Detalhe da pesquisa
1.
Directed Evolution of Protein Catalysts.
Annu Rev Biochem
; 87: 131-157, 2018 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29494241
2.
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.
Proc Natl Acad Sci U S A
; 117(48): 30362-30369, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203677
3.
Minor Actinides Can Replace Essential Lanthanides in Bacterial Life.
Angew Chem Int Ed Engl
; 62(31): e202303669, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37074219
4.
RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.
Mol Cell
; 54(6): 975-986, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24813946
5.
Emergence of a Negative Activation Heat Capacity during Evolution of a Designed Enzyme.
J Am Chem Soc
; 141(30): 11745-11748, 2019 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282667
6.
Optimization of Enzyme Mechanism along the Evolutionary Trajectory of a Computationally Designed (Retro-)Aldolase.
J Am Chem Soc
; 139(36): 12541-12549, 2017 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28783336
7.
Characterizing Active Site Conformational Heterogeneity along the Trajectory of an Enzymatic Phosphoryl Transfer Reaction.
Angew Chem Int Ed Engl
; 55(38): 11533-7, 2016 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27534930
8.
trans-Acting arginine residues in the AAA+ chaperone ClpB allosterically regulate the activity through inter- and intradomain communication.
J Biol Chem
; 289(47): 32965-76, 2014 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253689
9.
The molecular mechanism of Hsp100 chaperone inhibition by the prion curing agent guanidinium chloride.
J Biol Chem
; 288(10): 7065-76, 2013 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23341453
10.
Elements in nucleotide sensing and hydrolysis of the AAA+ disaggregation machine ClpB: a structure-based mechanistic dissection of a molecular motor.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 582-95, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531492
11.
A sterile alpha-motif domain in NafY targets apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain.
J Biol Chem
; 286(8): 6321-8, 2011 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21156797
12.
Coupling of oligomerization and nucleotide binding in the AAA+ chaperone ClpB.
Biochemistry
; 50(5): 899-909, 2011 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21182296
13.
Design and engineering of artificial metalloproteins: from de novo metal coordination to catalysis.
Protein Eng Des Sel
; 342021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33635315
14.
Americium preferred: lanmodulin, a natural lanthanide-binding protein favors an actinide over lanthanides.
Chem Sci
; 12(47): 15581-15587, 2021 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35003587
15.
Analysis of electrostatic coupling throughout the laboratory evolution of a designed retroaldolase.
Protein Sci
; 30(8): 1617-1627, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938058
16.
Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins.
Nat Chem
; 12(11): 1008-1015, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929246
17.
Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate.
Nat Struct Mol Biol
; 25(1): 90-100, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29323281
18.
Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting.
Protein Eng Des Sel
; 29(9): 355-66, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27542390
19.
Efficient laboratory evolution of computationally designed enzymes with low starting activities using fluorescence-activated droplet sorting.
Protein Eng Des Sel
; 30(7): 531, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28873983