christine; Huang, Hua; Dardani, Ian P; Good, Austin L; Lim, Joan; Li, Catherine; Biddle, Nicholas; Joyce, Eric F; Raj, Arjun; Lee, Daniel; Keith, Brian; Simon, M Celeste; Berger, Shelley L.

bioRxiv ; 2023 Sep 16.

Artigo em Inglês | MEDLINE | ID: mdl-37745397

7.

A quantitative yeast aging proteomics analysis reveals novel aging regulators.

Sun, Yu; Yu, Ruofan; Guo, Hao-Bo; Qin, Hong; Dang, Weiwei.

Geroscience ; 43(5): 2573-2593, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34241809

8.

Adiponectin promotes myogenic differentiation via a Mef2C-AdipoR1 positive feedback loop.

Yu, An; Zheng, Yu; Gong, Yuqing; Yu, Ruofan; Yang, Zaiqing; Chen, Xiaodong.

Gene ; 771: 145380, 2021 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-33359123

9.

Complementary performances of convolutional and capsule neural networks on classifying microfluidic images of dividing yeast cells.

Ghafari, Mehran; Clark, Justin; Guo, Hao-Bo; Yu, Ruofan; Sun, Yu; Dang, Weiwei; Qin, Hong.

PLoS One ; 16(3): e0246988, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33730031

10.

Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells.

McCauley, Brenna S; Sun, Luyang; Yu, Ruofan; Lee, Minjung; Liu, Haiying; Leeman, Dena S; Huang, Yun; Webb, Ashley E; Dang, Weiwei.

Nat Aging ; 1(8): 684-697, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34746802

11.

Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism.

Yu, Ruofan; Cao, Xiaohua; Sun, Luyang; Zhu, Jun-Yi; Wasko, Brian M; Liu, Wei; Crutcher, Emeline; Liu, Haiying; Jo, Myeong Chan; Qin, Lidong; Kaeberlein, Matt; Han, Zhe; Dang, Weiwei.

Nat Commun ; 12(1): 1981, 2021 03 31.

Artigo em Inglês | MEDLINE | ID: mdl-33790287

12.

Measuring the Replicative Lifespan of Saccharomyces cerevisiae Using the HYAA Microfluidic Platform.

Yu, Ruofan; Jo, Myeong Chan; Dang, Weiwei.

Methods Mol Biol ; 2144: 1-6, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32410020

13.

Cellular response to moderate chromatin architectural defects promotes longevity.

Yu, Ruofan; Sun, Luyang; Sun, Yu; Han, Xin; Qin, Lidong; Dang, Weiwei.

Sci Adv ; 5(7): eaav1165, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31309140

14.

Chromatin Architectural Changes during Cellular Senescence and Aging.

Sun, Luyang; Yu, Ruofan; Dang, Weiwei.

Genes (Basel) ; 9(4)2018 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-29659513

15.

Building bridges.

Yu, Ruofan.

Science ; 369(6504): 738, 2020 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-32764074

16.

A formalized design process for bacterial consortia that perform logic computing.

Ji, Weiyue; Shi, Handuo; Zhang, Haoqian; Sun, Rui; Xi, Jingyi; Wen, Dingqiao; Feng, Jingchen; Chen, Yiwei; Qin, Xiao; Ma, Yanrong; Luo, Wenhan; Deng, Linna; Lin, Hanchi; Yu, Ruofan; Ouyang, Qi.

PLoS One ; 8(2): e57482, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23468999

17.

Gearing up for survival - HSP-containing granules accumulate in quiescent cells and promote survival.

Yu, Ruofan; Dang, Weiwei.

Microb Cell ; 3(3): 95-96, 2016 Mar 06.

Artigo em Inglês | MEDLINE | ID: mdl-28362009

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Loss of chromatin structural integrity is a source of stress during aging.

SIRT1 safeguards adipogenic differentiation by orchestrating anti-oxidative responses and suppressing cellular senescence.

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

CTCF/cohesin organize the ground state of chromatin-nuclear speckle association.

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA.

Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer.

A quantitative yeast aging proteomics analysis reveals novel aging regulators.

Adiponectin promotes myogenic differentiation via a Mef2C-AdipoR1 positive feedback loop.

Complementary performances of convolutional and capsule neural networks on classifying microfluidic images of dividing yeast cells.

Altered Chromatin States Drive Cryptic Transcription in Aging Mammalian Stem Cells.

Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism.

Measuring the Replicative Lifespan of Saccharomyces cerevisiae Using the HYAA Microfluidic Platform.

Cellular response to moderate chromatin architectural defects promotes longevity.

Chromatin Architectural Changes during Cellular Senescence and Aging.

Building bridges.

A formalized design process for bacterial consortia that perform logic computing.

Gearing up for survival - HSP-containing granules accumulate in quiescent cells and promote survival.