Pesquisa | BVS Integralidade em Saúde

1.

Atlas of fetal metabolism during mid-to-late gestation and diabetic pregnancy.

Perez-Ramirez, Cesar A; Nakano, Haruko; Law, Richard C; Matulionis, Nedas; Thompson, Jennifer; Pfeiffer, Andrew; Park, Junyoung O; Nakano, Atsushi; Christofk, Heather R.

Cell ; 187(1): 204-215.e14, 2024 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-38070508

2.

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.

Ben-Othman, Nouha; Vieira, Andhira; Courtney, Monica; Record, Fabien; Gjernes, Elisabet; Avolio, Fabio; Hadzic, Biljana; Druelle, Noémie; Napolitano, Tiziana; Navarro-Sanz, Sergi; Silvano, Serena; Al-Hasani, Keith; Pfeifer, Anja; Lacas-Gervais, Sandra; Leuckx, Gunter; Marroquí, Laura; Thévenet, Julien; Madsen, Ole Dragsbaek; Eizirik, Decio Laks; Heimberg, Harry; Kerr-Conte, Julie; Pattou, François; Mansouri, Ahmed; Collombat, Patrick.

Cell ; 168(1-2): 73-85.e11, 2017 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-27916274

3.

mTOR Signaling in Growth, Metabolism, and Disease.

Saxton, Robert A; Sabatini, David M.

Cell ; 168(6): 960-976, 2017 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-28283069

4.

Artemisinins Target GABA_A Receptor Signaling and Impair α Cell Identity.

Li, Jin; Casteels, Tamara; Frogne, Thomas; Ingvorsen, Camilla; Honoré, Christian; Courtney, Monica; Huber, Kilian V M; Schmitner, Nicole; Kimmel, Robin A; Romanov, Roman A; Sturtzel, Caterina; Lardeau, Charles-Hugues; Klughammer, Johanna; Farlik, Matthias; Sdelci, Sara; Vieira, Andhira; Avolio, Fabio; Briand, François; Baburin, Igor; Májek, Peter; Pauler, Florian M; Penz, Thomas; Stukalov, Alexey; Gridling, Manuela; Parapatics, Katja; Barbieux, Charlotte; Berishvili, Ekaterine; Spittler, Andreas; Colinge, Jacques; Bennett, Keiryn L; Hering, Steffen; Sulpice, Thierry; Bock, Christoph; Distel, Martin; Harkany, Tibor; Meyer, Dirk; Superti-Furga, Giulio; Collombat, Patrick; Hecksher-Sørensen, Jacob; Kubicek, Stefan.

Cell ; 168(1-2): 86-100.e15, 2017 Jan 12.

Artigo em Inglês | MEDLINE | ID: mdl-27916275

5.

Homeostasis, inflammation, and disease susceptibility.

Kotas, Maya E; Medzhitov, Ruslan.

Cell ; 160(5): 816-827, 2015 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-25723161

6.

ß-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.

Suriben, Rowena; Kaihara, Kelly A; Paolino, Magdalena; Reichelt, Mike; Kummerfeld, Sarah K; Modrusan, Zora; Dugger, Debra L; Newton, Kim; Sagolla, Meredith; Webster, Joshua D; Liu, Jinfeng; Hebrok, Matthias; Dixit, Vishva M.

Cell ; 163(6): 1457-67, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26627735

7.

The selection landscape and genetic legacy of ancient Eurasians.

Irving-Pease, Evan K; Refoyo-Martínez, Alba; Barrie, William; Ingason, Andrés; Pearson, Alice; Fischer, Anders; Sjögren, Karl-Göran; Halgren, Alma S; Macleod, Ruairidh; Demeter, Fabrice; Henriksen, Rasmus A; Vimala, Tharsika; McColl, Hugh; Vaughn, Andrew H; Speidel, Leo; Stern, Aaron J; Scorrano, Gabriele; Ramsøe, Abigail; Schork, Andrew J; Rosengren, Anders; Zhao, Lei; Kristiansen, Kristian; Iversen, Astrid K N; Fugger, Lars; Sudmant, Peter H; Lawson, Daniel J; Durbin, Richard; Korneliussen, Thorfinn; Werge, Thomas; Allentoft, Morten E; Sikora, Martin; Nielsen, Rasmus; Racimo, Fernando; Willerslev, Eske.

Nature ; 625(7994): 312-320, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38200293

8.

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses.

Zhou, Runhong; To, Kelvin Kai-Wang; Wong, Yik-Chun; Liu, Li; Zhou, Biao; Li, Xin; Huang, Haode; Mo, Yufei; Luk, Tsz-Yat; Lau, Thomas Tsz-Kan; Yeung, Pauline; Chan, Wai-Ming; Wu, Alan Ka-Lun; Lung, Kwok-Cheung; Tsang, Owen Tak-Yin; Leung, Wai-Shing; Hung, Ivan Fan-Ngai; Yuen, Kwok-Yung; Chen, Zhiwei.

Immunity ; 53(4): 864-877.e5, 2020 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-32791036

9.

Whole-body imaging with single-cell resolution by tissue decolorization.

Tainaka, Kazuki; Kubota, Shimpei I; Suyama, Takeru Q; Susaki, Etsuo A; Perrin, Dimitri; Ukai-Tadenuma, Maki; Ukai, Hideki; Ueda, Hiroki R.

Cell ; 159(4): 911-24, 2014 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-25417165

10.

Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.

Nobs, Samuel Philip; Kolodziejczyk, Aleksandra A; Adler, Lital; Horesh, Nir; Botscharnikow, Christine; Herzog, Ella; Mohapatra, Gayatree; Hejndorf, Sophia; Hodgetts, Ryan-James; Spivak, Igor; Schorr, Lena; Fluhr, Leviel; Kviatcovsky, Denise; Zacharia, Anish; Njuki, Suzanne; Barasch, Dinorah; Stettner, Noa; Dori-Bachash, Mally; Harmelin, Alon; Brandis, Alexander; Mehlman, Tevie; Erez, Ayelet; He, Yiming; Ferrini, Sara; Puschhof, Jens; Shapiro, Hagit; Kopf, Manfred; Moussaieff, Arieh; Abdeen, Suhaib K; Elinav, Eran.

Nature ; 624(7992): 645-652, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-38093014

11.

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53.

Jiang, Peng; Ren, Lejiao; Zhi, Li; Yu, Zhong; Lv, Fengxiang; Xu, Fengli; Peng, Wei; Bai, Xiaoyu; Cheng, Kunlun; Quan, Li; Zhang, Xiuqin; Wang, Xianhua; Zhang, Yan; Yang, Dan; Hu, Xinli; Xiao, Rui-Ping.

Mol Cell ; 81(3): 629-637.e5, 2021 02 04.

Artigo em Inglês | MEDLINE | ID: mdl-33400924

12.

Microbial gatekeepers: unraveling the role of the gut microbiota enzyme DPP4 in diabetes management.

Liao, Lijuan; Lin, Fan; Gao, Jiangtao.

Trends Biochem Sci ; 49(2): 99-100, 2024 02.

Artigo em Inglês | MEDLINE | ID: mdl-37770288

13.

Conditioning of naive CD4(+) T cells for enhanced peripheral Foxp3 induction by nonspecific bystander inflammation.

Thompson, Lucas J; Lai, Jen-Feng; Valladao, Andrea C; Thelen, Tennille D; Urry, Zoe L; Ziegler, Steven F.

Nat Immunol ; 17(3): 297-303, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26752376

14.

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.

Maschalidi, Sophia; Mehrotra, Parul; Keçeli, Burcu N; De Cleene, Hannah K L; Lecomte, Kim; Van der Cruyssen, Renée; Janssen, Pauline; Pinney, Jonathan; van Loo, Geert; Elewaut, Dirk; Massie, Ann; Hoste, Esther; Ravichandran, Kodi S.

Nature ; 606(7915): 776-784, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35614212

15.

Low-dose metformin targets the lysosomal AMPK pathway through PEN2.

Ma, Teng; Tian, Xiao; Zhang, Baoding; Li, Mengqi; Wang, Yu; Yang, Chunyan; Wu, Jianfeng; Wei, Xiaoyan; Qu, Qi; Yu, Yaxin; Long, Shating; Feng, Jin-Wei; Li, Chun; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Chen, Junjie; Yu, Yong; Huang, Xi; He, Ying; Yao, Luming; Zhang, Lei; Zhu, Mingxia; Wang, Wen; Wang, Zhi-Chao; Zhang, Mingliang; Bao, Yuqian; Jia, Weiping; Lin, Shu-Yong; Ye, Zhiyun; Piao, Hai-Long; Deng, Xianming; Zhang, Chen-Song; Lin, Sheng-Cai.

Nature ; 603(7899): 159-165, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35197629

16.

Regulation of glucose transporter translocation in health and diabetes.

Bogan, Jonathan S.

Annu Rev Biochem ; 81: 507-32, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-22482906

17.

A window in time for ß-cell regeneration.

Weidemann, Benjamin J; Bass, Joseph.

Genes Dev ; 34(23-24): 1559-1561, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33262142

18.

SUMO: From Bench to Bedside.

Chang, Hui-Ming; Yeh, Edward T H.

Physiol Rev ; 100(4): 1599-1619, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32666886

19.

Innervation of the pancreas in development and disease.

Agerskov, Rikke Hoegsberg; Nyeng, Pia.

Development ; 151(2)2024 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-38265192

20.

Virus-Induced Interferon-Î³ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.

Sestan, Marko; Marinovic, Sonja; Kavazovic, Inga; Cekinovic, Durdica; Wueest, Stephan; Turk Wensveen, Tamara; Brizic, Ilija; Jonjic, Stipan; Konrad, Daniel; Wensveen, Felix M; Polic, Bojan.

Immunity ; 49(1): 164-177.e6, 2018 07 17.

Artigo em Inglês | MEDLINE | ID: mdl-29958802

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