Detalhe da pesquisa
1.
The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.
Int J Mol Sci
; 25(8)2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673962
2.
Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.
Int J Mol Sci
; 25(8)2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673995
3.
A framework for the integration of development and evolution: The forgotten legacy of James Meadows Rendel.
Stud Hist Philos Sci
; 105: 41-49, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38733743
4.
Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis.
Bioorg Chem
; 137: 106587, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37163812
5.
Monoclonal Antibodies: The Greatest Resource to Treat Multiple Myeloma.
Int J Mol Sci
; 24(4)2023 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834545
6.
Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome.
Int J Mol Sci
; 24(13)2023 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37445688
7.
Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives.
Int J Mol Sci
; 24(13)2023 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37445907
8.
Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.
Int J Mol Sci
; 24(10)2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37239824
9.
Development of isoquinolinone derivatives as immunoproteasome inhibitors.
Bioorg Med Chem Lett
; 55: 128478, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34838650
10.
Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells.
Chem Biodivers
; 19(2): e202100451, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871465
11.
Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.
Int J Mol Sci
; 23(22)2022 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430948
12.
Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.
Molecules
; 27(12)2022 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35744891
13.
Lead Discovery of SARS-CoV-2 Main Protease Inhibitors through Covalent Docking-Based Virtual Screening.
J Chem Inf Model
; 61(4): 2062-2073, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784094
14.
Immunoproteasome and Non-Covalent Inhibition: Exploration by Advanced Molecular Dynamics and Docking Methods.
Molecules
; 26(13)2021 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34279386
15.
Cleaning and Disinfectant Chemical Exposures and Temporal Associations with COVID-19 - National Poison Data System, United States, January 1, 2020-March 31, 2020.
MMWR Morb Mortal Wkly Rep
; 69(16): 496-498, 2020 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32324720
16.
Stage- and thermal-specific genetic architecture for preadult viability in natural populations of Drosophila melanogaster.
J Evol Biol
; 32(7): 683-693, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30924196
17.
Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells.
J Enzyme Inhib Med Chem
; 34(1): 1307-1313, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31307247
18.
Identification of 2-thioxoimidazolidin-4-one derivatives as novel noncovalent proteasome and immunoproteasome inhibitors.
Bioorg Med Chem Lett
; 28(3): 278-283, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29292224
19.
Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists.
Bioorg Med Chem
; 25(14): 3631-3637, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28571973
20.
Unintentional methadone and buprenorphine exposures in children: Developing prevention messages.
J Am Pharm Assoc (2003)
; 57(2S): S83-S86, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28292505