Pesquisa | BVS Integralidade em Saúde

1.

Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.

Ast, Tslil; Meisel, Joshua D; Patra, Shachin; Wang, Hong; Grange, Robert M H; Kim, Sharon H; Calvo, Sarah E; Orefice, Lauren L; Nagashima, Fumiaki; Ichinose, Fumito; Zapol, Warren M; Ruvkun, Gary; Barondeau, David P; Mootha, Vamsi K.

Cell ; 177(6): 1507-1521.e16, 2019 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-31031004

2.

Development of nitric oxide generators to produce high-dose nitric oxide for inhalation therapy.

Yu, Binglan; Wanderley, Hatus V; Gianni, Stefano; Carroll, Ryan W; Ichinose, Fumito; Zapol, Warren M; Berra, Lorenzo.

Nitric Oxide ; 138-139: 17-25, 2023 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-37277062

3.

Matrix Gla Protein Levels Are Associated With Arterial Stiffness and Incident Heart Failure With Preserved Ejection Fraction.

Malhotra, Rajeev; Nicholson, Christopher J; Wang, Dongyu; Bhambhani, Vijeta; Paniagua, Samantha; Slocum, Charles; Sigurslid, Haakon H; Lino Cardenas, Christian L; Li, Rebecca; Boerboom, Sophie L; Chen, Yin-Ching; Hwang, Shih-Jen; Yao, Chen; Ichinose, Fumito; Bloch, Donald B; Lindsay, Mark E; Lewis, Gregory D; Aragam, Jayashri R; Hoffmann, Udo; Mitchell, Gary F; Hamburg, Naomi M; Vasan, Ramachandran S; Benjamin, Emelia J; Larson, Martin G; Zapol, Warren M; Cheng, Susan; Roh, Jason D; O'Donnell, Christopher J; Nguyen, Christopher; Levy, Daniel; Ho, Jennifer E.

Arterioscler Thromb Vasc Biol ; 42(2): e61-e73, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34809448

4.

UBA6 and NDFIP1 regulate the degradation of ferroportin.

Traeger, Lisa; Wiegand, Steffen B; Sauer, Andrew J; Corman, Benjamin H P; Peneyra, Kathryn M; Wunderer, Florian; Fischbach, Anna; Bagchi, Aranya; Malhotra, Rajeev; Zapol, Warren M; Bloch, Donald B.

Haematologica ; 107(2): 478-488, 2022 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-34320783

5.

Electronic cigarette vaping with aged coils causes acute lung injury in mice.

Goto, Shunsaku; Grange, Robert M H; Pinciroli, Riccardo; Rosales, Ivy A; Li, Rebecca; Boerboom, Sophie L; Ostrom, Katrina F; Marutani, Eizo; Wanderley, Hatus V; Bagchi, Aranya; Colvin, Robert B; Berra, Lorenzo; Minaeva, Olga; Goldstein, Lee E; Malhotra, Rajeev; Zapol, Warren M; Ichinose, Fumito; Yu, Binglan.

Arch Toxicol ; 96(12): 3363-3371, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36195745

6.

Hyperbaric phototherapy augments blood carbon monoxide removal.

Fischbach, Anna; Traeger, Lisa; Farinelli, William A; Ezaka, Mariko; Wanderley, Hatus V; Wiegand, Steffen B; Franco, Walfre; Bagchi, Arayna; Bloch, Donald B; Anderson, R Rox; Zapol, Warren M.

Lasers Surg Med ; 54(3): 426-432, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-34658052

7.

Veno-venous extracorporeal blood phototherapy increases the rate of carbon monoxide (CO) elimination in CO-poisoned pigs.

Fischbach, Anna; Wiegand, Steffen B; Zazzeron, Luca; Traeger, Lisa; di Fenza, Raffaele; Bagchi, Aranya; Farinelli, William A; Franco, Walfre; Korupolu, Sandeep; Arens, Jutta; Grassi, Luigi; Zadek, Francesco; Bloch, Donald B; Rox Anderson, R; Zapol, Warren M.

Lasers Surg Med ; 54(2): 256-267, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34350599

8.

Safety and practicality of high dose inhaled nitric oxide in emergency department COVID-19 patients.

Strickland, Brian; Albala, Lorenzo; Coffey, El Centro; Carroll, Ryan W; Zapol, Warren M; Ichinose, Fumito; Berra, Lorenzo; Harris, N Stuart.

Am J Emerg Med ; 58: 5-8, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35623183

9.

Hypoxia ameliorates brain hyperoxia and NAD⁺ deficiency in a murine model of Leigh syndrome.

Grange, Robert M H; Sharma, Rohit; Shah, Hardik; Reinstadler, Bryn; Goldberger, Olga; Cooper, Marissa K; Nakagawa, Akito; Miyazaki, Yusuke; Hindle, Allyson G; Batten, Annabelle J; Wojtkiewicz, Gregory R; Schleifer, Grigorij; Bagchi, Aranya; Marutani, Eizo; Malhotra, Rajeev; Bloch, Donald B; Ichinose, Fumito; Mootha, Vamsi K; Zapol, Warren M.

Mol Genet Metab ; 133(1): 83-93, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33752971

10.

Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumonia.

Safaee Fakhr, Bijan; Di Fenza, Raffaele; Gianni, Stefano; Wiegand, Steffen B; Miyazaki, Yusuke; Araujo Morais, Caio C; Gibson, Lauren E; Chang, Marvin G; Mueller, Ariel L; Rodriguez-Lopez, Josanna M; Ackman, Jeanne B; Arora, Pankaj; Scott, Louie K; Bloch, Donald B; Zapol, Warren M; Carroll, Ryan W; Ichinose, Fumito; Berra, Lorenzo.

Nitric Oxide ; 116: 7-13, 2021 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-34400339

11.

Intratracheal injection of nitric oxide, generated from air by pulsed electrical discharge, for the treatment of pulmonary hypertension in awake ambulatory lambs.

Yu, Binglan; Zadek, Francesco; Fischbach, Anna; Wiegand, Steffen B; Berra, Lorenzo; Bloch, Donald B; Zapol, Warren M.

Nitric Oxide ; 97: 11-15, 2020 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-31982629

12.

Ideation and assessment of a nitric oxide delivery system for spontaneously breathing subjects.

Gianni, Stefano; Morais, Caio C A; Larson, Grant; Pinciroli, Riccardo; Carroll, Ryan; Yu, Binglan; Zapol, Warren M; Berra, Lorenzo.

Nitric Oxide ; 104-105: 29-35, 2020 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-32835810

13.

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome.

Ferrari, Michele; Jain, Isha H; Goldberger, Olga; Rezoagli, Emanuele; Thoonen, Robrecht; Cheng, Kai-Hung; Sosnovik, David E; Scherrer-Crosbie, Marielle; Mootha, Vamsi K; Zapol, Warren M.

Proc Natl Acad Sci U S A ; 114(21): E4241-E4250, 2017 05 23.

Artigo em Inglês | MEDLINE | ID: mdl-28483998

14.

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome.

Schleifer, Grigorij; Marutani, Eizo; Ferrari, Michele; Sharma, Rohit; Skinner, Owen; Goldberger, Olga; Grange, Robert Matthew Henry; Peneyra, Kathryn; Malhotra, Rajeev; Wepler, Martin; Ichinose, Fumito; Bloch, Donald B; Mootha, Vamsi K; Zapol, Warren M.

Am J Physiol Lung Cell Mol Physiol ; 316(2): L391-L399, 2019 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-30520688

15.

Low guanylyl cyclase activity in Weddell seals: implications for peripheral vasoconstriction and perfusion of the brain during diving.

Hindle, Allyson G; Allen, Kaitlin N; Batten, Annabelle J; Hückstädt, Luis A; Turner-Maier, Jason; Schulberg, S Anne; Johnson, Jeremy; Karlsson, Elinor; Lindblad-Toh, Kerstin; Costa, Daniel P; Bloch, Donald B; Zapol, Warren M; Buys, Emmanuel S.

Am J Physiol Regul Integr Comp Physiol ; 316(6): R704-R715, 2019 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-30892912

16.

Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation.

Wang, Aizhou; Singh, Serena; Yu, Binglan; Bloch, Donald B; Zapol, Warren M; Kluger, Ronald.

Transfusion ; 59(1): 359-370, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30444016

17.

Nitric Oxide Story.

Zapol, Warren M.

Anesthesiology ; 130(3): 435-440, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30664059

18.

Nitric Oxide Decreases Acute Kidney Injury and Stage 3 Chronic Kidney Disease after Cardiac Surgery.

Lei, Chong; Berra, Lorenzo; Rezoagli, Emanuele; Yu, Binglan; Dong, Hailong; Yu, Shiqiang; Hou, Lihong; Chen, Min; Chen, Wensheng; Wang, Hongbing; Zheng, Qijun; Shen, Jie; Jin, Zhenxiao; Chen, Tao; Zhao, Rong; Christie, Emily; Sabbisetti, Venkata S; Nordio, Francesco; Bonventre, Joseph V; Xiong, Lize; Zapol, Warren M.

Am J Respir Crit Care Med ; 198(10): 1279-1287, 2018 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-29932345

19.

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells.

Nakagawa, Akito; Ferrari, Michele; Schleifer, Grigorij; Cooper, Marissa K; Liu, Chen; Yu, Binglan; Berra, Lorenzo; Klings, Elizabeth S; Safo, Ronni S; Chen, Qiukan; Musayev, Faik N; Safo, Martin K; Abdulmalik, Osheiza; Bloch, Donald B; Zapol, Warren M.

Mol Pharm ; 15(5): 1954-1963, 2018 05 07.

Artigo em Inglês | MEDLINE | ID: mdl-29634905

20.

Development of a portable mini-generator to safely produce nitric oxide for the treatment of infants with pulmonary hypertension.

Yu, Binglan; Ferrari, Michele; Schleifer, Grigorij; Blaesi, Aron H; Wepler, Martin; Zapol, Warren M; Bloch, Donald B.

Nitric Oxide ; 75: 70-76, 2018 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-29486304

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